WordNet

a thin pliable sheet of material
a pliable sheet of tissue that covers or lines or connects the organs or cells of animals or plants (同)tissue layer

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(生物の)膜,皮膜

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/10 08:50:36」(JST)

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The tunica intima (New Latin "inner coat"), or intima for short, is the innermost tunica (layer) of an artery or vein. It is made up of one layer of endothelial cells and is supported by an internal elastic lamina. The endothelial cells are in direct contact with the blood flow.

The tunicae of blood vessels are three layers — an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica adventitia).

In dissection, the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability, it cannot be separated as a complete membrane. It is a fine, transparent, colorless structure which is highly elastic, and, after death, is commonly corrugated into longitudinal wrinkles.

The inner coat consists of:

A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round or oval nuclei. This endothelium is brought into view most distinctly by staining with silver nitrate.
A subendothelial layer, consisting of delicate connective tissue with branched cells lying in the interspaces of the tissue; in arteries of less than 2 mm in diameter the subendothelial layer consists of a single stratum of stellate cells, and the connective tissue is only largely developed in vessels of a considerable size.
An elastic or fenestrated layer, which consists of a membrane containing a net-work of elastic fibers, having principally a longitudinal direction, and in which, under the microscope, small elongated apertures or perforations may be seen, giving it a fenestrated appearance. It was therefore called by Henle the fenestrated membrane. This membrane forms the chief thickness of the inner coat, and can be separated into several layers, some of which present the appearance of a network of longitudinal elastic fibers, and others a more membranous character, marked by pale lines having a longitudinal direction. In minute arteries the fenestrated membrane is a very thin layer; but in the larger arteries, and especially in the aorta, it has a considerable thickness.

Additional images

Vein
Microphotography of arterial wall with calcified (violet colour) atherosclerotic plaque (haematoxillin and eosin stain)

References

This article incorporates text in the public domain from the 20th edition of Gray's Anatomy (1918)

External links

Histology image: 66_02 at the University of Oklahoma Health Sciences Center - "Aorta"
Anatomy photo: Circulatory/vessels/vessels7/vessels2 - Comparative Organology at University of California, Davis — "Bird, vessels (LM, High)"
Image at About.com

UpToDate Contents

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English Journal

PMID 25731761

Proteomic analysis of the kidney filtration barrier - problems and perspectives.

Rinschen MM1, Benzing T, Limbutara K, Pisitkun T.
Proteomics. Clinical applications.Proteomics Clin Appl.2015 Apr 23. doi: 10.1002/prca.201400201. [Epub ahead of print]
Diseases of the glomerular filter of the kidney are a leading cause of end-stage renal failure. The kidney filter is localized within the renal glomeruli, small microvascular units that are responsible for ultrafiltration of about 180 liters of primary urine every day. The renal filter consists of t
PMID 25907645

Crosstalk in glomerular injury and repair.

Dimke H1, Maezawa Y, Quaggin SE.
Current opinion in nephrology and hypertension.Curr Opin Nephrol Hypertens.2015 Apr 16. [Epub ahead of print]
PURPOSE OF REVIEW: The glomerulus is a unique structure required for filtration of blood, while retaining plasma proteins based on size and charge selectivity. Distinct cell types form the structural unit that creates the filtration barrier. Structurally, fenestrated endothelial cells line the capil
PMID 25887901

Japanese Journal

成長ホルモン治療中に発症したネフローゼ症候群の2例

前川講平,柴野貴之,澤木潤子,高橋千晶,前寛,服部益治,谷澤隆邦
日本小児腎臓病学会雑誌 = Japanese journal of pediatric nephrology 22(1), 35-40, 2009-04-15
　今回，成長ホルモン (GH) 治療中に発症したネフローゼ症候群 (NS) の4歳女児と8歳女児の2例を経験した。それぞれ原疾患はターナー症候群と成長ホルモン分泌不全性低身長であった。2例ともソマトロピンを使用していたが，1例目は投与後2週間で発症し，2例目は投与後3年を経てからであった。ともにNSのステロイド治療への反応性は良好で治療終了後3ヵ月経過しているが再発は認めていない。GH治療中にNS …
NAID 10025170706

Transluminal endoscopic electrosurgical incision of fenestrated duodenal membranes

BLANCO-RODRIGUEZ Gerardo,PENCHYNA-GRUB Jaime,PORRAS-HERNANDEZ Juan D.,TRUJILLO-PONCE Adrian
Pediatric surgery international 24(6), 711-714, 2008-06-01
NAID 10027483336

Related Pictures

★リンクテーブル★

リンク元	「有窓膜」
関連記事	「membrane」

「有窓膜」

Tunica intima
	Transverse section through a small artery and vein of the mucous membrane of the epiglottis of a child. (Tunica intima is at "e")
Details
Latin	Tunica intima
Identifiers
Gray's	p.498
MeSH	A07.231.330.800
Code	TH H3.09.02.0.01003
TA	A12.0.00.018
FMA	55589
	Anatomical terminology