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English Journal

Structural studies of virus-antibody immune complexes (poliovirus type I): Characterization of the epitopes in 3D.

Bannwarth L1, Girerd-Chambaz Y2, Arteni AA1, Guigner JM1, Lemains J1, Ronzon F2, Manin C2, Vénien-Bryan C3.
Molecular immunology.Mol Immunol.2015 Feb;63(2):279-86. doi: 10.1016/j.molimm.2014.07.014. Epub 2014 Aug 19.
The inactivated polio vaccine (IPV) contains poliovirus (PVs) samples that belong to serotypes 1, 2 and 3. All three serotypes contain the D-antigen, which induces protective antibodies. The antigenic structure of PVs consists of at least four different antigenic sites and the D-antigen content repr
PMID 25146483

Carrier priming with CRM197 or diphtheria toxoid has a different impact on the immunogenicity of the respective glycoconjugates: Biophysical and immunochemical interpretation.

Pecetta S1, Lo Surdo P1, Tontini M1, Proietti D1, Zambonelli C1, Bottomley MJ1, Biagini M1, Berti F1, Costantino P1, Romano MR2; Study Group.
Vaccine.Vaccine.2015 Jan 3;33(2):314-20. doi: 10.1016/j.vaccine.2014.11.026. Epub 2014 Nov 22.
Glycoconjugate vaccines play an enormous role in preventing infectious diseases. The main carrier proteins used in commercial conjugate vaccines are the non-toxic mutant of diphtheria toxin (CRM197), diphtheria toxoid (DT) and tetanus toxoid (TT). Modern childhood routine vaccination schedules inclu
PMID 25448110

In silico analysis of Acinetobacter baumannii phospholipase D as a subunit vaccine candidate.

Hosseingholi EZ1, Rasooli I, Gargari SL.
Acta biotheoretica.Acta Biotheor.2014 Dec;62(4):455-78. doi: 10.1007/s10441-014-9226-8. Epub 2014 Jun 24.
The rate of human health care-associated infections caused by Acinetobacter baumannii has increased significantly in recent years for its remarkable resistance to desiccation and most antibiotics. Phospholipases, capable of destroying a phospholipid substrate, are heterologous group of enzymes which
PMID 24957752

Hoshino Tomonori,Kondo Yoshio,Saito Kan,Terao Yutaka,Okahashi Nobuo,Kawabata Shigetada,Fujiwara Taku
Clinical and Vaccine Immunology : CVI 18(9), 1552-1561, 2011-09
In the development of a component vaccine against caries, the catalytic region (CAT) and glucan-binding domain (GBD) of glucosyltransferase B (GtfB) from Streptococcus mutans have been employed as tar …
NAID 120003751840

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Archives of Histology and Cytology 72(4/5), 217-225, 2009
… We finally succeeded in mapping the epitopic region within the α Actinin-4 molecule. …
NAID 130004462736

Activation and control of pathogenic T cells in OSP/claudin-11-induced EAE in SJL/J mice are dominated by their focused recognition of a single epitopic residue (OSP58M)