WordNet

the ion NH4 derived from ammonia; behaves in many respects like an alkali metal ion (同)ammonium_ion
a salt or ester of citric acid
cause to form a salt or ester of citric acid
of or relating to or containing iron (同)ferrous

PrepTutorEJDIC

アンモニウム,アンモニア塩基
クエン酸塩
鉄の,鉄を含む

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/07 22:48:32」(JST)

wiki en

Ammonium ferric citrate is a food additive with E number E381 used as an acidity regulator.^{[citation needed]} It is a green or reddish-brown powder which is very soluble in water.

The molecular formula of ammonium iron(III) citrate is variable. It can be prepared by adding Fe(OH)₃ to an aqueous solution of citric acid and ammonia.^[1] The brown form is approximately 9% NH₃, 16.5–18.5% Fe, and 65% hydrated citric acid; the green form is approximately 7.5% NH₃, 14.5–16% Fe, and 75% hydrated citric acid. The green type is more readily reduced by light than the brown.^[2]

Other uses for ammonium ferric citrate include water purification and printing (cyanotype). It is used as a reducing agent of metal salts of low activity like gold and silver and is also in a commonly used recipe with potassium ferricyanide to make cyanotype prints. Ammonium ferric citrate is also used in Kligler iron deeps to determine hydrogen sulfide production in microbial metabolism.

Ammonium ferric citrate is present in Scottish carbonated soft drink Irn-Bru.^[3]

In medicine, ammonium ferric citrate is used as a contrast medium. It is also used as a hematinic.^[2]

Compendial status

Martindale: The Extra Pharmacopoeia ^[4] ^{[clarification needed]}

Notes

^ U.S. Patent 2,644,828
^ ^a ^b Budavari, Susan, ed. (2001), The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (13th ed.), Merck, ISBN 0911910131
^ IRN BRU: our drinks, nutritional information
^ Therapeutic Goods Administration. "Chemical Substances" (PDF). Archived (PDF) from the original on 8 July 2009. Retrieved 27 July 2009.
^ The United States Pharmacopeial Convention. "Revisions to FCC Sixth Edition 2S". Retrieved 27 July 2009.

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 慢性腎疾患における高リン血症の治療 treatment of hyperphosphatemia in chronic kidney disease
2. 治療的血漿交換：合併症 therapeutic plasma exchange complications
3. 遠位（I型）および近位（II型）尿細管性アシドーシスの病因および診断 etiology and diagnosis of distal type 1 and proximal type 2 renal tubular acidosis
4. 大量輸血 massive blood transfusion
5. クエン酸クロミフェンによる排卵誘発 ovulation induction with clomiphene citrate

English Journal

Iron deficiency upregulates Egr1 expression.

Lee SM1, Lee SB, Prywes R, Vulpe CD.
Genes & nutrition.Genes Nutr.2015 Jul;10(4):468. doi: 10.1007/s12263-015-0468-0. Epub 2015 May 19.
Iron-deficient anemia is a prevalent disease among humans. We searched for genes regulated by iron deficiency and its regulated mechanism. cDNA microarrays were performed using Hepa1c1c7 cells treated with 100 μM desferrioxamine (DFO), an iron chelator. Early growth response 1 (Egr1) was upregulat
PMID 25981695

Use of an advanced 3-T MRI movie to investigate articulation.

Nunthayanon K1, Honda E2, Shimazaki K3, Ohmori H4, Inoue-Arai MS5, Kurabayashi T6, Ono T7.
Oral surgery, oral medicine, oral pathology and oral radiology.Oral Surg Oral Med Oral Pathol Oral Radiol.2015 Jun;119(6):684-94. doi: 10.1016/j.oooo.2015.03.003. Epub 2015 Mar 25.
OBJECTIVE: To develop a magnetic resonance imaging (MRI) movie to reveal the dynamic movement of articulators and teeth.STUDY DESIGN: Five healthy females with normal occlusion participated in this study. Various concentrations of MRI contrast media (ferric ammonium citrate [FAC]) were tested for vi
PMID 25956219

Iron diminishes the in vitro biological effect of vanadium.

Ghio AJ1, Stonehuerner J2, Soukup JM2, Dailey LA2, Kesic MJ3, Cohen MD4.
Journal of inorganic biochemistry.J Inorg Biochem.2015 Mar 25. pii: S0162-0134(15)00084-7. doi: 10.1016/j.jinorgbio.2015.03.008. [Epub ahead of print]
Mechanistic pathways underlying inflammatory injury following exposures to vanadium-containing compounds are not defined. We tested the postulate that the in vitro biological effect of vanadium results from its impact on iron homeostasis. Human bronchial epithelial (HBE) cells exposed to vanadyl sul
PMID 25843360

Japanese Journal

Iron facilitator LS081 reduces hypoxia-inducible factor-1α protein and functions as anticancer agent in hepatocellular carcinoma.

田中宏樹,Zhen Li,Katsuya Ikuta,Lynda Addo,Hiroaki Akutsu,Masao Nakamura,Katsunori Sasaki,Takaaki Ohtake,Mikihiro Fujiya,Yoshihiro Torimoto,Jonathan Glass,Yutaka Kohgo
Cancer Science 103(4), 767-774, 2012-04
… In the human hepatocellular carcinoma cell lines Hep3B and HepG2, a combination of LS081 and ferric ammonium citrate (LS081/FeAC) inhibited HIF-1α protein expression but did not inhibit HIF-1α mRNA expression. …
NAID 120004056946

MRI Body Diffusion Weighted Imageにおけるクエン酸鉄アンモニウム水溶液を用いた消化管アーチファクト消去の試み(臨床技術)

高橋俊行,加藤京一,西澤剛,中澤靖夫
日本放射線技術學會雜誌 64(5), 573-578, 2008-05-20
… The purpose of this study was to examine evidence as to whether an oral contrast agent of ferric ammonium citrate could eliminate this artifact from the bowel loop. … We changed the density with ferric ammonium citrate to find the best density. … When a signal of ferric ammonium citrate extended TE time and increased b value, it fell. …
NAID 110006685293

Related Pictures

★リンクテーブル★

リンク元	「クエン酸鉄アンモニウム」
関連記事	「ammonium」「ferric」

「クエン酸鉄アンモニウム」

Ammonium ferric citrate
Names
	IUPAC name 2-Hydroxypropane-1,2,3-tricarboxylate, ammonium iron(3+) salt
	Other names Ferric ammonium citrate; Ammonium Iron(III) Citrate; Ammonium ferric citrate; Iron ammonium citrate; Prothoate+
Identifiers
ATC code	V08CA07
CAS Registry Number	1185-57-5
ChEMBL	ChEMBL1200460
ChemSpider	2338386
EC number	214-686-6
	InChI InChI=1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;/p-2 ; Key: FRHBOQMZUOWXQL-UHFFFAOYSA-L ; InChI=1/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;/p-2; Key: FRHBOQMZUOWXQL-NUQVWONBAA ;
Jmol-3D images	Image
PubChem	3080636
	SMILES [Fe+3].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-].[NH4+] ;
Properties
Chemical formula	C6H5+4yFexNyO7
Molar mass	Variable
Appearance	Reddish-brown powder
Hazards
MSDS	[1]
	Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
	verify (what is: /?)
	Infobox references