WordNet

relating to areas between the layers of the skin; "an intradermal injection" (同)intradermic, intracutaneous
into the skin

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Propacetamol-Induced Injection Pain Is Associated with Activation of Transient Receptor Potential Vanilloid 1 Channels.

Schillers F1, Eberhardt E1, Leffler A1, Eberhardt M2.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2016 Oct;359(1):18-25. doi: 10.1124/jpet.116.233452. Epub 2016 Jul 25.
Propacetamol (PPCM) is a prodrug of paracetamol (PCM), which was generated to increase water solubility of PCM for intravenous delivery. PPCM is rapidly hydrolyzed by plasma esterases to PCM and diethylglycine and shares some structural and metabolic properties with lidocaine. Although PPCM is consi
PMID 27457427

Urinary metabolite profiling provides potential differentiation to explore the mechanisms of adjuvant-induced arthritis in rats.

Jiang H1,2, Liu J1, Wang T3, Gao JR1, Sun Y1, Huang CB1, Meng M1, Qin XJ3.
Biomedical chromatography : BMC.Biomed Chromatogr.2016 Sep;30(9):1397-405. doi: 10.1002/bmc.3697. Epub 2016 Mar 7.
To explore the pathogenesis of rheumatoid arthritis (RA) from the perspective of metabolomics, gas chromatography time-of-flight mass spectrometry (GC-TOF/MS) technology was used to observe changes in the metabolic profiles of urine output from rats with adjuvant-induced arthritis (AA). Sprague-Dawl
PMID 26856389

Needle-free nasal delivery of glucagon for treatment of diabetes-related severe hypoglycemia: toxicology of polypropylene resin used in delivery device.

Reno FE1, Edwards CN2, Bendix Jensen M2, Török-Bathó M3, Esdaile DJ3, Piché C4, Triest M4, Carballo D4.
Cutaneous and ocular toxicology.Cutan Ocul Toxicol.2016 Sep;35(3):242-7. doi: 10.3109/15569527.2015.1089884. Epub 2015 Oct 1.
CONTEXT: The intranasal route is a promising route of administration for several emergency rescue drugs including naloxone and glucagon. Glucagon nasal powder (GNP) is a novel, needle-free delivery system for intranasal administration of glucagon for the treatment of severe hypoglycemia, an infreque
PMID 26426957

The Use of an Artificial Skin Model to Study Transdermal Absorption of Drugs in Inflamed Skin

Oshima Shinji,Suzuki Chihiro,Yajima Rina [他],Egawa Yuya,Hosoya Osamu,Juni Kazuhiko,Seki Toshinobu
Biological and Pharmaceutical Bulletin 35(2), 203-209, 2012
… In the in vivo experiments, FP absorption was suppressed in rats with inflamed skin induced by an intracutaneous injection of a mixed solution of λ-carrageenan, zymosan, and casein. …
NAID 130001872294