- 関
- complex carbohydrate、conjugated polysaccharide
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/01 08:12:44」(JST)
[Wiki en表示]
Glycoconjugates is the general classification for carbohydrates covalently linked with other chemical species such as proteins, peptides, lipids and saccharides.[1] Glycoconjugates are formed in processes termed glycosylation.
Glycoconjugates are very important compounds in biology and consist of many different categories such as glycoproteins, glycopeptides, peptidoglycans, glycolipids, glycosides and lipopolysaccharides. They are involved in cell–cell interactions, including cell–cell recognition; in cell–matrix interactions; in detoxification processes.
Generally the carbohydrate part(s) play an integral role in the function of a glycoconjugate; prominent examples of this are NCAM and blood proteins where fine details in the carbohydrate structure determine cell binding or not or lifetime in circulation.
Although the important molecular species DNA, RNA, ATP, cAMP, cGMP, NADH, NADPH, and coenzyme A all contain a carbohydrate part generally they are not considered as glycoconjugates.
References
- ^ Glycoconjugates at the US National Library of Medicine Medical Subject Headings (MeSH)
Protein, glycoconjugate: glycoproteins and glycopeptides
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Mucoproteins |
Mucin
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- CD43
- CD164
- MUC1
- MUC2
- MUC3A
- MUC3B
- MUC4
- MUC5AC
- MUC5B
- MUC6
- MUC7
- MUC8
- MUC12
- MUC13
- MUC15
- MUC16
- MUC17
- MUC19
- MUC20
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Other
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- Haptoglobin
- Intrinsic factor
- Orosomucoid
- Peptidoglycan
- Phytohaemagglutinin
- Ovomucin
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Proteoglycans |
CS/DS
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- Decorin
- Biglycan
- Versican
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HS/CS
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CS
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- Chondroitin sulfate proteoglycans: Aggrecan
- Neurocan
- Brevican
- CD44
- CSPG4
- CSPG5
- Platelet factor 4
- Structural maintenance of chromosomes 3
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KS
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- Fibromodulin
- Lumican
- Keratocan
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HS
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Other |
- Activin and inhibin
- ADAM
- Alpha 1-antichymotrypsin
- Apolipoprotein H
- CD70
- Asialoglycoprotein
- Avidin
- B-cell activating factor
- 4-1BB ligand
- Cholesterylester transfer protein
- Clusterin
- Colony-stimulating factor
- Hemopexin
- Lactoferrin
- Membrane glycoproteins
- Myelin protein zero
- Osteonectin
- Protein C
- Protein S
- Serum amyloid P component
- Sialoglycoprotein
- CD43
- Glycophorin
- Glycophorin C
- Thrombopoietin
- Thyroglobulin
- Thyroxine-binding proteins
- Transcortin
- Tumor necrosis factor alpha
- Uteroglobin
- Vitronectin
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Index of inborn errors of metabolism
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Description |
- Metabolism
- Enzymes and pathways: citric acid cycle
- pentose phosphate
- glycoproteins
- glycosaminoglycans
- phospholipid
- cholesterol and steroid
- sphingolipids
- eicosanoids
- amino acid
- urea cycle
- nucleotide
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Disorders |
- Citric acid cycle and electron transport chain
- Glycoprotein
- Proteoglycan
- Fatty-acid
- Phospholipid
- Cholesterol and steroid
- Eicosanoid
- Amino acid
- Purine-pyrimidine
- Heme metabolism
- Symptoms and signs
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Treatment |
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Index of biochemical families
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Carbohydrates |
- Alcohols
- Glycoproteins
- Glycosides
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Lipids |
- Eicosanoids
- Fatty acids
- Glycerides
- Phospholipids
- Sphingolipids
- Steroids
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Nucleic acids |
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Proteins |
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Other |
- Tetrapyrroles
- intermediates
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Glycoconjugates, lipids and glycolipids: sphingolipids and glycosphingolipids, and metabolic intermediates
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Ceramide |
- Cerebroside
- Galactocerebroside
- Glucocerebroside
- Lactosylceramide
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Ganglioside
pathway |
From ganglioside
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From globoside
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From sphingomyelin
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From sulfatide
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To sphingosine
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Other |
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Index of inborn errors of metabolism
|
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Description |
- Metabolism
- Enzymes and pathways: citric acid cycle
- pentose phosphate
- glycoproteins
- glycosaminoglycans
- phospholipid
- cholesterol and steroid
- sphingolipids
- eicosanoids
- amino acid
- urea cycle
- nucleotide
|
|
Disorders |
- Citric acid cycle and electron transport chain
- Glycoprotein
- Proteoglycan
- Fatty-acid
- Phospholipid
- Cholesterol and steroid
- Eicosanoid
- Amino acid
- Purine-pyrimidine
- Heme metabolism
- Symptoms and signs
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Treatment |
|
Index of biochemical families
|
|
Carbohydrates |
- Alcohols
- Glycoproteins
- Glycosides
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Lipids |
- Eicosanoids
- Fatty acids
- Glycerides
- Phospholipids
- Sphingolipids
- Steroids
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Nucleic acids |
|
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Proteins |
|
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Other |
- Tetrapyrroles
- intermediates
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|
UpToDate Contents
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English Journal
- Analysis of porcine granulosa cell death signaling pathways induced by vinclozolin.
- Knet M1, Wartalski K1, Hoja-Lukowicz D2, Tabarowski Z3, Slomczynska M1, Duda M4.
- Theriogenology.Theriogenology.2015 Oct 1;84(6):927-39. doi: 10.1016/j.theriogenology.2015.05.028. Epub 2015 Jun 6.
- Recent studies suggest that disturbing androgen-signaling pathways in porcine ovarian follicles may cause granulosa cell (GC) death. For this reason, we investigated which apoptotic pathway is initiated after GC exposure to an environmental antiandrogen, vinclozolin (Vnz), in vitro. Immunocytochemi
- PMID 26141531
- Synthesis of NAG-thiazoline-derived inhibitors for β-N-acetyl-d-hexosaminidases.
- Kong H1, Chen W2, Lu H3, Yang Q2, Dong Y1, Wang D1, Zhang J4.
- Carbohydrate research.Carbohydr Res.2015 Sep 2;413:135-44. doi: 10.1016/j.carres.2015.06.004. Epub 2015 Jun 16.
- β-N-Acetyl-d-hexosaminidases are responsible for the metabolism of glycoconjugates in diverse physiological processes that are important targets for medicine and pesticide development. Fourteen new NAG-thiazoline derivatives were synthesized by cyclization and click reaction using d-glucosamine hyd
- PMID 26142545
- Erratum to: Visualization and analysis of EPS glycoconjugates of the thermoacidophilic archaeon Sulfolobus metallicus.
- Zhang R1, Neu TR, Zhang Y, Bellenberg S, Kuhlicke U, Li Q, Sand W, Vera M.
- Applied microbiology and biotechnology.Appl Microbiol Biotechnol.2015 Sep;99(17):7357. doi: 10.1007/s00253-015-6859-8.
- PMID 26239073
Japanese Journal
- Mannose-recognition mutant of the galactose/N-acetylgalactosamine-specific C-type lectin CEL-I engineered by site-directed mutagenesis
- Biochimica et Biophysica Acta (BBA) - General Subjects 1850(7), 1457-1465, 2015-07
- NAID 120005611344
- Effects of sesamin on the biosynthesis of chondroitin sulfate proteoglycans in human articular chondrocytes in primary culture
- Peroxisome proliferator-activated receptor alpha mediates enhancement of gene expression of cerebroside sulfotransferase in several murine organs
Related Links
- Welcome to the Glycoconjugate Databank. Glyco-Net Function network of carbohydrates, glycosyltransferases, glycoside hydrolases, its inhibitors, and diseases Structures All carbohydrate structures in The Protein Data Bank This ...
- last update: 2011/10/26 Glycoconjugate Data Bank:Structures The GDB:Structures is a database of glycan structures in the Protein Data Bank. You can upload your PDB file to annotate and check glycan structures in it.
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