glycodeoxycholic acid

Glycodeoxycholic acid
	IUPAC name 2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid
Identifiers
CAS number	360-65-6
PubChem	3035026
ChEBI	CHEBI:27471
Jmol-3D images	Image 1
	SMILES C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C ;
Properties
Molecular formula	C26H43NO5
Molar mass	449.62 g mol−1
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
	Infobox references

WordNet

street name for lysergic acid diethylamide (同)back breaker, battery-acid, dose, dot, Elvis, loony toons, Lucy in the sky with diamonds, pane, superman, window pane, Zen
any of various water-soluble compounds having a sour taste and capable of turning litmus red and reacting with a base to form a salt
having the characteristics of an acid; "an acid reaction"

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/24 13:44:12」(JST)

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Beneficial and Safety Properties of a Corynebacterium vitaeruminis Strain Isolated from the Cow Rumen.

Colombo M1, Castilho NPA1, Todorov SD1, Nero LA2.
Probiotics and antimicrobial proteins.Probiotics Antimicrob Proteins.2017 Jun;9(2):157-162. doi: 10.1007/s12602-017-9263-0.
PMID 28258546

Environmental Enteric Dysfunction Is Associated With Altered Bile Acid Metabolism.

Semba RD1, Gonzalez-Freire M, Moaddel R, Trehan I, Maleta KM, Khadeer M, Ordiz MI, Ferrucci L, Manary MJ.
Journal of pediatric gastroenterology and nutrition.J Pediatr Gastroenterol Nutr.2017 Apr;64(4):536-540. doi: 10.1097/MPG.0000000000001313.
PMID 27322559

Characterization of the Physicochemical Properties of β-Cyclodextrin-Divinyl Sulfone Polymer Carrier-Bile Acid Systems.

Mohamed MH1, Wang C1, Peru KM2, Headley JV2, Wilson LD1.
Molecular pharmaceutics.Mol Pharm.2017 Mar 29. doi: 10.1021/acs.molpharmaceut.7b00088. [Epub ahead of print]
PMID 28294623

Glycochenodeoxycholic acid promotes proliferation of intestinal epithelia via reduction of cyclic AMP and increase in H2AX phosphorylation after exposure to γ-rays

Ishizuka Satoshi,Shiwaku Maiko,Hagio Masahito,Suzuki Takuya,Hira Tohru,Hara Hiroshi
Biomedical Research 33(3), 159-165, 2012
… In the proliferation assay, significant increases in IEC-6 cell proliferation were observed in response to glycodeoxycholic acid or glycochenodeoxycholic acid (GCDCA). …
NAID 130004470817

Strain Differences in Deconjugation of Bile Acids in Bifidobacterium pseudocatenulatum Isolates

MARIAM Rezaei Sabet,YAP Keng Wai,LIM Long Chang,KHARIDAH Muhammad,SHUHAIMI Mustafa,ABDULLAH Sipat,ALI Abdul Manaf,ATIOAH Abdullah Nur,YAZID Abdul Manap
Bioscience and microflora 23(2), 93-98, 2004-04-01
… Six isolates of bifidobacteria with higher tolerance to 4.0% of bile were further evaluated for their ability to deconjugate different types of bile acids namely taurocholic acid (TC), glycocholic acid (GC), taurochenodeoxycholic acid (TCDC), glycochenodeoxycholic acid (GCDC), taurodeoxycholic acid (TDC), and glycodeoxycholic acid (GDC). …
NAID 10027995027

Measurements of Mutagenic and Antimutagenic Activities of Bile Acids by Rec-assay

Yamada Koji,Lim Ou Beong,Nonaka Michiko,Sugano Michihiro
Bioscience, Biotechnology, and Biochemistry 57(4), 599-602, 1993-04-23
… Cholic, chenodeoxycholic, lithocholic, and glycolithocholic acids exerted much weaker mutagenicity than mitomicin C (MMC), and deoxycholic and glycodeoxycholic acids showed toxicity toward the bacteria. … and their amino acid components (glycine and taurine) were neither toxic nor mutagenic. …
NAID 110002676292