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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/07 18:50:42」(JST)

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1. 小児における慢性下痢の原因の概要 overview of the causes of chronic diarrhea in children
2. 小児における腎結石症の疫学および危険因子 epidemiology of and risk factors for nephrolithiasis in children
3. 栄養の吸収および吸収不良の機序 mechanisms of nutrient absorption and malabsorption
4. 吸収不良の臨床的特徴および診断 clinical features and diagnosis of malabsorption

A double-blind, randomized, placebo-controlled trial studying the effects of Saccharomyces boulardii on the gastrointestinal tolerability, safety, and pharmacokinetics of miglustat.

Remenova T1, Morand O2, Amato D3, Chadha-Boreham H4, Tsurutani S5, Marquardt T6.
Orphanet journal of rare diseases.Orphanet J Rare Dis.2015 Jun 19;10(1):81. [Epub ahead of print]
BACKGROUND: Gastrointestinal (GI) disturbances such as diarrhea and flatulence are the most frequent adverse effects associated with miglustat therapy in type 1 Gaucher disease (GD1) and Niemann-Pick disease type C (NP-C), and the most common recorded reason for stopping treatment during clinical tr
PMID 26084276

Fermentation in the small intestine contributes substantially to intestinal starch disappearance in calves.

Gilbert MS1, Pantophlet AJ2, Berends H3, Pluschke AM4, van den Borne JJ3, Hendriks WH3, Schols HA5, Gerrits WJ3.
The Journal of nutrition.J Nutr.2015 Jun;145(6):1147-55. doi: 10.3945/jn.114.208595. Epub 2015 Apr 15.
BACKGROUND: The proportion of starch disappearing from the small intestinal lumen is generally lower in ruminants than in monogastric animals, and there are indications that the starch digestion capacity in ruminants is limited.OBJECTIVES: Milk-fed calves were used to study the rate-limiting enzyme
PMID 25878206

Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal α-Glucosidases: Binding Conformation and Interaction for ntSI.

Kato A1, Zhang ZL2, Wang HY2, Jia YM2, Yu CY2, Kinami K1, Hirokami Y1, Tsuji Y1, Adachi I1, Nash RJ3, Fleet GW4,5, Koseki J6, Nakagome I6, Hirono S6.
The Journal of organic chemistry.J Org Chem.2015 May 1;80(9):4501-15. doi: 10.1021/acs.joc.5b00342. Epub 2015 Apr 13.
This paper identifies the required configuration and orientation of α-glucosidase inhibitors, miglitol, α-1-C-butyl-DNJ, and α-1-C-butyl-LAB for binding to ntSI (isomaltase). Molecular dynamics (MD) calculations suggested that the flexibility around the keyhole of ntSI is lower than that of ctSI
PMID 25843107

Steric hindrance by 2 amino acid residues determines the substrate specificity of isomaltase from Saccharomyces cerevisiae(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)

Yamamoto Keizo,Miyake Hideo,Kusunoki Masami [他],Osaki Shigeyoshi
Journal of bioscience and bioengineering 112(6), 545-550, 2011-12-00
… The structures of the E277A isomaltase mutant from Saccharomyces cerevisiae in complex with isomaltose or maltose were determined at resolutions of 1.80 and 1.40Å, respectively. … The root mean square deviations between the corresponding mainchain atoms of free isomaltase and the E277A-isomaltose complex structures and those of free isomaltase and the E277A-maltose complex structures were found to be 0.131Å and 0.083Å, respectively. …
NAID 110008897326

Jejunal Induction of SI and SGLT1 Genes in Rats by High-Starch/Low-Fat Diet Is Associated with Histone Acetylation and Binding of GCN5 on the Genes

Inoue Seiya,Mochizuki Kazuki,Goda Toshinao
Journal of nutritional science and vitaminology 57(2), 162-169, 2011-04-01
… The intestinal expression of genes involved in carbohydrate digestion and absorption, such as sucrase-isomaltase (SI) and sodium-dependent glucose cotransporter (SGLT1), is higher in rodents fed a high-starch/low-fat (HS) diet than in those fed a low-starch/high-fat (LS) diet. …
NAID 10030028908