関: felbinac ethyl

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/09/21 12:10:04」(JST)

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Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) of the arylpropionic acid class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.^[1]

Footnotes

^ Kohler C, Tolman E, Wooding W, Ellenbogen L. (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung 30 (4A): 702–707. PMID 6254545.

References

The Merck Index, 12th Edition. 3989
Description of Felbinac on Tiscali [1]

This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

English Journal

A novel protocol for the oral administration of test chemicals to adult zebrafish.

Zang L, Morikane D, Shimada Y, Tanaka T, Nishimura N.SourceDepartment of Translational Medical Science, Graduate School of Medicine, Mie University, Mie 514-8507, Japan. liqing@doc.medic.mie-u.ac.jp
Zebrafish.Zebrafish.2011 Dec;8(4):203-10.
A novel protocol using gluten as a carrier material was developed to administer chemicals to adult zebrafish, per os (p.o.). To evaluate the capacity of gluten to retain chemicals, we prepared gluten granules containing eight types of chemicals with different Log P(ow) values and immersed them in wa
PMID 22181663

Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative.

Ishiguro T, Morishita E, Iohara D, Hirayama F, Wada K, Motoyama K, Arima H, Uekama K.SourceFaculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 860-0082, Japan.
International journal of pharmaceutics.Int J Pharm.2011 Oct 31;419(1-2):161-9. Epub 2011 Aug 5.
2-Hydroxybutyl-β-cyclodextrins (HB-β-CyDs) with different degrees of substitution (D.S.) were prepared and their physicochemical and biological properties and solubilizing abilities were studied and compared with those of 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD). The surface activity of HB-β-C
PMID 21839823

Japanese Journal

A novel protocol for the oral administration of test chemicals to adult zebrafish.

Zang Liqing,Morikane Daizo,Shimada Yasuhito,Tanaka Toshio,Nishimura Norihiro
Zebrafish 8(4), 203-210, 2011-12
… Subsequently, we conducted a pharmacokinetic study of oral administration of felbinac and confirmed that it was successfully delivered into the blood of zebrafish. …
NAID 120005228797

非ステロイド系消炎鎮痛剤の光毒性、光感作能及び持続性光線過敏に対する検討

山崎文和,橋本洋子,堀尾武
日本皮膚科学会雑誌 113(4), 405-411, 2003-04-20
NAID 80015971516

非ステロイド系消炎鎮痛剤の光毒性,光感作能及び持続性光線過敏に対する検討

山﨑文和,橋本洋子,堀尾武
日本皮膚科学会雑誌 = The Japanese journal of dermatology 113(4), 405-411, 2003-04
NAID 40019929496

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Felbinac
Systematic (IUPAC) name
	biphenyl-4-ylacetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	P (UK)
Routes	Topical
Identifiers
CAS number	5728-52-9
ATC code	M02AA08
PubChem	CID 3332
DrugBank	DB07477
ChemSpider	3215
UNII	94WNJ5U8L7
KEGG	D01675
ChEBI	CHEBI:31597
ChEMBL	CHEMBL413965
Chemical data
Formula	C14H12O2
Mol. mass	212.244 g/mol
	SMILES O=C(O)Cc1ccc(cc1)c2ccccc2;
	InChI InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) ; Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N ;
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