関: VP16 protein

WordNet

unornamented; "a simple country schoolhouse"; "her black dress--simple to austerity"
any herbaceous plant having medicinal properties
(botany) of leaf shapes; of leaves having no divisions or subdivisions (同)unsubdivided
having few parts; not complex or complicated or involved; "a simple problem"; "simple mechanisms"; "a simple design"; "a simple substance"
a harmful or corrupting agency; "bigotry is a virus that must not be allowed to spread"; "the virus of jealousy is latent in everyone"
(virology) ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein
a software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer; "a true virus cannot spread to another computer without human assistance" (同)computer virus
having only one part or element; "a simplex word has no affixes and is not part of a compound--like `boy compared with `boyish or `house compared with `houseboat"
allowing communication in only one direction at a time, or in telegraphy allowing only one message over a line at a time; "simplex system"
any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
viral diseases causing eruptions of the skin or mucous membrane
any of the animal viruses that cause painful blisters on the skin (同)herpes_virus

PrepTutorEJDIC

『簡単な』容易な,分かりやすい / (複合に対して)単一の / 『単純な』,込み入っていない / 『純然たる』,全くの / 『飾り気のない』,簡素な,地味な,質素な / 『もったいぶらない』;誠実な,実直な / お人よしの,だまされやすい / 《文》地位のない,普通の,平(ひら)の
薬草,薬用植物
ビールス,ろ過性病原体
蛋白(たんばく)質
疱疹(ほうしん)

UpToDate Contents

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1. 新生児単純ヘルペスウイルス感染：臨床的特徴および診断 neonatal herpes simplex virus infection clinical features and diagnosis
2. 性器単純ヘルペスウイルス感染と妊娠 genital herpes simplex virus infection and pregnancy
3. 新生児単純ヘルペスウイルス感染：管理および予防 neonatal herpes simplex virus infection management and prevention
4. 性器単純ヘルペスウイルス感染の治療 treatment of genital herpes simplex virus infection
5. 食道の単純ヘルペスウイルス感染 herpes simplex virus infection of the esophagus

English Journal

Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis.

Errami Y, Naura AS, Kim H, Ju J, Suzuki Y, El-Bahrawy AH, Ghonim MA, Hemeida RA, Mansy MS, Zhang J, Xu M, Smulson ME, Brim H, Boulares AH.SourceDepartment of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.
The Journal of biological chemistry.J Biol Chem.2013 Feb 1;288(5):3460-8. doi: 10.1074/jbc.M112.423061. Epub 2012 Dec 10.
Caspase-activated DNase (CAD) is the most favorable candidate for chromatin degradation during apoptosis. Ca(2+)-dependent endonucleases are equally important in internucleosomal DNA fragmentation (INDF), including the PARP-1-regulated DNAS1L3. Despite the elaborate work on these endonucleases, the
PMID 23229555

Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast.

McIsaac RS, Oakes BL, Wang X, Dummit KA, Botstein D, Noyes MB.SourceThe Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA. rmcisaac@princeton.edu
Nucleic acids research.Nucleic Acids Res.2013 Feb 1;41(4):e57. doi: 10.1093/nar/gks1313. Epub 2012 Dec 28.
A general method for the dynamic control of single gene expression in eukaryotes, with no off-target effects, is a long-sought tool for molecular and systems biologists. We engineered two artificial transcription factors (ATFs) that contain Cys(2)His(2) zinc-finger DNA-binding domains of either the
PMID 23275543

Expression of human interferon-α8 synthetic gene under P(BAD) promoter.

Mohammed Y, El-Baky NA, Redwan NA, Redwan EM.SourceAntibody Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, Alexandria, Egypt.
Biochemistry. Biokhimii͡a.Biochemistry (Mosc).2012 Oct;77(10):1210-9. doi: 10.1134/S0006297912100136.
Recombinant human interferon-α8 (rhIFN-α8) was obtained by synthesizing a codon-optimized gene in a two-step polymerase chain reaction (PCR) and expressing it in Escherichia coli. The gene encoding human IFN-α8 shows a high content of rare codons. These were replaced based on E. coli codon usage
PMID 23157301

Japanese Journal

A herpes simplex virus type 1 mutant containing a non-transinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglina