WordNet

any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system

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1. 乾癬の治療 treatment of psoriasis
2. 乾癬の病態生理 pathophysiology of psoriasis
3. 乾癬の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of psoriasis
4. クローン病の内科的マネージメントにおける試験研究治療 investigational therapies in the medical management of crohn disease
5. 乾癬性関節炎の治療 treatment of psoriatic arthritis

Identification of IL-23p19 as an endothelial proinflammatory peptide that promotes gp130-STAT3 signaling.

Espígol-Frigolé G1, Planas-Rigol E2, Ohnuki H3, Salvucci O3, Kwak H3, Ravichandran S4, Luke B4, Cid MC5, Tosato G6.
Science signaling.Sci Signal.2016 Mar 15;9(419):ra28. doi: 10.1126/scisignal.aad2357.
Interleukin-23 (IL-23), a heterodimeric cytokine composed of the unique p19 peptide (IL-23p19) and a peptide called IL-12p40, which is shared with IL-12, is implicated in Crohn's disease, rheumatoid arthritis, psoriasis, and other immune-mediated inflammatory diseases. Endothelial cells produce the
PMID 26980441

Cai Y1, Tan W2, Shen X1, Zhu Y1, Gao Y1, Sui A1, Lu Q1, Zhong Y3, Xie B4.
Experimental eye research.Exp Eye Res.2016 Mar 14;146:242-251. doi: 10.1016/j.exer.2016.02.008. [Epub ahead of print]
Interleukin-23 (IL-23) is a heterodimeric cytokine that consists of p19, a novel subunit, and p40, which is shared by IL-12. IL-23 has been demonstrated to play an important role in autoimmunity and tumor growth. However, the role of IL-23 in ocular neovascularization (NV) diseases remains unclear.
PMID 26980350

Interleukin 23 regulates the functions of human decidual immune cells during early pregnancy.

Cai JY1, Li MJ2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Jan 15;469(3):340-4. doi: 10.1016/j.bbrc.2015.11.118. Epub 2015 Nov 30.
BACKGROUND: This study investigated the effects of interleukin 23 (IL-23) on the production of cytokines (IL-1, IL-4, IL-10, and IL-17), the differentiation of Treg/Th17 and STAT3 (i.e., signal transducer and activator of transcription 3) in human decidual immune cells (DICs) during early pregnancy.
PMID 26657845