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English Journal

Davila J1, Manwani D2, Vasovic L3, Avanzi M4, Uehlinger J3, Ireland K2, Mitchell WB4,5.
Platelets.Platelets.2015 Dec;26(8):726-9. doi: 10.3109/09537104.2014.983891. Epub 2014 Dec 30.
The severe pain, ischemia and organ damage that characterizes sickle cell disease (SCD) is caused by vaso-occlusion, which is the blockage of blood vessels by heterotypic aggregates of sickled erythrocytes and other cells. Vaso-occlusion is also a vasculopathy involving endothelial cell dysfunction,
PMID 25548984

Tandem truncated rotavirus VP8* subunit protein with T cell epitope as non-replicating parenteral vaccine is highly immunogenic.

Wen X1, Cao D2, Jones RW3, Hoshino Y3, Yuan L2.
Human vaccines & immunotherapeutics.Hum Vaccin Immunother.2015 Oct 3;11(10):2483-9. doi: 10.1080/21645515.2015.1054583.
The two currently available live oral rotavirus vaccines, Rotarix(®) and RotaTeq(®), are highly efficacious in the developed countries. However, the efficacy of such vaccines in resource deprived countries in Africa and Southeast Asia is low. We reported previously that a bacterially-expressed rot
PMID 26091081

Tumor Microenvironments: Rapid 3D Extrusion of Synthetic Tumor Microenvironments (Adv. Mater. 37/2015).

Grolman JM1, Zhang D1, Smith AM2, Moore JS1,3, Kilian KA1,2.
Advanced materials (Deerfield Beach, Fla.).Adv Mater.2015 Oct;27(37):5445. doi: 10.1002/adma.201570242.
The generation of cell-laden spatially organized 3D hydrogels is demonstrated by K. A. Kilian and co-workers on page 5512, using macrophages and breast adenocarcinoma cells as a heterotypic model that mimics aspects of the tumor microenvironment. This versatile and tunable approach for fabricating s
PMID 26426720