English Journal

Influence of ionization source design on matrix effects during LC-ESI-MS/MS analysis.

Ghosh C, Shinde CP, Chakraborty BS.SourceBio-Analytical Department, Cadila Pharmaceuticals Limited, 1389-Trasad Road, Dholka, Gujarat, India. chinmoy ghosh@yahoo.com
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2012 Apr 15;893-894:193-200. Epub 2012 Mar 15.
Glycerophosphocholines (GPChos) are known to cause matrix ionization effects during the analysis of biological samples (i.e. plasma, urine, etc.) in LC-MS/MS. In general, such matrix effect is directly related to an insufficient sample clean-up of the biofluids. In addition to GPCho; design of ioniz
PMID 22464433

Wijeyesekera A, Selman C, Barton RH, Holmes E, Nicholson JK, Withers DJ.SourceBiomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, South Kensington, London SW7 2AZ, United Kingdom.
Journal of proteome research.J Proteome Res.2012 Apr 6;11(4):2224-35. Epub 2012 Feb 27.
Significant advances in understanding aging have been achieved through studying model organisms with extended healthy lifespans. Employing 1H NMR spectroscopy, we characterized the plasma metabolic phenotype (metabotype) of three long-lived murine models: 30% dietary restricted (DR), insulin recepto
PMID 22225495