眼部帯状ヘルペス
WordNet
- of or relating to the eye; "ophthalmic defect"
- of or relating to ophthalmology; "ophthalmic surgery"
- viral diseases causing eruptions of the skin or mucous membrane
- any of the animal viruses that cause painful blisters on the skin (同)herpes_virus
PrepTutorEJDIC
- 目の,眼科の,眼炎の
- 疱疹(ほうしん)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/28 01:52:23」(JST)
[Wiki en表示]
Ophthalmic zoster |
Herpes zoster ophthalmicus
|
Classification and external resources |
Specialty |
Infectious disease |
ICD-10 |
B02 |
ICD-9-CM |
053.20 |
DiseasesDB |
29119 |
MedlinePlus |
000858 |
eMedicine |
med/1007 derm/180 emerg/823 oph/257 ped/996 |
[edit on Wikidata]
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Herpes zoster ophthalmicus (HZO) and also known as ophthalmic zoster is a disease characterised by reactivation of dormant varicella zoster virus residing within the ophthalmic nerve (the first division of the trigeminal nerve).[1]:380[2] This condition is an important subtype of shingles, representing 15% of all cases.[3] Herpes zoster ophthalmicus is transmitted via direct contact or droplets. Varicella zoster virus is a DNA virus which produces acidophilic intranuclear inclusion bodies. The virus is neurotrophic in nature.
The frontal nerve is more commonly affected than the nasociliary nerve or lacrimal nerve.[4]
Contents
- 1 Signs and symptoms
- 1.1 Skin
- 1.2 Cornea
- 1.3 Uveal
- 2 Treatment
- 3 References
Signs and symptoms
Any potential ocular involvement should be assessed by an ophthalmologist as complications such as episcleritis and uveitis may occur.
Skin
- Viral prodrome
- Preherpetic neuralgia
- Rash, transitioning from papules to vesicles to pustules to scabs.
- Hutchinson's sign: cutaneous involvement of the tip of the nose, indicating nasociliary nerve involvement. A positive Hutchinson's sign increases the likelihood of ocular complications associated with HZO.
- Disseminated distribution in individuals with immunodeficiency.[3]
Cornea
See also: Cornea § Layers
- Epithelial: punctate epithelial erosions and pseudodendrites: often have anterior stromal infiltrates. Onset 2 to 3 days after the onset of the rash, resolving within 2–3 weeks. Common.
- Stromal:
- Nummular keratitis: have anterior stromal granular deposits. Occurs within 10 days of onset of rash. Uncommon
- Necrotising interstitial keratitis: Characterised by stromal infiltrates, corneal thinning and possibly perforation. Occurs between 3 months and several years after onset of rash. Rare.
- Disciform Keratitis(Disciform Endotheliitis): a disc of corneal oedema, folds in Descemet's membrane, mild inflammation evident within the anterior chamber and fine keratic precipitates. Chronic. Occurs between 3 months and several years after the onset of the rash. Uncommon.
- Neurotrophic: corneal nerve damage causes persistent epithelial defect, thinning and even perforation. Cornea becomes susceptible to bacterial and fungal keratitis. Chronic. Late onset. Uncommon.
- Mucous plaques: linear grey elevations loosely adherent to the underlying diseased epithelium/stroma. Chronic. Onset between 3 months and several years after the onset of the rash.[3]
Uveal
Anterior uveitis develops in 40–50% of cases with HZO within 2 weeks of onset of the skin rashes. Typical HZO keratitis at least mild iritis, especially if Hutchinson's sign is positive for the presence of vescicles upon the tip of the nose.
Features:[4]
This non-granulomatous iridocyclitis is associated with:
- Small keratic precipitates
- Mild aqueous flare
- Occasionally haemorrhagic hypopion.
HZO uveitis is associated with complications such as iris atrophy and secondary glaucoma are not uncommon. Complicated cataract may develop in the late stages of the disease.
Treatment
Treatment is usually with antivirals such as aciclovir orally.
Uveal
- Topical steroids and cycloplegics for several months.
- Systemic Aciclovir facilitates the early control of HZO lesions.[4]
References
- ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ a b c "Oxford Handbook of Ophthalmology". google.com.au.
- ^ a b c "Comprehensive Ophthalmology". google.com.au.
UpToDate Contents
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- 1. 帯状疱疹の疫学、臨床症状、診断epidemiology clinical manifestations and diagnosis of herpes zoster [show details]
…herpes zoster vaccine are less likely to develop PHN, even if herpes zoster occurs. Herpes zoster ophthalmicus (HZO) , a potentially sight-threatening condition, is defined as herpes zoster involvement …
- 2. 免疫正常患者における帯状疱疹の治療treatment of herpes zoster in the immunocompetent host [show details]
…In addition, there may be a role for adjunctive glucocorticoids in certain conditions. Herpes zoster ophthalmicus, a serious sight-threatening condition, has been linked to varicella zoster virus (VZV) …
- 3. 強膜炎の臨床症症状および診断clinical manifestations and diagnosis of scleritis [show details]
…polychondritis (3 percent). An infectious disease was present in 8 percent. These included herpes zoster ophthalmicus (5 percent), herpes simplex (2 percent), human immunodeficiency virus (2 percent), and…
- 4. 病院における水痘・帯状疱疹ウイルスの予防および管理prevention and control of varicella zoster virus in hospitals [show details]
…in a seropositive clinician 14 days after examination of an immunocompetent patient with herpes zoster ophthalmicus . The clinician wore gloves at the time of the encounter but did lift bandages to examine…
- 5. 水痘帯状疱疹ウイルスによる血管炎varicella zoster virus vasculopathy [show details]
…granulomatous aortitis. A subset of patients can have specific ocular and motor findings known as herpes zoster ophthalmicus with delayed contralateral hemiparesis. Intracerebral VZV vasculopathy can occur in patients …
English Journal
- Treatment of Pseudodendrites in Herpes Zoster Ophthalmicus With Topical Ganciclovir 0.15% Gel.
- Aggarwal S, Cavalcanti BM, Pavan-Langston D.SourceDepartment of Ophthalmology, *Cornea and Refractive Surgery Service; and †Ocular Surface Imaging Center, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA.
- Cornea.Cornea.2013 Dec 6. [Epub ahead of print]
- PURPOSE:: There is no standard of treatment for epithelial pseudodendrites in herpes zoster ophthalmicus (HZO). The purpose of this study is to report the topical antiviral drug, 0.15% ganciclovir for treatment of these lesions.METHODS:: This is a retrospective, interventional case series of 4 patie
- PMID 24322809
- Tinea atypica: report of nine cases.
- Zisova LG, Dobrev HP, Tchernev G, Semkova K, Aliman AA, Chorleva KI, Chapanova AT, Vutova NI, Wollina U.SourceDermatology and Venereology Department, Medical University, Plovdiv, Bulgaria, lzisova@abv.bg.
- Wiener medizinische Wochenschrift (1946).Wien Med Wochenschr.2013 Dec;163(23-24):549-555. Epub 2013 Aug 15.
- Fungal infections of the skin are a common condition, usually easy to diagnose and treat. When the infection is clinically mimicking another cutaneous disorder or when the clinical presentation is modified by the use of inappropriate treatment, it is referred to as tinea atypica or tinea incognito.W
- PMID 23949566
- Cluster headache after cataract surgery.
- Gil-Gouveia R, Fonseca A.Source*Headache Outpatient Clinic, Hospital da Luz †Department of Ophthalmology, Hospital de Santa Maria, Lisboa, Portugal.
- The Clinical journal of pain.Clin J Pain.2013 Nov;29(11):e19-21. doi: 10.1097/AJP.0b013e31828b10e9.
- BACKGROUND: Symptomatic cluster-like headache has been described with some ophthalmological disorders such as glaucoma, orbital myositis, posterior scleritis, enucleation, herpes zoster ophthalmicus, and cataract surgery.CASE REPORT: We report a new case of a 79-year-old nonsmoker woman who develope
- PMID 23486235
Japanese Journal
- 皮疹の治癒から4ヶ月後に発症した水痘-帯状疱疹ウイルス血管症による若年性脳梗塞の1例
- 眼球運動障害をきたした眼部帯状疱疹の1例 (第70回 日本臨床眼科学会講演集(4))
- 皮疹に1週間先行して頭痛と複視が出現した眼部帯状疱疹の1例
Related Links
- Herpes Zoster Ophthalmicus (HZO), commonly known as shingles, is a viral disease characterized by a painful skin rash in one or more dermatome distributions of the fifth cranial nerve, shared by the eye and orbit.
- Herpes zoster ophthalmicus is reactivation of a varicella-zoster virus infection (shingles) involving the eye. Symptoms and signs, which might be extreme, include dermatomal forehead rash and uncomfortable swelling of all the tissues ...
- Herpes zoster ophthalmicus is reactivation of a varicella-zoster virus infection involving the eye. Symptoms and signs, which may be severe, include dermatomal forehead rash and painful inflammation of all the tissues ...
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