イノシトール二リン酸、イノシトール2リン酸
- 関
- IP2
WordNet
- an optically inactive alcohol that is a component of the vitamin B complex
UpToDate Contents
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- 1. 血小板生物学platelet biology [show details]
…hydrolysis pathway begins when phospholipase C cleaves membrane phosphatidylinositol 4,5-bisphosphate (PIP2) to form inositol 1,4,5-trisphosphate (IP3) and diacylglycerol, both of which serve as second messengers …
- 2. 肥満細胞:表面受容体とシグナル伝達mast cells surface receptors and signal transduction [show details]
…activated PLC cleaves phosphatidylinositol-derived inositol 4,5 bisphosphate (PIP2) to generate the second messengers diacylglycerol (DAG) and inositol 1,4,5 triphosphate (IP3) . DAG activates protein kinase…
- 3. T細胞受容体シグナル伝達t cell receptor signaling [show details]
… activating this survival promoting pathway . PLC-gamma-1 cleaves phosphatidylinositol(4,5)bisphosphate into DAG and inositol triphosphate (IP3). Membrane-bound DAG activates members of the PKC family, in particular…
- 4. 獲得免疫である体液性免疫応答the adaptive humoral immune response [show details]
…(PLC-gamma-2), which can then hydrolyze the membrane phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into inositol triphosphate (IP3) and diacylglycerol (DAG). IP3 and DAG lead to downstream …
- 5. 移植免疫transplantation immunobiology [show details]
…minutes of T-cell receptor (TCR) engagement, membrane-bound phosphatidylinositol 4,5-bisphosphate (PIP) is hydrolyzed to inositol triphosphate (IP3) and diacylglycerol (DAG). The increase in IP3 causes the endoplasmic …
English Journal
- Role of lysosomal channel protein TPC2 in osteoclast differentiation and bone remodeling under normal and low-magnesium conditions.
- Notomi T1,2,3, Kuno M4, Hiyama A3, Nozaki T3, Ohura K3, Ezura Y5, Noda M6,2,7.
- The Journal of biological chemistry.J Biol Chem.2017 Dec 22;292(51):20998-21010. doi: 10.1074/jbc.M117.780072. Epub 2017 Oct 30.
- PMID 29084844
- A membrane-associated, fluorogenic reporter for mammalian phospholipase C isozymes.
- Huang W1, Wang X1, Endo-Streeter S2, Barrett M2, Waybright J1, Wohlfeld C2, Hajicek N2, Harden TK1, Sondek J3, Zhang Q2.
- The Journal of biological chemistry.J Biol Chem.2017 Dec 20. pii: jbc.RA117.000926. doi: 10.1074/jbc.RA117.000926. [Epub ahead of print]
- PMID 29263090
- Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy.
- Ben-Salem S#1, Robbins SM#2, Lm Sobreira N2, Lyon A3, Al-Shamsi AM4, Islam BK5, Akawi NA6, John A1, Thachillath P5, Al Hamed S5, Valle D2, Ali BR1, Al-Gazali L5.
- Journal of medical genetics.J Med Genet.2017 Nov 9. pii: jmedgenet-2017-104827. doi: 10.1136/jmedgenet-2017-104827. [Epub ahead of print]
- PMID 29122926
Japanese Journal
- TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2
- A Novel <i>OCRL1</i> Mutation in a Patient with the Mild Phenotype of Lowe Syndrome
- Phospholipase Cε as a potential molecular target for anti-inflammatory therapy and cancer prevention
Related Links
- Inositol phosphates are important intracellular second messengers in eukaryotic cells. Inositol, a cyclic molecule with six hydroxyl groups, forms the hydrophobic head group of membrane inositol phospholipids. The ...
- Inositol usually refers to Myo-inositol, a small molecule structurally similar to glucose that is involved in cellular signalling. It appears to be an effective anxiolytic at higher doses, and is quite effective in treating insulin resistance and ...
Related Pictures
★リンクテーブル★
[★]
- 英
- inositol bisphosphate、IP2
- 関
- イノシトール2リン酸
[★]
- 英
- inositol bisphosphate
- 関
- イノシトール二リン酸
[★]
二リン酸エステル、二リン酸
- 関
- diphosphate、diphosphoric acid、pyrophosphate
[★]
イノシトール
- 関
- myoinositol