English Journal

Characterization and immunomodulatory activity of polysaccharides derived from Dendrobium tosaense.

Yang LC1, Lu TJ2, Hsieh CC3, Lin WC4.
Carbohydrate polymers.Carbohydr Polym.2014 Oct 13;111:856-63. doi: 10.1016/j.carbpol.2014.05.007. Epub 2014 May 14.
Dendrobium tosaense is a medicinal Dendrobium species widely used in traditional medicine. This study demonstrated some structural characterizations and immunomodulatory activity of the water-soluble polysaccharides derived from the stem of D. tosaense (DTP). DTP was fractioned using DEAE-650 M anio
PMID 25037425

Preserving learned immunosuppressive placebo response: perspectives for clinical application.

Albring A1, Wendt L1, Benson S1, Nissen S1, Yavuz Z1, Engler H1, Witzke O2, Schedlowski M1.
Clinical pharmacology and therapeutics.Clin Pharmacol Ther.2014 Aug;96(2):247-55. doi: 10.1038/clpt.2014.75. Epub 2014 Apr 3.
Akin to other physiological responses, immune functions can be modified through behavioral conditioning as part of a learned placebo response. However, like every learning process, learned immune responses are subject to extinction. We analyzed the extinction of learned immunosuppression in healthy
PMID 24699032

Borriello F1, Granata F1, Varricchi G1, Genovese A1, Triggiani M2, Marone G3.
Current opinion in pharmacology.Curr Opin Pharmacol.2014 Jul 23;17C:45-57. doi: 10.1016/j.coph.2014.07.002. [Epub ahead of print]
Mast cells produce a wide spectrum of mediators and they have been implicated in several physiopathological conditions (e.g. allergic reactions and certain tumors). Pharmacologic agents that modulate the release of mediators from mast cells has helped to elucidate the biochemical mechanisms by which
PMID 25063971

Japanese Journal

Baicalin From Scutellaria baicalensis Impairs Th1 Polarization Through Inhibition of Dendritic Cell Maturation

, , [他], , ,
Journal of Pharmacological Sciences 121(2), 148-156, 2013
… These findings provide important understanding of the immunopharmacological functions of baicalin and have ramifications for the development of therapeutic adjuvants for the treatment of DCs-related acute and chronic diseases. …
NAID 130003362673

岡井康二,岡田岳大,岡井(東) 紀代香 [他],笠原恵美子,井上正康,山下優毅
産業医科大学雑誌 31(3), 231-242, 2009-09-01
日本産赤米,黒米,白米それぞれのぬか抽出液中に存在する免疫調節活性についてマウスの免疫細胞の培養システムを用いて分析した.これらのコメぬかのメタノール抽出液はコンカナバリンA(Con A)やリポポリサッカライド(LPS)によるマウス脾臓リンパ球の増殖反応を有意に抑制した.しかし,同様のリンパ球の培養システムにおける炎症性サイトカインの産生に対する影響を調べたところ,赤米ぬか抽出液は,Con Aによ …
NAID 110007339730