WordNet

capable of resuming original shape after stretching or compression; springy; "an elastic band"; "a youthful and elastic walk"
a fabric made of yarns containing an elastic material
able to adjust readily to different conditions; "an adaptable person"; "a flexible personality"; "an elastic clause in a contract" (同)flexible, pliable, pliant
tell a relatively insignificant lie; "Fibbing is not acceptable, even if you dont call it lying"
a trivial lie; "he told a fib about eating his spinach"; "how can I stop my child from telling stories?" (同)story, tale, tarradiddle, taradiddle
a slender and greatly elongated substance capable of being spun into yarn (同)fibre
a leatherlike material made by compressing layers of paper or cloth (同)fibre, vulcanized fiber
any of several elongated, threadlike cells (especially a muscle fiber or a nerve fiber) (同)fibre

PrepTutorEJDIC

『弾力のある』,伸縮自在の / 融通性のある / ゴムひも;ゴムひもで作った物,靴下留め,ズボンつり
(ささいな,罪のない)うそ / 軽いうそをつく

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/30 20:06:59」(JST)

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Elastic fibers (or yellow fibers) are bundles of proteins (elastin) found in extracellular matrix^[1] of connective tissue and produced by fibroblasts and smooth muscle cells in arteries. These fibers can stretch up to 1.5 times their length, and snap back to their original length when relaxed. Elastic fibers include elastin, elaunin and oxytalan.

Elastic tissue is classified as "connective tissue proper".^[2]

The elastic fiber is formed from the elastic microfibril (consisting of numerous proteins such as microfibrillar-associated glycoproteins, fibrillin, fibullin, and the elastin receptor) and amorphous elastin.

The microfibril scaffolds and organizes the deposition of amorphous elastin. Amorphous elastin forms from monomers of soluble tropoelastin which is insolubilized and crosslinked into amorphous elastin by lysyl oxidase. Lysyl oxidase reacts with specific lysine residues and by oxidative deamination generates reactive aldehydes and allysine.

These reactive aldehydes and allysines can react with lysine and other allysine residues to crosslink and form desmosine, isodesmosine, and a number of other polyfunctional crosslinks that join surrounding elastin molecules to build an elastin matrix and elastic fiber. These unique crosslinks are responsible for elastin's elasticity.

Distribution

Elastic fibers are found in the skin, lungs, arteries, veins, connective tissue proper, elastic cartilage, periodontal ligament, fetal tissue and other structures.

Histology

Elastic fibers stain well with aldehyde fuchsin, orcein,^[3] and Weigert's elastic stain in histological sections.

The permanganate-bisulfite-toluidine blue reaction is a highly selective and sensitive method for demonstrating elastic fibers under polarizing optics. The induced birefringence demonstrates the highly ordered molecular structure of the elastin molecules in the elastic fiber. This is not readily apparent under normal optics.

Defects and disease

There is evidence to believe that certain defects of any components of the elastic matrix may impair and alter the structural appearance of elastic and collagen fibers.

Cutis laxa and Williams syndrome have elastic matrix defects that have been directly associated with alterations in the elastin gene.

Alpha-1 antitrypsin deficiency is a genetic disorder where elastin is excessively degraded by elastase, a degrading protein released by neutrophils during the inflammatory response. This leads most often to emphysema and liver disease in affected individuals.

Buschke-Ollendorff syndrome, Menkes disease, pseudoxanthoma elasticum, and Marfan's syndrome have been associated with defects in copper metabolism and lysyl oxidase or defects in the microfibril (defects in fibrillin, or fibullin for example).

Hurler disease, a lysosomal storage disease, is associated with an altered elastic matrix.

Hypertension and some congenital heart defects are associated with alterations in the great arteries, arteries, and arterioles with alterations in the elastic matrix.

References

^ Liu X, Zhao Y, Gao J et al. (February 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. 36 (2): 178–82. doi:10.1038/ng1297. PMID 14745449.
^ Strum, Judy M.; Gartner, Leslie P.; Hiatt, James L. (2007). Cell biology and histology. Hagerstwon, MD: Lippincott Williams & Wilkins. p. 83. ISBN 0-7817-8577-4.
^ "Connective Tissue".

External links

Histology image: 00801ooa – Histology Learning System at Boston University - "Connective Tissue elastic fibers "
UIUC Histology Subject 328
Anatomy photo: TermsCells&Tissues/connective/elastic/elastic2 - Comparative Organology at University of California, Davis - "Connective tissue, elastic (LM, High)"

UpToDate Contents

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1. マハイム束の頻拍 mahaim fiber tachycardias
2. 下肢慢性静脈疾患の内科的管理 medical management of lower extremity chronic venous disease
3. 換気調節 control of ventilation
4. 胸部大動脈瘤の臨床的特徴および診断 clinical features and diagnosis of thoracic aortic aneurysm
5. 正常な加齢 normal aging

English Journal

An annulus fibrosus closure device based on a biodegradable shape-memory polymer network.

Sharifi S, van Kooten TG, Kranenburg HJ, Meij BP, Behl M, Lendlein A, Grijpma DW.SourceUniversity of Groningen, University Medical Center Groningen, Department of Biomedical Engineering, W.J. Kolff Institute, PO Box 196, 9700 AD Groningen, The Netherlands.
Biomaterials.Biomaterials.2013 Nov;34(33):8105-13. doi: 10.1016/j.biomaterials.2013.07.061. Epub 2013 Aug 6.
Injuries to the intervertebral disc caused by degeneration or trauma often lead to tearing of the annulus fibrosus (AF) and extrusion of the nucleus pulposus (NP). This can compress nerves and cause lower back pain. In this study, the characteristics of poly(d,l-lactide-co-trimethylene carbonate) ne
PMID 23932501

The design trend in tissue-engineering scaffolds based on nanomechanical properties of individual electrospun nanofibers.

Janković B, Pelipenko J, Skarabot M, Muševič I, Kristl J.SourceUniversity of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia. Electronic address: biljana.jankovic@ffa.uni-lj.si.
International journal of pharmaceutics.Int J Pharm.2013 Oct 15;455(1-2):338-47. doi: 10.1016/j.ijpharm.2013.06.083. Epub 2013 Jul 29.
This paper especially highlights the finding that the mechanical properties of polymeric nanofibers can be tuned by changing the fiber size as well as the composition. For this purpose, the bending Young's modulus was determined using atomic force microscope by involving single-material (polyvinyl a
PMID 23906751

Poly(N-isopropylacrylamide) hydrogels with interpenetrating multiwalled carbon nanotubes for cell sheet engineering.

Chen YS, Tsou PC, Lo JM, Tsai HC, Wang YZ, Hsiue GH.SourceDepartment of Chemical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan, ROC.
Biomaterials.Biomaterials.2013 Oct;34(30):7328-34. doi: 10.1016/j.biomaterials.2013.06.017. Epub 2013 Jul 1.
Hydrogels have been developed as artificial extracellular matrixes (ECMs) to mimic native tissue microenvironments for various applications. Unfortunately, poly(N-isopropylacrylamide) (PNIPAAM)-based hydrogels are not suitable for cell culturing and cell sheet preparation. Carbon nanotubes (CNTs), w
PMID 23827188

Japanese Journal

天然繊維撚糸およびこれを用いたグリーンコンポジットの力学特性に及ぼす撚糸構造の影響 (特集信頼性工学)

吉田一幾,黒瀬司,中村理恵 [他]
材料 61(2), 111-118, 2012-02
NAID 40019203165

連続走行紙における剪断ジワ発生要因の解析

小林孝男
紙パ技協誌 65(9), 928-943, 2011-09-01
NAID 10029494626

Related Pictures

★リンクテーブル★

リンク元	「弾性線維」「elastic tissue」
関連記事	「elastic」

「弾性線維」

Elastic fiber
	Subcutaneous tissue from a young rabbit. Highly magnified. (Elastic fibers labeled at right. )
Identifiers
Gray's	p.377
Dorlands; /Elsevier	f_05/12360925
	Anatomical terminology