イオプロミド
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/23 00:59:08」(JST)
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Iopromide
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Systematic (IUPAC) name |
1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-1-N-methylbenzene-1,3-dicarboxamide
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Clinical data |
AHFS/Drugs.com |
International Drug Names |
Identifiers |
CAS Number |
73334-07-3 |
ATC code |
V08AB05 (WHO) |
PubChem |
CID 3736 |
ChemSpider |
3605 N |
UNII |
712BAC33MZ N |
KEGG |
D01893 Y |
ChEBI |
CHEBI:63578 N |
ChEMBL |
CHEMBL1725 N |
Chemical data |
Formula |
C18H24I3N3O8 |
Molar mass |
791.11187 |
SMILES
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CN(CC(CO)O)C(=O)c1c(c(c(c(c1I)NC(=O)COC)I)C(=O)NCC(CO)O)I
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InChI
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InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29) N
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Key:DGAIEPBNLOQYER-UHFFFAOYSA-N N
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NY (what is this?) (verify) |
Iopromide is a molecule used as a contrast medium. It is marketed under the name Ultravist which is produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use.[1]
It is commonly used in radiographic studies such as intravenous urograms, brain computer tomography (CT) and CT pulmonary angiograms (CTPAs).
Notes
- ^ The entry on Bayer Healthcare's website about Ultravist
External links
- Bayer Schering Pharma global Ultravist Website
Contrast media (V08)
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X-ray and CT |
Iodinated,
Water soluble
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Nephrotropic,
high osmolar
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- Diatrizoic acid#
- Metrizoic acid
- Iodamide
- Iotalamic acid
- Ioxitalamic acid
- Ioglicic acid
- Acetrizoic acid
- Iocarmic acid
- Methiodal
- Diodone
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Nephrotropic,
low osmolar
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- Metrizamide
- Iohexol#
- Ioxaglic acid
- Iopamidol
- Iopromide
- Iotrolan
- Ioversol
- Iopentol
- Iodixanol
- Iomeprol
- Iobitridol
- Ioxilan
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Hepatotropic
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- Iodoxamic acid
- Iotroxic acid
- Ioglycamic acid
- Adipiodone
- Iobenzamic acid
- Iopanoic acid
- Iocetamic acid
- Sodium iopodate
- Tyropanoic acid
- Calcium iopodate
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Iodinated,
Water insoluble
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- Ethyl esters of iodised fatty acids
- Iopydol
- Propyliodone
- Iofendylate
- Lipiodol
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Non-iodinated
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MRI |
Paramagnetic
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- Gadolinium-based: Gadobenic acid
- Gadobutrol
- Gadodiamide
- Gadofosveset
- Gadolinium
- Gadopentetic acid
- Gadoteric acid
- Gadoteridol
- Gadoversetamide
- Gadoxetic acid
Other: Ferric ammonium citrate
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Superparamagnetic
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- Ferumoxsil
- Ferristene
- Iron oxide, nanoparticles
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Other
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Ultrasound |
- Microspheres of human albumin
- Microparticles of galactose
- Perflenapent
- Microspheres of phospholipids
- Sulfur hexafluoride
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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UpToDate Contents
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- 1. 造影剤に対する即時型過敏反応:臨床症状、診断、および治療 immediate hypersensitivity reactions to radiocontrast media clinical manifestations diagnosis and treatment
- 2. 造影剤に対する即時型過敏反応:再発反応の予防 immediate hypersensitivity reactions to radiocontrast media prevention of recurrent reactions
English Journal
- Advanced oxidation of iodinated X-ray contrast media in reverse osmosis brines: The influence of quenching.
- Azerrad SP1, Gur-Reznik S1, Heller-Grossman L1, Dosoretz CG2.
- Water research.Water Res.2014 Oct 1;62:107-16. doi: 10.1016/j.watres.2014.05.041. Epub 2014 Jun 6.
- Among the main restrictions for the implementation of advanced oxidation processes (AOPs) for removal of micropollutants present in reverse osmosis (RO) brines of secondary effluents account the quenching performed by background organic and inorganic constituents. Natural organic matter (NOM) and so
- PMID 24945978
- Co-metabolic oxidation of pharmaceutical compounds by a nitrifying bacterial enrichment.
- Dawas-Massalha A1, Gur-Reznik S1, Lerman S1, Sabbah I2, Dosoretz CG3.
- Bioresource technology.Bioresour Technol.2014 Sep;167:336-42. doi: 10.1016/j.biortech.2014.06.003. Epub 2014 Jun 17.
- The biotransformation of five selected pharmaceuticals ibuprofen (IBP), ketoprofen (KTP), carbamazepine (CBZ), dexamethasone (DXM) and iopromide (IOP) by a stable nitrifying enrichment culture was investigated at concentrations ranging between 25μg/L and 2mg/L. Complete biotransformation was observ
- PMID 24997377
- Biodegradation of the X-ray contrast agent iopromide and the fluoroquinolone antibiotic ofloxacin by the white rot fungus Trametes versicolor in hospital wastewaters and identification of degradation products.
- Gros M1, Cruz-Morato C2, Marco-Urrea E2, Longrée P3, Singer H3, Sarrà M2, Hollender J3, Vicent T2, Rodriguez-Mozaz S4, Barceló D5.
- Water research.Water Res.2014 Sep 1;60:228-41. doi: 10.1016/j.watres.2014.04.042. Epub 2014 May 8.
- This paper describes the degradation of the X-ray contrast agent iopromide (IOP) and the antibiotic ofloxacin (OFLOX) by the white-rot-fungus Trametes versicolor. Batch studies in synthetic medium revealed that between 60 and 80% of IOP and OFLOX were removed when spiked at approximately 12 mg L(-
- PMID 24867600
Japanese Journal
- 非イオン性造影剤(イオプロミド)投与後に心電図でST低下を来した1症例
- High iodine concentration contrast material for noninvasive multislice computed tomography coronary angiography : iopromide 370 versus iomeprol 400
- 各種水溶性造影剤のラット腎臓に及ぼす影響 : 近位尿細管上皮細胞の空胞化からみた形態学的検討
- 脈管学 : 日本脈管学会機関誌 : the journal of Japanese College of Angiology 42(2), 123-130, 2002-02-25
- NAID 10008040900
Related Links
- 薬品名 イオプロミド注「FRI」 承認年月日 2010年7月15日 承認番号他コード一覧 (PDF:61KB) 輸入先 バイエル・ファーマ社(ドイツ連邦共和国) 販売元 富士フイルムRIファーマ株式会社 インタビューフォーム (PDF:807KB) イオプロミド ...
- Iopromide Drug Information from Drugs.com. Includes Iopromide side effects, interactions and indications. ... Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the ...
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