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Patient characteristics and outcomes associated with nitrovasodilator use in the treatment of acute heart failure.

Pang PS1, Goren A, Kopenhafer L, Park J.
American journal of therapeutics.Am J Ther.2015 May-Jun;22(3):206-13. doi: 10.1097/MJT.0000000000000211.
Nitrovasodilators (NVs) are commonly recommended for the treatment of acute heart failure (AHF); however, registries suggest their use is not common. The objectives of this study were to determine patient characteristics associated with NV use and to explore the association between NV use and outcom
PMID 25650530

Agreement between whole blood and plasma sodium measurements in profound hyponatremia.

Geoghegan P1, Koch CD2, Wockenfus AM2, Harrison AM3, Dong Y4, Kashani KB5, Karon BS2.
Clinical biochemistry.Clin Biochem.2015 May;48(7-8):525-8. doi: 10.1016/j.clinbiochem.2015.03.001. Epub 2015 Mar 13.
OBJECTIVES: We compared two different methods of whole blood sodium measurement to plasma sodium measurement using samples in the profoundly hyponatremic range (Na<120mmol/L).DESIGN AND METHODS: Whole blood pools with a range of low sodium values were generated using combinations and dilutions of
PMID 25773258

Hyponatremia and poor cognitive outcome following pediatric brain tumor surgery.

Williams CN1, Riva-Cambrin J, Presson AP, Bratton SL.
Journal of neurosurgery. Pediatrics.J Neurosurg Pediatr.2015 May;15(5):480-7. doi: 10.3171/2014.10.PEDS14368. Epub 2015 Feb 27.
OBJECT Pediatric intracranial neoplasms are common and cause substantial neurological morbidity. Postoperative hyponatremia is also common and may exacerbate neurological injury. The authors performed an exploratory analysis to evaluate an exposure-response relationship between hyponatremia severity
PMID 25723724

Urine Sodium Excretion After Tolvaptan Administration Is Dependent Upon Baseline Serum Sodium Levels:A Possible Explanation for the Improvement of Hyponatremia With Scarce Chance of Hypernatremia by a Vasopressin Receptor Antagonist

Imamura Teruhiko,Kinugawa Koichiro,Minatsuki Shun,Muraoka Hironori,Kato Naoko,Inaba Toshiro,Maki Hisataka,Hatano Masaru,Yao Atsushi,Komuro Issei
International Heart Journal 55(2), 131-137, 2014
… In hyponatremic responders (n = 25), S-Na increased significantly, although 1 week was not sufficient for normalization (125.8 ± 5.0 versus 128.9 ± 4.3 mEq/L, P < … 0.05).TLV increased S-Na only in hyponatremic responders by way of pure aquaresis, but increased U-NaEx24 only in normonatremic responders, which explains the scarcity of hypernatremia. …
NAID 130003392071

Hyponatremia is the valuable manifestation for initiating diagnosis of hypopituitarism in elderly

Asano Tomoko,Aoki Atsushi,Sasaki Masami,Ikoma Aki,Kakei Masahumi,Kawakami Masanobu,Ishikawa San-e
Endocrine Journal 59(11), 1015-1020, 2012
… There was no difference in serum cortisol levels between the hyponatremic and normonatremic patients. … Despite hypoosmolality, plasma arginine vasopressin (AVP) was apparently high in the hyponatremic patients compared with in the normonatremic ones. …
NAID 130004443763