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1. Pathophysiology of plaque psoriasispathophysiology of plaque psoriasis [show details]
…(including TNF-alpha and iNOS-expressing dendritic cells [TIP-DCs], 6-sulfo LacNAc dendritic cells [slanDCs], and epidermal dendritic cells [eDCs]) recruited in response to the release of IFN-alpha and other …
2. 濾胞樹状細胞肉腫follicular dendritic cell sarcoma [show details]
…monocyte/macrophage and dendritic cell phenotypes. They include entities that are malignant (histiocytic sarcomas, interdigitating dendritic cell sarcoma, follicular dendritic cell sarcoma [FDCS],… nearly all cases of FDCS overexpress epidermal growth factor receptor (EGFR),…
3. 自然免疫系の概要an overview of the innate immune system [show details]
…adaptive immune system. Dendritic cells capture, process, and present antigens to T cells in order to induce adaptive immunity or tolerance to self-antigens. The functions of dendritic cells and other antigen-presenting …
4. 芽球性形質細胞様樹状細胞腫瘍blastic plasmacytoid dendritic cell neoplasm [show details]
…confirmation that BPDCN is derived from plasmacytoid dendritic cells (type 2 dendritic cells), the current nomenclature, blastic plasmacytoid dendritic cell neoplasm, was chosen to describe the entity in the …
5. アレルギー性接触皮膚炎の基本的機序および病態生理basic mechanisms and pathophysiology of allergic contact dermatitis [show details]
…converted to protein-reactive species via oxidation or metabolic transformation by epidermal keratinocytes and/or dendritic cells . Additional factors influencing the sensitizing ability of haptens include lipophilicity …

English Journal

Pigmented Facial Contact Dermatitis to Benzyl Salicylate: A Comparative Histopathological and Immunohistochemical Study of the Involved Skin and the Positive Patch Test Site.

Zaaroura H, Bergman R, Nevet MJ.
The American Journal of dermatopathology. 2019 Jun;41(6)443-447.
Pigmented contact dermatitis (PCD) is a noneczematous variant of allergic contact dermatitis, and benzyl salicylate is one of its causes. This type of PCD shows nonlichenoid interface dermatitis with pigment incontinence. We aimed to characterize the earliest histopathological changes of this reacti
PMID 30211732

Impact of apolipoprotein A1- or lecithin:cholesterol acyltransferase-deficiency on white adipose tissue metabolic activity and glucose homeostasis in mice.

Xepapadaki E, Maulucci G, Constantinou C, Karavia EA, Zvintzou E, Daniel B, Sasson S, Kypreos KE.
Biochimica et biophysica acta. Molecular basis of disease. 2019 Jun;1865(6)1351-1360.
High density lipoprotein (HDL) has attracted the attention of biomedical community due to its well-documented role in atheroprotection. HDL has also been recently implicated in the regulation of islets of Langerhans secretory function and in the etiology of peripheral insulin sensitivity. Indeed, da
PMID 30742993

Redefining the signaling pathways from pluripotency to pancreas development: In vitro β-cell differentiation.

Hashemitabar M, Heidari E.
Journal of cellular physiology. 2019 Jun;234(6)7811-7827.
Pancreatic β-cells are destroyed by the immune system, in type 1 diabetes (T1D) and are impaired by glucose insensitivity in type 2 diabetes (T2D). Islet-cells transplantation is a promising therapeutic approach based on in vitro differentiation of pluripotent stem cells (PSCs) to insulin-producing
PMID 30480819

Japanese Journal

Resolvin E1 attenuates murine psoriatic dermatitis

Sawada Yu,Honda Tetsuya,Nakamizo Satoshi,Otsuka Atsushi,Ogawa Narihito,Kobayashi Yuichi,Nakamura Motonobu,Kabashima Kenji
Scientific Reports (8), 2018-12
… RvE1 potently suppressed the inflammatory cell infiltration and epidermal hyperplasia in the psoriatic skin. … Consistently, RvE1 inhibited IL-23 production by dendritic cells (DCs) in vitro. … Furthermore, RvE1 exerted inhibitory effects on migration of cutaneous DCs and γδ T cells, a major IL-17-producing cell population in mouse, both in vivo and in vitro. …
NAID 120006539571

Preventive effect of Dioscorea japonica on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E2 synthetic pathway

Tsukayama Izumi,Miki Yoshimi,Murakami Makoto,Suzuki-Yamamoto Toshiko,Toda Keisuke,Takeda Yasunori,Mega Takuto,Tanaka Mitsuki,Kawakami Yuki,Takahashi Yoshitaka,Kimoto Masumi,Yamamoto Kei
Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　ａｎｄ　Ｎｕｔｒｉｔｉｏｎ 62(2), 139-147, 2018
… on squamous cell carcinoma of mouse skin. … extract topical application suppressed the expression of cyclooxygenase-2, microsomal prostaglandin E synthase-1, interleukin-1β and interleukin-6 and inhibited tumor formation, hyperplasia and inflammatory cell infiltration. …
NAID 130006407477

Effect of administrating polysaccharide from black currant (Ribes nigrum L.) on atopic dermatitis in NC/Nga mice

ASHIGAI Hiroshi,KOMANO Yuta,WANG Guanying,KAWACHI Yasuji,SUNAGA Kazuko,YAMAMOTO Reiko,TAKATA Ryoji,MIYAKE Mika,YANAI Takaaki
Bioscience of Microbiota, Food and Health 37(1), 19-24, 2018
… It induces IFN-γ production from myeloid dendritic cells. … Finally, we confirmed that CAPS administration suppresses mast cell migration to epidermal skin. …
NAID 130006321444