関: keratoderma、keratosis

WordNet

a skin condition marked by an overgrowth of layers of horny skin
any skin disorder consisting of a growth that appears horny (同)keratodermia

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/06/16 19:58:37」(JST)

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Keratosis (from keratinocyte, the prominent cell type in the epidermis, and -osis, abnormal) is a growth of keratin on the skin or on mucous membranes. More specifically, it can refer to:

actinic keratosis (also known as solar keratosis)
hydrocarbon keratosis
keratosis pilaris (KP, also known as follicular keratosis)
seborrheic keratosis

Actinic keratoses are pre-malignant growths. Seborrheic keratoses are not pre-malignant.

References

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1. 皮膚の良性病変の概要 overview of benign lesions of the skin
2. カウデン症候群などのPTEN過誤腫症候群 pten hamartoma tumor syndrome including cowden syndrome
3. 皮膚扁平上皮癌（SCC）の臨床的特徴および診断 clinical features and diagnosis of cutaneous squamous cell carcinoma scc
4. 実質臓器移植受容者における皮膚癌のマネージメント management of skin cancer in solid organ transplant recipients
5. 皮膚病変のダーモスコピー評価 dermoscopic evaluation of skin lesions

English Journal

Cutaneous Complications of Targeted Melanoma Therapy.

de Golian E1, Kwong BY1, Swetter SM1,2, Pugliese SB3.
Current treatment options in oncology.Curr Treat Options Oncol.2016 Nov;17(11):57. doi: 10.1007/s11864-016-0434-0.
OPINION STATEMENT: The landscape of advanced and metastatic melanoma therapy has shifted dramatically in recent years. Since 2011, eight drugs (ipilimumab, vemurafenib, dabrafenib, trametinib, cometinib, pembrolizumab, nivolumab, and talimogene laherparepvec) have received FDA approval for the treat
PMID 27645330

Proteomic profiling reveals candidate markers for arsenic-induced skin keratosis.

Guo Z1, Hu Q1, Tian J1, Yan L1, Jing C1, Xie HQ1, Bao W2, Rice RH3, Zhao B4, Jiang G1.
Environmental pollution (Barking, Essex : 1987).Environ Pollut.2016 Nov;218:34-38. doi: 10.1016/j.envpol.2016.08.035. Epub 2016 Aug 20.
Proteomics technology is an attractive biomarker candidate discovery tool that can be applied to study large sets of biological molecules. To identify novel biomarkers and molecular targets in arsenic-induced skin lesions, we have determined the protein profile of arsenic-affected human epidermal st
PMID 27552035

Histopathology and reflectance confocal microscopy features of photodamaged skin and actinic keratosis.

Tan JM1, Lambie D1,2, Sinnya S1, Sahebian A1, Soyer HP1, Prow TW3, Ardigò M4.
Journal of the European Academy of Dermatology and Venereology : JEADV.J Eur Acad Dermatol Venereol.2016 Nov;30(11):1901-1911. doi: 10.1111/jdv.13699. Epub 2016 Jun 14.
BACKGROUND: Actinic keratosis (AK) usually co-exists in areas of severe photodamage, but the clinical applicability of reflectance confocal microscopy (RCM) in diagnosing AK currently depends on a set of parameters yet to be defined in comparison to photodamaged skin (PD).OBJECTIVE: To correlate the
PMID 27298142

Japanese Journal

Efficacy and safety of a topical carbon suspension photoenhancer adjunctive to intense pulsed light treatment for pigmented lesions in Japanese patients: A pilot study