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1. 黒色腫（メラノーマ）の分子生物学 the molecular biology of melanoma

English Journal

Non-apoptotic cell death associated with perturbations of macropinocytosis.

Maltese WA1, Overmeyer JH1.
Frontiers in physiology.Front Physiol.2015 Feb 16;6:38. doi: 10.3389/fphys.2015.00038. eCollection 2015.
Although macropinocytosis is widely recognized as a distinct form of fluid-phase endocytosis in antigen-presenting dendritic cells, it also occurs constitutively in many other normal and transformed cell types. Recent studies have established that various genetic or pharmacological manipulations can
PMID 25762935

CD28: direct and critical receptor for superantigen toxins.

Kaempfer R1, Arad G, Levy R, Hillman D, Nasie I, Rotfogel Z.
Toxins.Toxins (Basel).2013 Sep 9;5(9):1531-42. doi: 10.3390/toxins5091531.
Every adaptive immune response requires costimulation through the B7/CD28 axis, with CD28 on T-cells functioning as principal costimulatory receptor. Staphylococcal and streptococcal superantigen toxins hyperstimulate the T-cell-mediated immune response by orders of magnitude, inducing a lethal cyto
PMID 24022021

Focal brain inflammation and autism.

Theoharides TC1, Asadi S, Patel AB.
Journal of neuroinflammation.J Neuroinflammation.2013 Apr 9;10:46. doi: 10.1186/1742-2094-10-46.
Increasing evidence indicates that brain inflammation is involved in the pathogenesis of neuropsychiatric diseases. Autism spectrum disorders (ASD) are characterized by social and learning disabilities that affect as many as 1/80 children in the USA. There is still no definitive pathogenesis or reli
PMID 23570274

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