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1. 鎌状赤血球症における血管閉塞症 vasoocclusion in sickle cell disease
2. 鎌状細胞貧血における臨床的ばらつき clinical variability in sickle cell anemia
3. 鎌状ヘモグロビン多量体：構造と機能特性 sickle hemoglobin polymer structure and functional properties
4. 膜透過性異常 xerocytosis
5. 鎌状赤血球症に対する特異的治療 specific therapies for sickle cell disease

Efficient refolding of a hydrophobic protein with multiple S-S bonds by on-resin immobilized metal affinity chromatography.

Sharapova OA, Yurkova MS, Laurinavichyute DK, Andronova SM, Fedorov AN, Severin SE, Severin ES.SourceMoscow Research Institute of Medical Ecology, Simpheropolski blvd.8, Moscow, 117638, Russia.
Journal of chromatography. A.J Chromatogr A.2011 Aug 5;1218(31):5115-9. Epub 2011 May 27.
The efficient refolding of recombinant proteins produced in the form of inclusion bodies (IBs) in Escherichia coli still is a complicated experimental problem especially for large hydrophobic highly disulfide-bonded proteins. The aim of this work was to develop highly efficient and simple refolding
PMID 21676401

Arginine vasopressin controls p27(Kip1) protein expression by PKC activation and irreversibly inhibits the proliferation of K-Ras-dependent mouse Y1 adrenocortical malignant cells.

Forti FL, Armelin HA.SourceDepartamento de Bioquimica, Instituto de Quimica, Universidade de Sao Paulo, Av. Prof. Lineu Prestes, 748-Bl 09 Inf., Sl 922, Cidade Universitaria, Cep 05508-900, Sao Paulo-SP, Brazil.
Biochimica et biophysica acta.Biochim Biophys Acta.2011 Aug;1813(8):1438-45. Epub 2011 May 5.
The neurohypophyseal hormone arginine vasopressin (AVP) is a classic mitogen in many cells. In K-Ras-dependent mouse Y1 adrenocortical malignant cells, AVP elicits antagonistic responses such as the activation of the PKC and the ERK1/2 mitogenic pathways to down-regulate cyclin D1 gene expression, w
PMID 21571010

Influence of Nonsteroidal Anti-inflammatory Drugs on the Antiplatelet Effects of Aspirin in Rats

Akagi Yuuki,Nio Yuta,Shimada Shuji,Aoyama Takao
Biological & Pharmaceutical Bulletin 34(2), 233-237, 2011
… Low-dose aspirin acts by irreversibly acetylating internal cyclooxygenase-1 (COX-1) on platelets, thereby suppressing platelet aggregation. …
NAID 130000402195

伊藤直哉
国際広報メディア・観光学ジャーナル = The Journal of International Media, Communication, and Tourism Studies 11, 19-34, 2010-11-15
… Such a qualitative change is expected to progress irreversibly in the future. …
NAID 120002646853