fasudil hydrochloride hydrate

• 塩酸ファスジル水和物

関

fasudil、fasudil hydrochloride

WordNet

1. any compound that contains water of crystallization
2. become hydrated and combine with water
3. cause to be hydrated; add water or moisture to; "hydrate your skin"
4. supply water or liquid to in order to maintain a healthy balance; "the bicyclists must be hydrated frequently"
5. small tubular solitary freshwater hydrozoan polyp
6. trouble that cannot be overcome by a single effort because of its many aspects or its persistent and pervasive quality; "we may be facing a hydra that defies any easy solution"
7. a complex consisting of an organic base in association with hydrogen chloride

PrepTutorEJDIC

1. 含水化合物,水化物 / 〈化合物〉‘を'水和させて水化物を作る

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 狭心症の新しい治療法 new therapies for angina pectoris
• 2. 血管攣縮性狭心症 vasospastic angina
• 3. 初期治療に抵抗性を示したレイノー現象の治療 treatment of the raynaud phenomenon resistant to initial therapy
• 4. 肝線維症の新しい治療法 emerging therapies for hepatic fibrosis
• 5. 小児に対する手術室外での鎮静処置に使用する薬剤 pharmacologic agents for pediatric procedural sedation outside of the operating room

English Journal

• Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes.

• Zhou H, Li YJ, Wang M, Zhang LH, Guo BY, Zhao ZS, Meng FL, Deng YG, Wang RY.SourceDepartment of Endocrinology, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
• Acta pharmacologica Sinica.Acta Pharmacol Sin.2011 Aug;32(8):999-1008. doi: 10.1038/aps.2011.54. Epub 2011 Jul 11.
• AIM: To investigate whether activation of RhoA/Rho kinase (ROCK) is involved in myocardial fibrosis in diabetic hearts.METHODS: A rat model of type 2 diabetes was established using high fat diet combined with streptozotocin (30 mg/kg, ip). Animals were randomly divided into 3 groups: control rats, u
• PMID 21743486

• Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways.

• Wang N, Guan P, Zhang JP, Li YQ, Chang YZ, Shi ZH, Wang FY, Chu L.SourceDepartment of Pharmacology, School of Basic Medicine, Heibei Medical University, Shijiazhuang 050091, Hebei, China.
• Journal of cellular biochemistry.J Cell Biochem.2011 Jul;112(7):1920-9. doi: 10.1002/jcb.23112.
• The Rho-kinase (ROCK) plays an important role in the pathogenesis of heart injury. Recent cellular and molecular biology studies indicated a pivotal role of the RhoA/ROCK cascade in many aspects of cardiovascular function such as heart failure, cardiac hypertrophy, and ventricular remodeling followi
• PMID 21433064

Japanese Journal

• Fasudil hydrochloride hydrate, a Rho-kinase (ROCK) inhibitor, suppresses collagen production and enhances collagenase activity in hepatic stellate cells

• FUKUSHIMA M
• Liver Int 25, 829-838, 2005
• NAID 30007282744

Related Links

• fasudil hydrochloride hydrate (AT-877) - Product Profile ...

Comprehensive at-877 portfolio, including molecular targets, MOA, partnerships, milestones. Pipeline & competitive intelligence. Clinical & deal history. Market drivers & investment opportunities. ... Company Asahi Kasei Pharma ...

• Fasudil hydrochloride hydrate, a Rho-kinase inhibitor ...

1. J Cell Biochem. 2011 Jul;112(7):1920-9. doi: 10.1002/jcb.23112. Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, suppresses isoproterenol-induced heart failure in rats via JNK and ERK1/2 pathways. Wang N, Guan P, Zhang ...

---

★リンクテーブル★

リンク元	「ファスジル」「fasudil hydrochloride」「塩酸ファスジル水和物」
関連記事	「hydrate」「fasudil」「fasudil hydrochloride」「hydrochloride」「hydra」

「ファスジル」

　　[★]

英

fasudil

化

塩酸ファスジル水和物 fasudil hydrochloride hydrate、塩酸ファスジル fasudil hydrochloride

商

エリル

• 脳動脈瘤破裂後の脳血管攣縮の予防や脳虚血改善のために用いられる。

「fasudil hydrochloride」

　　[★]

• 塩酸ファスジル

関

fasudil、fasudil hydrochloride hydrate

「塩酸ファスジル水和物」

　　[★]

英

fasudil hydrochloride hydrate

関

ファスジル

「hydrate」

　　[★]

• n.

• 水和物

• v.

• 水和させる、水分補給する

関

hydration、water supply

　 　 　 　 　

「fasudil」

　　[★]

ファスジル

関

fasudil hydrochloride、fasudil hydrochloride hydrate

「fasudil hydrochloride」

　　[★]

• 塩酸ファスジル

関

fasudil、fasudil hydrochloride hydrate

「hydrochloride」

　　[★] 塩酸塩、ハイドロクロライド 　

「hydra」

　　[★]

ヒドラ

関

Hydra