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English Journal

Alcohol odor elicits appetitive facial expressions in human neonates prenatally exposed to the drug.

Faas AE1, March SM2, Moya PR3, Molina JC4.
Physiology & behavior.Physiol Behav.2015 Sep 1;148:78-86. doi: 10.1016/j.physbeh.2015.02.031. Epub 2015 Feb 21.
Specific memories arise during prenatal life as a function of fetal processing of chemosensory stimuli present in the amniotic fluid. Preclinical studies indicate that fetal exposure to alcohol modifies subsequent neonatal and infantile responsiveness towards the sensory attributes of the drug. It h
PMID 25707382

Systemic vasculitis and pregnancy: A multicenter study on maternal and neonatal outcome of 65 prospectively followed pregnancies.

Fredi M1, Lazzaroni MG1, Tani C2, Ramoni V3, Gerosa M4, Inverardi F3, Sfriso P5, Caramaschi P6, Andreoli L1, Sinico RA7, Motta M1, Lojacono A1, Trespidi L8, Strigini F2, Brucato A9, Caporali R3, Doria A5, Guillevin L10, Meroni PL4, Montecucco C3, Mosca M2, Tincani A11.
Autoimmunity reviews.Autoimmun Rev.2015 Aug;14(8):686-691. doi: 10.1016/j.autrev.2015.03.009. Epub 2015 Apr 7.
OBJECTIVE: Systemic vasculitis (SV) are uncommon diseases that rarely affect women during their reproductive age; little data, mainly retrospective, is available on this topic. The aim of our study was to evaluate maternal/neonatal outcome and disease course before, during and after pregnancy.METHOD
PMID 25858351

Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal gestational glucose level.

Xie X1, Gao H1, Zeng W2, Chen S2, Feng L2, Deng D2, Qiao FY2, Liao L1, McCormick K3, Ning Q4, Luo X1.
Clinical science (London, England : 1979).Clin Sci (Lond).2015 Aug 1;129(4):385-94. doi: 10.1042/CS20140688.
Intrauterine exposure to hyperglycaemia may increase the risk of later-life metabolic disorders. Although the underlying mechanism is not fully understood, epigenetic dysregulation in fetal programming has been implicated. With regard to energy homoeostasis, PGC-1α (peroxisome-proliferator-activate
PMID 25875376

半田宏,伊藤拓水,安藤秀樹
Organ Biology 21(2), 134-140, 2014
Half a century ago, the sedative thalidomide caused one of the worst notorious drug disasters in history, with more than 10,000 babies born with deformities. The drug is now used in the treatment of m …
NAID 130004715794

栢森良二
The Japanese Journal of Rehabilitation Medicine 50(12), 957-961, 2013
… Thalidomide embryopathy resulted in babies born with deformities such as phocomelia after their mothers took only a few tablets of thalidomide drug during 36 to 56 days after their last menstrual periods. … There are two thalidomide embryopathy groups depending upon whether their hypoplasia is in the limbs or the auditory organs. …
NAID 130003393543