erythrodermic

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Clinical experience with systemic cyclosporine A treatment in severe childhood psoriasis.

Bulbul Baskan E1, Yazici S1, Tunali S1, Saricaoglu H1.
The Journal of dermatological treatment.J Dermatolog Treat.2015 Dec 10:1-4. [Epub ahead of print]
BACKGROUND: Severe forms of psoriasis including erythrodermic or pustular psoriasis, which require a more aggressive therapeutic approach such as phototherapy or systemic therapies, are rarely seen. Systemic toxicity and long-term safety of these agents are serious concerns in children.OBJECTIVE: We
PMID 26651208

[Profuse sarcoidosis associated with multiple cutaneous squamous cell carcinomas].

Ouahidi FE1, Hocar O2, Akhdari N2, Hazmiri FZ3, Fakhri A3, Belaabidia B3, Benchemkha Y4, Ettabli S4, Fadili O5, Louad I5, Amal S2.
Annales de dermatologie et de vénéréologie.Ann Dermatol Venereol.2015 Dec;142(12):751-6. doi: 10.1016/j.annder.2015.08.012. Epub 2015 Oct 24.
BACKGROUND: The cutaneous signs of sarcoidosis are polymorphous and occasionally misleading. Herein, we report a rare case of profuse sarcoidosis involving various rare cutaneous signs specific to the disease associated with multiple cutaneous squamous cell carcinomas.PATIENTS AND METHODS: A seventy
PMID 26602445

Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris.

Berki DM1, Liu L2, Choon SE3, David Burden A4, Griffiths CE5, Navarini AA6, Tan ES7, Irvine AD8,9, Ranki A10, Ogo T11, Petrof G2, Mahil SK1, Duckworth M2, Allen MH2, Vito P12, Trembath RC13, McGrath J2, Smith CH2, Capon F1, Barker JN2.
The Journal of investigative dermatology.J Invest Dermatol.2015 Dec;135(12):2964-70. doi: 10.1038/jid.2015.288. Epub 2015 Jul 23.
Caspase recruitment family member 14 (CARD14, also known as CARMA2), is a scaffold protein that mediates NF-κB signal transduction in skin keratinocytes. Gain-of-function CARD14 mutations have been documented in familial forms of psoriasis vulgaris (PV) and pityriasis rubra pilaris (PRP). More rece
PMID 26203641