Determinants of bluetongue virus virulence in murine models of disease.
Caporale M, Wash R, Pini A, Savini G, Franchi P, Golder M, Patterson-Kane J, Mertens P, Di Gialleonardo L, Armillotta G, Lelli R, Kellam P, Palmarini M.SourceMedical Research Council-University of Glasgow Centre for Virus Research, Garscube Campus, 464 Bearsden Road, Glasgow G61 1QH, United Kingdom. massimo.palmarini@glasgow.ac.uk.
Journal of virology.J Virol.2011 Nov;85(21):11479-89. Epub 2011 Aug 24.
Bluetongue is a major infectious disease of ruminants that is caused by bluetongue virus (BTV). In this study, we analyzed virulence and genetic differences of (i) three BTV field strains from Italy maintained at either a low (L strains) or high (H strains) passage number in cell culture and (ii) th
From High-Throughput Cell Culture Screening to Mouse Model: Identification of New Inhibitor Classes against Prion Disease.
Geissen M, Leidel F, Eiden M, Hirschberger T, Fast C, Bertsch U, Tavan P, Giese A, Kretzschmar H, Schatzl HM, Groschup MH.SourceFriedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Institute for Novel and Emerging Infectious Diseases, Suedufer 10, 17493 Greifswald-Insel Riems (Germany); Department of Vascular Medicine, Universitatsklinikum Hamburg-Eppendorf (UKE), Martinistrase 52, 20246 Hamburg (Germany).
ChemMedChem.ChemMedChem.2011 Oct 4;6(10):1928-37. doi: 10.1002/cmdc.201100119. Epub 2011 Jul 13.
Transmissible spongiform encephalopathies (TSE) or prion diseases belong to a category of fatal and so far untreatable neurodegenerative conditions. All prion diseases are characterized by both degeneration in the central nervous system (CNS) in humans and animals and the deposition and accumulation
Lesions of the Central Nervous System Induced by Intracerebral Inoculation of BALB/c Mice with Rabies Virus (CVS-11)
KOJIMA Daisuke,PARK Chun-Ho,TSUJIKAWA Shintarou,KOHARA Keiko,HATAI Hitoshi,OYAMADA Toshifumi,NOGUCHI Akira,INOUE Satoshi
Journal of Veterinary Medical Science advpub(0), 1003130197, 2010
… BALB/c mice were inoculated intracerebrally with fixed rabies virus (CVS-11) and pathomorphological changes in the central nervous system were studied. …
Journal of Veterinary Medical Science 71(10), 1331-1336, 2009
… Intracerebrally immunized mice were completely protected from death and the neurological signs of infection, whereas the IM or SC immunization only partly protected the mice. …
(redirected from intracerebrally). Also found in: Medical, 0.01 sec. in・tra・cer・e・bral ( n tr -s -r br l, -s r -). adj. Occurring or situated within the cerebrum: an intracerebral hemorrhage. in tra・cer・e bral・ly adv. ThesaurusLegend: Synonyms Related ...