イオベルソール
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/15 21:14:12」(JST)
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Ioversol
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Systematic (IUPAC) name |
1-N,3-N-bis(2,3-dihydroxypropyl)-5-[2-hydroxy-N-(2-hydroxyethyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide
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Clinical data |
AHFS/Drugs.com |
Micromedex Detailed Consumer Information |
Identifiers |
ATC code |
V08AB07 (WHO) |
PubChem |
CID 3741 |
ChemSpider |
3610 N |
UNII |
N3RIB7X24K N |
KEGG |
D01555 Y |
ChEMBL |
CHEMBL1200614 N |
Chemical data |
Formula |
C18H24I3N3O9 |
Molar mass |
807.11127 |
SMILES
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C(CO)N(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)CO
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InChI
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InChI=1S/C18H24I3N3O9/c19-13-11(17(32)22-3-8(29)5-26)14(20)16(24(1-2-25)10(31)7-28)15(21)12(13)18(33)23-4-9(30)6-27/h8-9,25-30H,1-7H2,(H,22,32)(H,23,33) N
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Key:AMDBBAQNWSUWGN-UHFFFAOYSA-N N
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NY (what is this?) (verify) |
Ioversol (INN) is an organoiodine compound that used as a contrast medium. It features both a high iodine content, as well as several hydrophilic groups.
Contrast media (V08)
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X-ray and CT |
Iodinated,
Water soluble
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Nephrotropic,
high osmolar
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- Diatrizoic acid#
- Metrizoic acid
- Iodamide
- Iotalamic acid
- Ioxitalamic acid
- Ioglicic acid
- Acetrizoic acid
- Iocarmic acid
- Methiodal
- Diodone
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Nephrotropic,
low osmolar
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- Metrizamide
- Iohexol#
- Ioxaglic acid
- Iopamidol
- Iopromide
- Iotrolan
- Ioversol
- Iopentol
- Iodixanol
- Iomeprol
- Iobitridol
- Ioxilan
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Hepatotropic
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- Iodoxamic acid
- Iotroxic acid
- Ioglycamic acid
- Adipiodone
- Iobenzamic acid
- Iopanoic acid
- Iocetamic acid
- Sodium iopodate
- Tyropanoic acid
- Calcium iopodate
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Iodinated,
Water insoluble
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- Ethyl esters of iodised fatty acids
- Iopydol
- Propyliodone
- Iofendylate
- Lipiodol
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Non-iodinated
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MRI |
Paramagnetic
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- Gadolinium-based: Gadobenic acid
- Gadobutrol
- Gadodiamide
- Gadofosveset
- Gadolinium
- Gadopentetic acid
- Gadoteric acid
- Gadoteridol
- Gadoversetamide
- Gadoxetic acid
Other: Ferric ammonium citrate
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Superparamagnetic
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- Ferumoxsil
- Ferristene
- Iron oxide, nanoparticles
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Other
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Ultrasound |
- Microspheres of human albumin
- Microparticles of galactose
- Perflenapent
- Microspheres of phospholipids
- Sulfur hexafluoride
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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UpToDate Contents
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- 1. 造影剤に対する即時型過敏反応:臨床症状、診断、および治療 immediate hypersensitivity reactions to radiocontrast media clinical manifestations diagnosis and treatment
- 2. 造影剤に対する即時型過敏反応:再発反応の予防 immediate hypersensitivity reactions to radiocontrast media prevention of recurrent reactions
- 3. 造影剤誘発性腎症の予防 prevention of contrast induced nephropathy
English Journal
- An observational study to evaluate the efficiency and safety of ioversol pre-filled syringes compared with ioversol bottles in contrast-enhanced examinations.
- Vogl TJ, Wessling J, Buerke B.SourceDepartment of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Frankfurt.
- Acta radiologica (Stockholm, Sweden : 1987).Acta Radiol.2012 Oct 1;53(8):914-20. doi: 10.1258/ar.2012.120303. Epub 2012 Sep 14.
- Background The use of pre-filled syringes for contrast media (CM) administration allows efficient and optimized workflow during radiologic diagnostic procedures, and reduces the risk of contamination, providing benefits for both patients and healthcare workers. Purpose To compare the efficiency and
- PMID 22983259
- Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using (18)F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth.
- Flores LG 2nd, Yeh HH, Soghomonyan S, Young D, Bankson J, Hu Q, Alauddin M, Huff V, Gelovani JG.SourceDepartment of Experimental Diagnostic Imaging, UT MD Anderson Cancer Center, Houston, TX, USA.
- Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.Mol Imaging Biol.2012 Aug 9. [Epub ahead of print]
- PURPOSE: The understanding of the role of genetic alterations in Wilms tumor development could be greatly advanced using a genetically engineered mouse models that can replicate the development and progression of this disease in human patients and can be monitored using non-invasive structural and m
- PMID 22875335
Japanese Journal
- Single-Detector CTを用いた腹部骨盤CTにおける造影剤低容量化の試み : イオヘキソール300(オムニパーク300,100mlシリンジ製剤)とイオベルソール320(オプチレイ320,75mlシリンジ製剤)を用いて
- 朔 円香,村上 純滋,中村 雄介,山口 俊博,小森 哲士,木村 正彦,小栗 修一,野口 智幸,飯田 崇,神谷 武志
- Fukuoka Acta Medica 95(5), 118-123, 2004-05-25
- … Materials and Methods : One hundred ml of Iohexol 300 and 75 ml of Ioversol 320 were compared in a prospective CT study about their imaging quality. …
- NAID 120002834498
- 非イオン性低浸透圧造影剤ioxilanの心室細動誘発作用
- 三角 一浩,立野 大樹,藤木 誠 [他],三浦 直樹,坂本 紘
- The journal of veterinary medical science 62(4), 421-426, 2000-04-25
- … ioxilanの心室細動(VF)誘発作用について, 同じ非イオン性低浸透圧造影剤であるioversol, iomeprol, およびiopromideと比較検討した.また心室細動発現に対する造影剤中のNa^+濃度の影響について検討するために, ioversol, iomeprol, およびiopromideにNaClを添加し, Na^+濃度を9および20mmol / L Na^+としたももについても比較を行った.実験には7頭のビーグル犬を使用し, 麻酔下にて右冠状動脈内にカテーテルを楔入させ, …
- NAID 110003920335
- 頭部造影CTにおけるIoversol 320/75ml syringeの造影効果の検討
Related Links
- Ioversol is in a group of drugs called radiopaque (RAY dee oh payk) contrast agents. Ioversol contains iodine, a substance that absorbs x-rays. Radiopaque contrast agents are used to allow blood vessels, organs, and other non ...
- ioversol /io·ver·sol/ (-ver´sol) a nonionic contrast medium used in angiography and urography and for contrast enhancement in computed tomography. ioversol [i′over′sol] a nonionic contrast medium used in angiography and urography ...
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