フェルビナク
- 関
- felbinac ethyl
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/09/21 12:10:04」(JST)
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Felbinac
|
Systematic (IUPAC) name |
biphenyl-4-ylacetic acid |
Clinical data |
AHFS/Drugs.com |
International Drug Names |
Pregnancy cat. |
? |
Legal status |
P (UK) |
Routes |
Topical |
Identifiers |
CAS number |
5728-52-9 |
ATC code |
M02AA08 |
PubChem |
CID 3332 |
DrugBank |
DB07477 |
ChemSpider |
3215 Y |
UNII |
94WNJ5U8L7 Y |
KEGG |
D01675 Y |
ChEBI |
CHEBI:31597 Y |
ChEMBL |
CHEMBL413965 Y |
Chemical data |
Formula |
C14H12O2 |
Mol. mass |
212.244 g/mol |
SMILES
- O=C(O)Cc1ccc(cc1)c2ccccc2
|
InChI
-
InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) Y
Key:QRZAKQDHEVVFRX-UHFFFAOYSA-N Y
|
Y (what is this?) (verify)
|
Felbinac (INN, or biphenylylacetic acid) is a topical medicine, belonging to the family of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs) of the arylpropionic acid class, which is used to treat muscle inflammation and arthritis. It is an active metabolite of fenbufen.[1]
- ^ Kohler C, Tolman E, Wooding W, Ellenbogen L. (1980). "A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function". Arzneimittelforschung 30 (4A): 702–707. PMID 6254545.
References
- The Merck Index, 12th Edition. 3989
- Description of Felbinac on Tiscali [1]
Topical products for joint and muscular pain (M02)
|
|
Anti-inflammatory preparations,
non-steroids |
Butylpyrazolidines
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- Phenylbutazone
- Mofebutazone
- Clofezone
- Oxyphenbutazone
|
|
Acetic acid derivatives
|
- Tolmetin
- Diclofenac
- Fentiazac
|
|
Other
|
- Benzydamine
- Etofenamate
- Piroxicam
- Felbinac
- Bufexamac
- Ketoprofen
- Bendazac
- Naproxen
- Ibuprofen
- Feprazone
- Niflumic acid
- Meclofenamic acid
- Flurbiprofen
- Suxibuzone
- Indometacin
- Nifenazone
|
|
|
Capsaicin derivatives |
|
|
Other |
- Tolazoline
- Dimethyl sulfoxide
- Idrocilamide
|
|
English Journal
- A novel protocol for the oral administration of test chemicals to adult zebrafish.
- Zang L, Morikane D, Shimada Y, Tanaka T, Nishimura N.SourceDepartment of Translational Medical Science, Graduate School of Medicine, Mie University, Mie 514-8507, Japan. liqing@doc.medic.mie-u.ac.jp
- Zebrafish.Zebrafish.2011 Dec;8(4):203-10.
- A novel protocol using gluten as a carrier material was developed to administer chemicals to adult zebrafish, per os (p.o.). To evaluate the capacity of gluten to retain chemicals, we prepared gluten granules containing eight types of chemicals with different Log P(ow) values and immersed them in wa
- PMID 22181663
- Some pharmaceutical and inclusion properties of 2-hydroxybutyl-β-cyclodextrin derivative.
- Ishiguro T, Morishita E, Iohara D, Hirayama F, Wada K, Motoyama K, Arima H, Uekama K.SourceFaculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto 860-0082, Japan.
- International journal of pharmaceutics.Int J Pharm.2011 Oct 31;419(1-2):161-9. Epub 2011 Aug 5.
- 2-Hydroxybutyl-β-cyclodextrins (HB-β-CyDs) with different degrees of substitution (D.S.) were prepared and their physicochemical and biological properties and solubilizing abilities were studied and compared with those of 2-hydroxypropyl-β-cyclodextrin (HP-β-CyD). The surface activity of HB-β-C
- PMID 21839823
Japanese Journal
- A novel protocol for the oral administration of test chemicals to adult zebrafish.
- Zang Liqing,Morikane Daizo,Shimada Yasuhito,Tanaka Toshio,Nishimura Norihiro
- Zebrafish 8(4), 203-210, 2011-12
- … Subsequently, we conducted a pharmacokinetic study of oral administration of felbinac and confirmed that it was successfully delivered into the blood of zebrafish. …
- NAID 120005228797
- 非ステロイド系消炎鎮痛剤の光毒性、光感作能及び持続性光線過敏に対する検討
- 非ステロイド系消炎鎮痛剤の光毒性,光感作能及び持続性光線過敏に対する検討
- 山﨑 文和,橋本 洋子,堀尾 武
- 日本皮膚科学会雑誌 = The Japanese journal of dermatology 113(4), 405-411, 2003-04
- NAID 40019929496
Related Links
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- Felbinac , Find Complete Details about Felbinac,Felbinac from Supplier or Manufacturer-Dongbang Future Tech & Life Co., Ltd. ... Company Introduction : DONGBANG FTL was established in 1990 on purpose to be admitted as top ...
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参考文献
- http://www.info.pmda.go.jp/go/pack/2649731S1127_1_03/2649731S1127_1_03?view=body
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- 関
- felbinac