Nichols BL1, Diaz-Sotomayor M2, Avery SE3, Chacko SK4, Hadsell DL5, Baker SS6, Hamaker BR7, Yan LK8, Lin HM9,10, Quezada-Calvillo R11,12.
Molecular and cellular pediatrics.Mol Cell Pediatr.2016 Dec;3(1):4. doi: 10.1186/s40348-016-0032-z. Epub 2016 Feb 1.
ᅟ: Starch requires six enzymes for digestion to free glucose: two amylases (salivary and pancreatic) and four mucosal maltase activities; sucrase-isomaltase and maltase-glucoamylase. All are deficient in suckling rodents.OBJECTIVE: The objective of this study is to test (13)C-starch digestion befo
In this paper, we investigated the effects of Coptis chinensis polysaccharide (CCP) on hyperglycemia and glucose intolerance in high-fat diet (HFD)-induced diabetic C57BL/6J mice. CCP was prepared by extraction from Coptis chinensis and oral given to the mice. C57BL/6J mice in each of the 5 groups (
Activation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production.
He L1, Chang E2, Peng J2, An H2, McMillin SM3, Radovick S4, Stratakis CA5, Wondisford FE3.
The Journal of biological chemistry.J Biol Chem.2016 May 13;291(20):10562-70. doi: 10.1074/jbc.M116.719666. Epub 2016 Mar 21.
Metformin is the most commonly prescribed oral anti-diabetic agent worldwide. Surprisingly, about 35% of diabetic patients either lack or have a delayed response to metformin treatment, and many patients become less responsive to metformin over time. It remains unknown how metformin resistance or in
… From an energy metabolic point of view, we have analyzed ATP-generation system in the P.furiosus glucogenesis and revealed that a novel regulation site for energy metabolism and a unique mode of ATP regeneration exist in the pathway of P.furiosus. …
glu·co·gen·e·sis (glū'kō-jen'ĕ-sis), Formation of glucose. [gluco- + G. genesis, production] glu·co·gen·e·sis (glōō′kō-jĕn′ĭ-sĭs) n. The formation of glucose through the breakdown of glycogen. glu′co·gen′ic adj. glucogenesis, giving rise to ...