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- 1. 細菌性髄膜炎の病因および病態生理 pathogenesis and pathophysiology of bacterial meningitis
- 2. アムホテリシンBの薬理 pharmacology of amphotericin b
English Journal
- The estrogen-dependent baroreflex dysfunction caused by nicotine in female rats is mediated via NOS/HO inhibition: Role of sGC/PI3K/MAPKERK.
- Fouda MA1, El-Gowelli HM1, El-Gowilly SM1, El-Mas MM2.
- Toxicology and applied pharmacology.Toxicol Appl Pharmacol.2015 Dec 15;289(3):466-73. doi: 10.1016/j.taap.2015.10.014. Epub 2015 Oct 24.
- We have previously reported that estrogen (E2) exacerbates the depressant effect of chronic nicotine on arterial baroreceptor activity in female rats. Here, we tested the hypothesis that this nicotine effect is modulated by nitric oxide synthase (NOS) and/or heme oxygenase (HO) and their downstream
- PMID 26597895
- Two TRPV1 receptor antagonists are effective in two different experimental models of migraine.
- Meents JE1, Hoffmann J, Chaplan SR, Neeb L, Schuh-Hofer S, Wickenden A, Reuter U.
- The journal of headache and pain.J Headache Pain.2015 Dec;16:57. doi: 10.1186/s10194-015-0539-z. Epub 2015 Jun 24.
- BACKGROUND: The capsaicin and heat responsive ion channel TRPV1 is expressed on trigeminal nociceptive neurons and has been implicated in the pathophysiology of migraine attacks. Here we investigate the efficacy of two TRPV1 channel antagonists in blocking trigeminal activation using two in vivo mod
- PMID 26109436
- Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons.
- Hatanaka Y1, Inoue K2, Oikawa M1, Kamimura S1, Ogonuki N1, Kodama EN3, Ohkawa Y4, Tsukada Y5, Ogura A6.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Nov 24;112(47):14641-6. doi: 10.1073/pnas.1512775112. Epub 2015 Nov 6.
- Substantial proportions of mammalian genomes comprise repetitive elements including endogenous retrotransposons. Although these play diverse roles during development, their appropriate silencing is critically important in maintaining genomic integrity in the host cells. The major mechanism for retro
- PMID 26546670
Japanese Journal
- Milnacipran Inhibits Oxaliplatin-Induced Mechanical Allodynia through Spinal Action in Mice
- Andoh Tsugunobu,Kitamura Ryo,Kuraishi Yasushi
- Biological and Pharmaceutical Bulletin 38(1), 151-154, 2015
- … Intrathecal injections of milnacipran (2.1–21 µg/site) also significantly and dose-dependently inhibited mechanical allodynia, but intracisternal and intracereboventricular injections at the same doses did not. …
- NAID 130004872225
- ラットくも膜下出血モデルにおける脳血管攣縮のメカニズム : コレステロールによる制御機構
- 吉野 弘子
- 山口医学 63(2), 123-131, 2014-05-01
- … Results:SAH-induced CV was markedly reversed by intracisternal infusion with Y27632(10μM),a ROK-inhibitor. …
- NAID 120005477827
- 遺伝子は動く
- 穂積 信道
- 了徳寺大学研究紀要 (8), 1-15, 2014
- NAID 40020041362
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- intracisternal [in″trah-sis-ter´nal] within a subarachnoid cistern. in·tra·cis·ter·nal (in'tră-sis-tĕr'năl), Within one of the subarachnoid cisternae; usually refers to the introduction of a cannula into the cerebellomedullary cistern for aspiration ...
- :situated within, occurring within, or administered by entering a cisterna <intracisternal granules> <an intracisternal injection> ... Seen and Heard What made you want to look up intracisternal? Please tell us where you read or heard ...
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