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English Journal

Analyses of chromosome copy number and expression level of four genes in the ciliate Chilodonella uncinata reveal a complex pattern that suggests epigenetic regulation.

Bellec L, Katz LA.SourceDepartment of Biological Sciences, Smith College, Northampton, MA 01063, USA.
Gene.Gene.2012 May 12. [Epub ahead of print]
Chilodonella uncinata, like all ciliates, contains two distinct nuclei in every cell: a germline micronucleus and a somatic macronucleus. The macronucleus develops from the zygotic nucleus through a series of chromosomal rearrangements. Macronuclear development in C. uncinata yields a nucleus with h
PMID 22588027

Evolution of Germline-Limited Sequences in Two Populations of the Ciliate Chilodonella uncinata.

Zufall RA, Sturm M, Mahon BC.SourceDepartment of Biology and Biochemistry, University of Houston, Houston, TX, 77204, USA, rzufall@uh.edu.
Journal of molecular evolution.J Mol Evol.2012 Apr;74(3-4):140-6. Epub 2012 Mar 13.
Ciliates are microbial eukaryotes that separate their nuclear functions into a germline micronucleus and a somatic macronucleus. During development of the macronucleus the genome undergoes a series of reorganization events that includes the precise excision of intervening DNA. Here, we determine the
PMID 22411695