ホメオティックな、相同異質形成の
- 関
- homeosis
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/06 13:10:08」(JST)
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Homeosis is the transformation of one organ into another, arising from mutation in or misexpression of specific developmentally critical genes. In animals, these developmental genes specifically control the development of organs on their anteroposterior axis.[1] In plants, however, the developmental genes affected by homeosis may control anything from the development of a stamen or petals to the development of chlorophyll.[2] Homeosis may be caused by mutations in Hox genes, found in animals, or others such as the MADS-box family in plants. Homeosis is a characteristic that has helped insects become as successful and diverse as they are.[3]
Homeotic mutations work by changing segment identity during development. For example, the Ultrabithorax genotype gives a phenotype wherein metathoracic and first abdominal segments become mesothoracic segments.[4] Another well-known example is Antennapedia: a gain-of-function allele causes legs to develop in the place of antennae.[5]
In botany, Rolf Sattler has revised the concept of homeosis (replacement) by his emphasis of partial homeosis in addition to complete homeosis, which is commonly accepted.[6]
Homeotic mutants in angiosperms are thought to be rare in the wild: in the annual plant Clarkia, (Onagraceae), homeotic mutants are known where the petals are replaced by a second whorl of sepal like organs, originating via a mutation governed by a single recessive gene.[7] The absence of lethal or deleterious consequences in floral mutants resulting in distinct morphological expressions has been a factor in the evolution of Clarkia, and perhaps also in many other plant groups.[8]
See also
- Homeotic gene, includes most of the hox genes
- Homeobox, a DNA segment found in hox genes
References
- ^ Hombría, James Castelli-Gair; Lovegrove, Bridget (2003-10-01). "Beyond homeosis—HOX function in morphogenesis and organogenesis". Differentiation 71 (8): 461–476. doi:10.1046/j.1432-0436.2003.7108004.x. ISSN 1432-0436.
- ^ Sattler, Rolf (October 1998). "Homeostasis in Plants". American Journal of Botany 75: 1606–1617. doi:10.2307/2444710. Retrieved 24 September 2015.
- ^ Lodish et al., 2003. Molecular Cell Biology, 5th Edition. W.H. Freeman and Company, New York.[page needed]
- ^ Nüsslein-Volhard, Christiane; Wieschaus, Eric (1980). "Mutations affecting segment number and polarity in Drosophila". Nature 287 (5785): 795–801. doi:10.1038/287795a0. PMID 6776413.
- ^ Schneuwly, Stephan; Klemenz, Roman; Gehring, Walter J. (1987). "Redesigning the body plan of Drosophilaby ectopic expression of the homoeotic gene Antennapedia". Nature 325 (6107): 816–818. doi:10.1038/325816a0. PMID 3821869.
- ^ Sattler, R. (1988). "Homeosis in Plants". American Journal of Botany 75 (10): 1606–1617. doi:10.2307/2444710. JSTOR 2444710.
- ^ Ford, V. S.; Gottlieb, L. D. (1992). "Bicalyx is a natural homeotic floral variant". Nature 358 (6388): 671–673. doi:10.1038/358671a0.
- ^ Gottlieb, L. D. (1984). "Genetics and Morphological Evolution in Plants". The American Naturalist 123 (5): 681–709. doi:10.1086/284231. JSTOR 2461245.
English Journal
- The role of complement in C3 glomerulopathy.
- Zipfel PF1, Skerka C2, Chen Q2, Wiech T3, Goodship T4, Johnson S4, Fremeaux-Bacchi V5, Nester C6, Córdoba SR7, Noris M8, Pickering M9, Smith R6.
- Molecular immunology.Mol Immunol.2015 Sep;67(1):21-30. doi: 10.1016/j.molimm.2015.03.012. Epub 2015 Apr 28.
- C3 glomerulopathy describes a spectrum of disorders with glomerular pathology associated with C3 cleavage product deposition and with defective complement action and regulation (Fakhouri et al., 2010; Sethi et al., 2012b). Kidney biopsies from these patients show glomerular accumulation or depositio
- PMID 25929733
- A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra.
- Glauber KM, Dana CE, Park SS, Colby DA, Noro Y, Fujisawa T, Chamberlin AR, Steele RE.
- Development (Cambridge, England).Development.2015 Jun 1;142(11):2081. doi: 10.1242/dev.126235.
- PMID 26015540
- Towards the resolution of a long-standing evolutionary question: muscle identity and attachments are mainly related to topological position and not to primordium or homeotic identity of digits.
- Diogo R1, Walsh S1, Smith C2, Ziermann JM1, Abdala V3.
- Journal of anatomy.J Anat.2015 Jun;226(6):523-9. doi: 10.1111/joa.12301. Epub 2015 Apr 7.
- Signaling for limb bone development usually precedes that for muscle development, such that cartilage is generally present before muscle formation. It remains obscure, however, if: (i) tetrapods share a general, predictable spatial correlation between bones and muscles; and, if that is the case, if
- PMID 25851747
Japanese Journal
- In cut tail reproduction model, its reformation according to Homeotic genes, tumor production and its detection by immune system (第13回生物数学の理論とその応用 : 連続および離散モデルのモデリングと解析)
- 花の形づくりを決める遺伝子ネットワーク : シロイヌナズナ花研究のこれまでとこれから
- Floral Morphology and MADS Gene Expression in Double-flowered Japanese Evergreen Azalea
★リンクテーブル★
[★]
- 英
- homeosis、homeotic
- 関
- ホメオシス、ホメオティック
[★]
ホメオシス、相同異質形成
- 関
- homeotic
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- 英
- homeotic
- 関
- 相同異質形成
[★]
ホメオティック遺伝子、ホメオ遺伝子
- 関
- homeo box、homeobox、homeobox gene
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ホメオティッククラスター