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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/11/16 13:49:08」(JST)

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Histaminergic, or histaminic, means "related to histamine".

A histaminergic agent (or drug) is a chemical which functions to directly modulate the histamine system in the body or brain. Examples include histamine receptor agonists and histamine receptor antagonists (or antihistamines). Subdivisions of histamine antagonists include H₁ receptor antagonists, H₂ receptor antagonists, and H₃ receptor antagonists.

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English Journal

IV nicotine self-administration in rats using a consummatory operant licking response: Sensitivity to serotonergic, glutaminergic and histaminergic drugs.

Cousins V1, Rose JE1, Levin ED2.
Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2014 Oct 3;54:200-5. doi: 10.1016/j.pnpbp.2014.06.004. Epub 2014 Jun 20.
Tobacco smoking is characterized by repeated self-administration of nicotine by placing the cigarette in the mouth. The repeated hand-to-mouth self-administration is essentially a consummatory act. We recently developed a paradigm in which rats lick one of two spouts to trigger intravenous (IV) deli
PMID 24953434

Betahistine ameliorates olanzapine-induced weight gain through modulation of histaminergic, NPY and AMPK pathways.

Lian J1, Huang XF2, Pai N3, Deng C4.
Psychoneuroendocrinology.Psychoneuroendocrinology.2014 Oct;48:77-86. doi: 10.1016/j.psyneuen.2014.06.010. Epub 2014 Jun 18.
Olanzapine is widely used to treat schizophrenia and other disorders, but causes adverse obesity and other metabolic side-effects. Both animal and clinical studies have shown that co-treatment with betahistine (a histaminergic H1 receptor agonist and H3 receptor antagonist) is effective for ameliora
PMID 24992721

Metabotropic glutamate receptors inhibit GABA release in rat histamine neurons.

Jang IS.
Neuroscience letters.Neurosci Lett.2014 Sep 5;579:106-9. doi: 10.1016/j.neulet.2014.07.022. Epub 2014 Jul 22.
The modulation of GABAergic transmission by metabotropic glutamate (mGlu) receptors was examined in histaminergic neurons using a conventional whole-cell patch clamp technique. DHPG, a selective group I mGlu receptor agonist, had no effect on GABAergic inhibitory postsynaptic currents (IPSCs). Howev
PMID 25062585

Japanese Journal

Changes in the electroencephalogram caused by intravenous administration of modafinil under sevoflurane anesthesia in rats

Kano Seiji,Matsuda Yoshiko,Kotani Junihciro
Journal of Osaka Dental University 46(1), 1-4, 2012-04-00
… Modafinil, a drug for the treatment of hypersomnia and narcolepsy, activates dopaminergic neurons and histaminergic neurons and inhibits the release of gamma-aminobutyric acid to enhance awakening from natural sleep. …
NAID 110009436530

The Effect of Antihistamines on Seizures Induced by Increasing-Current Electroshocks: Ketotifen, but Not Olopatadine, Promotes the Seizures in Infant Rats

Yamada Koji,Takizawa Fumitake,Tamura Tadafumi [他],Kanda Tomoyuki
Biological and Pharmaceutical Bulletin 35(5), 693-697, 2012
… These results showed that histaminergic neuro-transmission in the brain plays a crucial role in inhibiting seizures in rats soon after weaning, but is no longer effective in rats as they approach sexual maturation. …
NAID 130001872226

Carnosine Ameliorates Stress-Induced Glucose Metabolism Disorder in Restrained Mice

Tsoi Bun,He Rong-Rong,Yang Dong-Hui [他],LI Yi-Fang,LI Xiao-Di,LI Wei-Xi,ABE Keiichi,KURIHARA Hiroshi
Journal of pharmacological sciences 117(4), 223-229, 2011-12-20
… It is presumable that carnosine exerts its anti-stress effects by indirectly affecting the histaminergic neuron system, modulating the stress-activated hypothalamic–pituitary–adrenal axis and improving glucose metabolism through regulation of the enzymes in the glucose metabolic pathways. …
NAID 10030453555