homopantothenic acid

ホモパントテン酸

WordNet

1. street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
2. any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
3. having the characteristics of an acid; "an acid reaction"

PrepTutorEJDIC

1. 酸性の / 酸味のある,すっぱい(sour) / (言葉・態度などが)厳しい,しんらつな / 酸 / すっぱいもの / 《俗》=LSD

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/15 15:39:24」(JST)

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Hopantenic acid

Names
IUPAC name 4-{[(2R)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino}butanoic acid
Identifiers
CAS Registry Number	18679-90-8 Y 17097-76-6 (Calcium salt) Y
ChemSpider	26309 Y
InChI InChI=1S/C10H19NO5/c1-10(2,6-12)8(15)9(16)11-5-3-4-7(13)14/h8,12,15H,3-6H2,1-2H3,(H,11,16)(H,13,14)/t8-/m0/s1 Y Key: SBBDHANTMHIRGW-QMMMGPOBSA-N Y
Jmol-3D images	Image Image
KEGG	D08042 Y
PubChem	28281
SMILES CC(C)(CO)[C@@H](O)c(:[o]):[nH]CCCc(:[o]):[oH] CC(C)(CO)[C@@H](O)C(=O)NCCCC(O)=O
Properties
Molecular formula	C10H19NO5
Molar mass	233.26 g·mol−1
Related compounds
Related alkanoic acids	Theanine Pantothenic acid 4-(γ-Glutamylamino)butanoic acid
Related compounds	Panthenol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Hopantenic acid (homopantothenic acid) is a central nervous system drug. Formulated as the calcium salt, it is used in the Russian Federation for a variety of neurological, psychological and psychiatric conditions and sold as Pantogam (Russian: Пантогам).

Chemistry

Hopantenic acid is a homolog of pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA). This change leads to an additional CH₂ in the molecule.

See also

• Methyl pentanoate
• Menthyl isovalerate

References

External links

• pantogab (hopantenic acid) - Curehunter.com

UpToDate Contents

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English Journal

• [Clinical and neurophysiological objectification and evaluation of treatment efficacy in children with perinatal hypoxic-ischemic injury of the CNS].

• Grebennikova OV, Zavadenko AN, Rogatkin SO, Medvedev MI, Degtiareva MG.
• Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov.Zh Nevrol Psikhiatr Im S S Korsakova.2014;114(4):63-7.
• OBJECTIVE: To objectify indications for treatment with pantogam in premature infants with perinatal hypoxic-ischemic injury of the CNS.MATERIAL AND METHODS: We studied 71 children, with GA (gestation age) 24-36 weeks (32,9±2,9 weeks), with perinatal hypoxic-ischemic injury of the CNS, I-II grades,
• PMID 24874320

• [Management of cognitive impairment in children and adolescents with cerebral palsy treated with pantocalcin].

• Batysheva TT1, Platonova AN, Chebanenko NV, Bykova OV.
• Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov.Zh Nevrol Psikhiatr Im S S Korsakova.2013;113(9):48-53.
• A randomized study on the efficacy and safety of the hopantenic acid preparation (pantocalcin) and its effect on cognitive functions in children with cerebral palsy (CCP) has been carried out. The positive effect of pantocalcin on the visual memory and attention concentration, activity and fatigabil
• PMID 24107880

• [Correction of early cognitive disorders in school-age children operated under total intravenous anaesthesia].

• Ovezov AM, Lobov MA, Panteleeva MV, Lugovoĭ AV, Miatchin PS, Gus'kov IE.
• Anesteziologiia i reanimatologiia.Anesteziol Reanimatol.2012 May-Jun;(3):25-9.
• The aim of the study was to assess the possibility and effectiveness of hopaten acid use for early postoperative cognitive dysfunction correction in children of school age.MATERIALS AND METHODS: In compliance with inclusion and exclusion criteria, totally 40 children of school age (7-16 years old, A
• PMID 22993919

Japanese Journal

• Effects of Homopantothenic Acid on Intestinal Smooth Muscles

• Fukushi Yasue,Suzuki Tsunehiko
• Tohoku Journal of Experimental Medicine 140(1), p45-51, 1983-05
• NAID 40005307064

• 幼若シロネズミの肝Coenzyme A代謝に及ぼすパントテン酸, パンテチン, Coenzyme A投与の影響

• 辻田 賢三
• ビタミン 46(5), 255-260, 1972-11-25
• … There was no difference between the effects of injection of pantothenic acid (PaA), pantethine (PaSS) or CoA on the hepatic CoA content in PaA deficient rats. … The decreased content of CoA in homopantothenic acid administered or protein deficient rat liver was recoverd by the injection of PaA, PaSS or CoA. …
• NAID 110002850770

• Homopantothenic acidのニワトリにおよぼす影響について (パントテン酸および類縁物質に関する研究-1,2-)

• 黒牧 武夫
• 昭和医学会雑誌 31(3), 138-145, 1971
• Die Applikation von Homopantothensäure (Pantoyl-γ-aminobuttersäure) an erwachsenen Hühnern and befruchteten Hühnereiern kam zu folgenden Ergebnissen.<BR>1) Die wässerige Lösung des Ca-Salzes von …
• NAID 130001820034

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★リンクテーブル★

リンク元

「ホパンテン酸」

「ホパンテン酸」

　　[★]

英

hopantenic acid

同

ホモパントテン酸 homopantothenic acid

化

ホパンテン酸カルシウム calcium hopantenate

商

ホパテ

• 脳代謝賦活薬