a part of the cell containing DNA and RNA and responsible for growth and reproduction (同)cell_nucleus, karyon
(astronomy) the center of the head of a comet; consists of small solid particles of ice and frozen gas that vaporizes on approaching the sun to form the coma and tail
any histologically identifiable mass of neural cell bodies in the brain or spinal cord
The interposed nucleus is part of the deep cerebellar complex and is composed of the globose nucleus and the emboliform nucleus. It is located in the roof (dorsal aspect) of the fourth ventricle, lateral to the fastigial nucleus. It receives its afferent supply from the anterior lobe of the cerebellum and sends output via the superior cerebellar peduncle to the red nucleus.
The interposed nucleus is located in the paravermis of the cerebellum. It receives input from the ipsilateral posterior external arcuate fibers (cuneocerebellar tract) and the dorsal spinocerebellar tract, which originate in the accessory cuneate nucleus and the posterior thoracic nucleus, respectively. The interposed nucleus is responsible for coordinating agonist/antagonist muscle pairs, and therefore a lesion in this area causes tremor.
The interposed nucleus is smaller than the dentate but larger than the fastigial nucleus.
Function
Functionally, it modulates muscle stretch reflexes of proximal limb muscles. The cerebellar interpositus nucleus is also required in delayed Pavlovian conditioning.[1]
References
^Clark, Robert E.; Zhang, Andrew A.; Lavond, David G. (1992). "Reversible lesions of the cerebellar interpositus nucleus during acquisition and retention of a classically conditioned behavior". Behavioral Neuroscience. 106 (6): 879–888. doi:10.1037/0735-7044.106.6.879.
Neuroscience.Neuroscience.2016 Jan 4;317:12-22. doi: 10.1016/j.neuroscience.2015.12.055. [Epub ahead of print]
In spite of the existence of pedunculopontine tegmental nucleus (PPTg) projections to cerebellar nuclei, their nature and functional role is unknown. These fibers may play a crucial role in postural control and may be involved in the beneficial effects induced by deep-brain stimulation (DBS) of brai
Maternal iron deficiency worsens the associative learning deficits and hippocampal and cerebellar losses in a rat model of fetal alcohol spectrum disorders.
Huebner SM1, Tran TD2, Rufer ES1, Crump PM3, Smith SM1.
BACKGROUND: Gestational alcohol exposure causes lifelong physical and neurocognitive deficits collectively referred to as fetal alcohol spectrum disorders (FASDs). Micronutrient deficiencies are common in pregnancies of alcohol-abusing women. Here we show the most common micronutrient deficiency of
Cerebellar interpositus nuclear and gastric vagal afferent inputs reach and converge onto glycemia-sensitive neurons of the ventromedial hypothalamic nucleus in rats
Neuroscience research : the official journal of the Japan Neuroscience Society 48(4), 405-417, 2004-04-01
Cerebellar interpositus nuclear and gastric vagal afferent inputs reach and converge onto glycemia-sensitive neurons of the ventromedial hypothalamic nucleus in rats
in·ter·po·si·tus nu·cle·us collective term denoting the globosus nucleus and emboliform nucleus of the cerebellum. Synonym(s): nucleus interpositus ... Disclaimer All content on this website, including dictionary, thesaurus, literature ...
Related to Nucleus interpositus: red nucleus, dentate nucleus of cerebellum, Fastigial nucleus cerebellum [ser″ĕ-bel´um] the part of the metencephalon situated on the back of the brainstem, to which it is attached by three brain. ...
