WordNet

to conduct a test or investigation; "We are experimenting with the new drug in order to fight this disease"
the act of conducting a controlled test or investigation (同)experimentation
a venture at something new or different; "as an experiment he decided to grow a beard"
the testing of an idea; "it was an experiment in living"; "not all experimentation is done in laboratories" (同)experimentation
try something new, as in order to gain experience; "Students experiment sexually"; "The composer experimented with a new style" (同)try out
relating to or based on experiment; "experimental physics"
relying on observation or experiment; "experimental results that supported the hypothesis" (同)data-based, observational
of the nature of or undergoing an experiment; "an experimental drug"
a usually malignant tumor arising from connective tissue (bone or muscle etc.); one of the four major types of cancer

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1. エイズ関連カポジ肉腫：病期分類および治療 aids related kaposi sarcoma staging and treatment
2. 放射線関連肉腫 radiation associated sarcomas
3. 乳房肉腫：治療 breast sarcoma treatment
4. 転移性軟部組織肉腫の全身治療 systemic treatment of metastatic soft tissue sarcoma
5. 子宮肉腫：分類、臨床症状、および診断 uterine sarcoma classification clinical manifestations and diagnosis

Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.

Kovar H.
Expert opinion on therapeutic targets.Expert Opin Ther Targets.2014 Nov;18(11):1315-28. doi: 10.1517/14728222.2014.947963. Epub 2014 Aug 27.
INTRODUCTION: Ewing sarcoma (ES) represents the paradigm of an aberrant E-twenty-six (ETS) oncogene-driven cancer. It is characterized by specific rearrangements of one of five alternative ETS family member genes with EWSR1. There is experimental evidence that the resulting fusion proteins act as ab
PMID 25162919

Tumor genotype is an independent prognostic factor in primary gastrointestinal stromal tumors of gastric origin: A European multicenter analysis based on ConticaGIST.

Wozniak A1, Rutkowski P2, Schöffski P3, Ray-Coquard I4, Hostein I5, Schildhaus HU6, Le Cesne A7, Bylina E8, Limon J9, Blay JY10, Siedlecki JA11, Wardelmann E12, Sciot R13, Coindre JM14, Debiec-Rychter M15.
Clinical cancer research : an official journal of the American Association for Cancer Research.Clin Cancer Res.2014 Oct 7. pii: clincanres.1677.2014. [Epub ahead of print]
Purpose: While the mutational status in gastrointestinal stromal tumors (GIST) can predict the response to treatment with tyrosine kinase inhibitors, the role of tumor genotype as a prognostic factor remains controversial. The ConticaGIST study sought to determine the pathologic and molecular factor
PMID 25294914

Suppression of deacetylase SIRT1 mediates tumor suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcoma.

Ban J1, Aryee DN1, Fourtouna A1, van der Ent W2, Kauer M1, Niedan S1, Machado I3, Rodriguez-Galindo C4, Tirado OM5, Schwentner R1, Picci P6, Flanagan AM7, Berg V1, Strauss SJ8, Scotlandi K9, Lawlor ER10, Snaar-Jagalska E11, Llombart-Bosch A12, Kovar H13.
Cancer research.Cancer Res.2014 Oct 3. pii: canres.1736.2014. [Epub ahead of print]
The developmental receptor NOTCH plays an important role in various human cancers as a consequence of oncogenic mutations. Here we describe a novel mechanism of NOTCH-induced tumor suppression involving modulation of the deacetylase SIRT1, providing a rationale for the use of SIRT1 inhibitors to tre
PMID 25281719