English Journal

Gentry J, Price DJ, Peiris AN.
Southern medical journal.South Med J.2013 Sep;106(9):492. doi: 10.1097/SMJ.0b013e3182a5ee77.
PMID 24002551

Apocynin and raisanberine alleviate intermittent hypoxia induced abnormal StAR and 3β-HSD and low testosterone by suppressing endoplasmic reticulum stress and activated p66Shc in rat testes.

Zhang GL, Dai DZ, Zhang C, Dai Y.SourceCollege of Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Reproductive toxicology (Elmsford, N.Y.).Reprod Toxicol.2013 Apr;36:60-70. doi: 10.1016/j.reprotox.2012.12.002. Epub 2012 Dec 25.
We hypothesized that hypoxia induced testicular damage is mediated by an activated NADPH oxidase (NOX), therefore, APO (apocynin) an inhibitor of NOX and raisanberine (RS), a calcium influx inhibitor were tested if they could attenuate hypoxic toxicity to the testis. Male Sprague-Dawley rats were ex
PMID 23270704

Juvenile parkinsonism, hypogonadism and Leigh-like MRI changes in a patient with m.4296G>A mutation in mitochondrial DNA.

Martikainen MH, Kytövuori L, Majamaa K.SourceUniversity of Turku and Turku University Hospital, Division of Clinical Neurosciences, Turku, Finland.
Mitochondrion.Mitochondrion.2013 Mar;13(2):83-6. doi: 10.1016/j.mito.2013.01.012. Epub 2013 Feb 7.
Leigh syndrome is a mitochondrial disease with considerable clinical and genetic variation. We present a 16-year-old boy with Leigh-like syndrome and broad developmental retardation, parkinsonism and hypogonadism. Sequencing of the entire mitochondrial DNA from blood revealed the m.4296G>A mutati
PMID 23395828