- 関
- IL-12 receptor
WordNet
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- any of several lymphokines that promote macrophages and killer T cells and B cells and other components of the immune system
PrepTutorEJDIC
- =sense organ / 受信装置
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/28 19:32:39」(JST)
[Wiki en表示]
| interleukin 12 receptor, beta 1 |
| Identifiers |
| Symbol |
IL12RB1 |
| Alt. symbols |
IL12RB, CD212 |
| Entrez |
3594 |
| HUGO |
5971 |
| OMIM |
601604 |
| RefSeq |
NM_005535 |
| UniProt |
P42701 |
| Other data |
| Locus |
Chr. 19 p13.1 |
| beta 2 subunit, interleukin 12 receptor, beta 2 |
| Identifiers |
| Symbol |
IL12RB2 |
| Entrez |
3595 |
| HUGO |
5972 |
| OMIM |
601642 |
| RefSeq |
NM_001559 |
| UniProt |
Q99665 |
| Other data |
| Locus |
Chr. 1 p31.3-31.2 |
Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12. It consists of beta 1[1] and beta 2 subunits.[2]
References
- ^ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. PMID 7911493.
- ^ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. doi:10.1073/pnas.93.24.14002. PMC 19484. PMID 8943050.
External links
- Receptors, Interleukin-12 at the US National Library of Medicine Medical Subject Headings (MeSH)
|
Cytokine receptors
|
|
Chemokine receptor
(GPCRs) |
| CC |
- CCR1 / CCRL1
- CCR2
- CCRL2
- CCR3
- CCR4
- CCR5
- CCR6
- CCR7
- CCR8
- CCR9
- CCR10
|
|
| CXC |
- IL-8
- CXCR3
- CXCR4
- CXCR5
- CXCR6
- CXCR7
|
|
| Other |
|
|
|
| TNF receptor |
| 1-10 |
- TNFR1 (TNFRSF1A)
- TNFR2 (TNFRSF1B)
- LTBR (TNFRSF3)
- CD134 (TNFRSF4)
- CD40 (TNFRSF5)
- Fas receptor (TNFRSF6)
- DcR3 (TNFRSF6B)
- CD27 (TNFRSF7)
- CD30 (TNFRSF8)
- CD137 (TNFRSF9)
|
|
| 11-20 |
- DR4 (TNFRSF10A)
- DR5 (TNFRSF10B)
- DcR1 (TNFRSF10C)
- DcR2 (TNFRSF10D)
- RANK (TNFRSF11A)
- Osteoprotegerin (TNFRSF11B)
- TweakR (TNFRSF12A)
- TACI (TNFRSF13B)
- BAFFR (TNFRSF13C)
- HVEM (TNFRSF14)
- NGFR (TNFRSF16)
- BCMA (TNFRSF17)
- GITR (TNFRSF18)
- TAJ/TROY (TNFRSF19)
|
|
| 21-27 |
- DR6 (TNFRSF21)
- DR3 (TNFRSF25)
- EDA2R (TNFRSF27)
|
|
|
| JAK-STAT |
| Type I |
| γ-chain |
- Interleukin receptors
- IL2R / IL2RA/IL2RB / IL15R
- IL4R / IL13R / IL13RA1 / IL13RA2
- IL7R / IL7RA
- IL9R
- IL21R
|
|
| β-chain |
- Interleukin receptors
- IL3R / IL3RA
- IL5R / IL5RA
- GM-CSF
|
|
| gp130 |
- Interleukin receptors
- IL6RA
- 11/IL11RA
- 27/IL27RA
- OSMR
- LIFR
- CNTFR
|
|
| IL12RB1 |
- Interleukin receptors
- IL12R/IL12RB1/IL12RB2
- IL23R23
|
|
| Other |
- hormone receptor: GH
- prolactin
|
|
|
| Type II |
- Interleukin receptors
- IL10R / IL10RA / IL10RB / IL22R / IL22RA1 / IL22RA2
- IL20R / IL20RA / IL20RB
- IL28R
- Interferon receptors
- -α/β / IFNAR1/IFNAR2
- -γ/IFNGR1 / IFNGR2
|
|
|
| Ig superfamily |
- CSF1
- KIT
- IL1
- IL18R / IL18R1
|
|
| IL 17 family |
- IL17
- IL17RA
- IL17RB
- IL17RC
- IL17RD
- IL17RE
|
|
| S/T |
|
|
UpToDate Contents
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English Journal
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- PMID 28617055
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- Expert opinion on drug safety.Expert Opin Drug Saf.2017 Jun;16(6):733-742. doi: 10.1080/14740338.2017.1323864. Epub 2017 May 9.
- PMID 28441904
- Chlamydia pneumoniae induces interleukin-12 responses in peripheral blood mononuclear cells in asthma and the role of toll like receptor 2 versus 4: a pilot study.
- Smith-Norowitz TA1, Perlman J2, Norowitz YM2, Joks R3, Durkin HG4, Hammerschlag MR2, Kohlhoff S2.
- Irish journal of medical science.Ir J Med Sci.2017 May;186(2):511-517. doi: 10.1007/s11845-016-1549-9. Epub 2016 Dec 29.
- PMID 28035483
Japanese Journal
- Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection
- Tumoricidal efficacy coincides with CD11c up-regulation in antigen-specific CD8+ T cells during vaccine immunotherapy
- Journal of experimental & clinical cancer research 35, 143, 2016-09-13
- NAID 120005890036
- Interleukin-12B is upregulated by decoy receptor 3 in rheumatoid synovial fibroblasts
Related Links
- "Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4". Blood 95 (10): 3183–90. PMID 10807786. ^ Temblay JN, Bertelli E, Arques JL, Regoli M . ...
- Detailed information about IL-12 family, IL-12 functions, and antitumor roles. Sino biological offers a range of high-quality proteins and antibodies for research on IL-12 family ligands, IL-12 family receptors and IL-12 family signaling. ...
★リンクテーブル★
[★]
- 関
- interleukin-12 receptor
[★]
- 英
- interleukin-12 receptor、IL-12 receptor
- 関
- IL-12受容体、IL-12レセプター
[★]
[★]
[★]
インターロイキン IL
[★]
インターロイキン IL