- n.
- 免疫除去
- Immunoablation alone — Immunoablation without bone marrow or stem cell support has also been effective in some patients with moderate to severe SLE refractory to glucocorticoids and immunosuppressive therapy(免疫除去単独：骨髄や幹細胞をサポートしない免疫除去も、糖質コルチコイド療法や免疫抑制療法に反応しない中程度から重度のSLE患者に有効を示す場合がある)
目次
WordNet
- surgical removal of a body part or tissue (同)extirpation, cutting out, excision
- the erosive process that reduces the size of glaciers
PrepTutorEJDIC
- 切除,除去;融除 / 溶発(ロケットの先端が大気圏突入で溶解すること)
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 重度の複合免疫不全症での造血細胞移植hematopoietic cell transplantation for severe combined immunodeficiencies [show details]
- 2. 若年性全身性硬化症（強皮症）：評価および治療のアプローチjuvenile systemic sclerosis scleroderma assessment and approaches to treatment [show details]
- 3. 多発性硬化症の疾患修飾療法：薬理学、投与法、副作用disease modifying therapies for multiple sclerosis pharmacology administration and adverse effects [show details]
English Journal
- CAR-T "the living drugs", immune checkpoint inhibitors, and precision medicine: a new era of cancer therapy.
- , L L, D D, D D, .
- Journal of hematology & oncology. 2019 Nov;12(1)113.
- New advances in the design and manufacture of monoclonal antibodies, bispecific T cell engagers, and antibody-drug conjugates make the antibody-directed agents more powerful with less toxicities. Small molecule inhibitors are routinely used now as oral targeted agents for multiple cancers. The disco
- PMID 31703740
- Autologous hematopoietic stem cell transplantation improves fatigue in multiple sclerosis.
- Bose G, Atkins HL, Bowman M, Freedman MS.
- Multiple sclerosis (Houndmills, Basingstoke, England). 2019 Nov;25(13)1764-1772.
- Fatigue is a common problem in multiple sclerosis (MS) affecting as many as 90% of patients. The Fatigue Impact Scale (FIS) is a validated measure of fatigue in MS patients. The cause of fatigue in MS is likely multifactorial, with some evidence that ongoing central nervous system (CNS) inflammation
- PMID 30251913
- High serum neurofilament light chain normalizes after hematopoietic stem cell transplantation for MS.
- Thebault S, R Tessier D, Lee H, Bowman M, Bar-Or A, Arnold DL, L Atkins H, Tabard-Cossa V, Freedman MS.
- Neurology(R) neuroimmunology & neuroinflammation. 2019 Sep;6(5)e598.
- To evaluate neurofilament light chain (NfL) levels in serum and CSF of patients with aggressive MS pre- and post-treatment with immunoablation followed by autologous hematopoietic stem cell transplantation (IAHSCT) and examine associations with clinical and MRI outcomes. Paired serum and CSF in addi
- PMID 31516913
Related Links
- immunoablation: (ĭm-ū″-nō-ă-blā′shŭn) The systematic destruction of a patient's immune competence. Immunoablation is used to prepare patients for organ transplantation and to treat refractory autoimmune diseases, esp. when followed by immunoreconstruction (usually with autologous stem cell transplantation). Patient care Patients who have ...
- Immunoablation with busulfan, cyclophosphamide, and rabbit anti-thymocyte globulin was followed by aHSCT. The primary outcome was multiple sclerosis activity-free survival (events were clinical relapse, appearance of a new or , . ...
- Over the past 20 years, immunoablation followed by transplantation of autologous haematopoietic stem cells (ASCT) has emerged as a promising treatment option for patients with severe forms of autoimmune diseases (ADs) that insufficiently respond to standard immunosuppressive or novel biologic treatm …
Related Pictures
