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English Journal

Efficacy and Safety of Ecabet Sodium as an Adjuvant Therapy for Helicobacter pylori Eradication: A Systematic Review and Meta-Analysis.

Wang Y1, Wang B, Lv ZF, Yang Y, Wang F, Wang H, Chen S, Xie Y, Zhou X.
Helicobacter.Helicobacter.2014 Oct;19(5):372-81. doi: 10.1111/hel.12136. Epub 2014 May 14.
BACKGROUND: Several studies have reported that the application of ecabet sodium during the eradication of Helicobacter pylori can improve the eradication rate and reduce therapy-associated side effects. However, the efficacy and safety of this therapy are controversial.OBJECTIVES: To determine wheth
PMID 24826809

Efficacy of gastro-retentive forms of ecabet sodium in the treatment of gastric ulcer in rats.

Kim JY1, Bae HJ, Choi J, Lim JR, Kim SW, Lee SH, Park ES.
Archives of pharmacal research.Arch Pharm Res.2014 Aug;37(8):1053-62. doi: 10.1007/s12272-013-0278-0. Epub 2013 Nov 20.
The purpose of the present study is to investigate the influence of gastric retention of ecabet sodium (ECS) on its mucoprotective effect in rat ulcer models. Mini-tablets containing 9 mg ECS were prepared using the direct compression method. The release rates of ECS mini-tablets were controlled by
PMID 24254934

Curcumin and anthocyanin inhibit pepsin-mediated cell damage and carcinogenic changes in airway epithelial cells.

Samuels TL1, Pearson AC, Wells CW, Stoner GD, Johnston N.
The Annals of otology, rhinology, and laryngology.Ann Otol Rhinol Laryngol.2013 Oct;122(10):632-41.
OBJECTIVES: Laryngopharyngeal reflux (LPR) is associated with inflammatory and neoplastic airway diseases. Gastric pepsin internalized by airway epithelial cells during reflux contributes to oxidative stress, inflammation, and carcinogenesis. Several plant extracts and compounds inhibit digestive en
PMID 24294686

Triple Therapy with Ecabet Sodium, Amoxicillin and Lansoprazole for 2 Weeks as the Rescue Regimen for H. pylori Infection

Furuta Takahisa,Kato Mototsugu,Sugimoto Mitsushige,Sasaki Makoto,Kamoshida Toshiro,Furukawa Kouichi,Inaba Tomoki,Tomita Takashige,Shirai Takayuki,Ishii Naoki,Nomura Hideyuki,Konda Yoshitaka,Asaka Masahiro, the JAPAN GAST STUDY GROUP
Internal Medicine 50(5), 369-374, 2011
… Background/Aim Ecabet sodium has an anti-H. … We assessed the efficacy of ecabet sodium in the rescue therapy for the eradication of H. … LAC2E, lansoprazole 30 mg bid + amoxicillin 750 mg bid + clarithromycin 200 mg bid + ecabet sodium 2 g bid for 1 week; … and LA2E, lansoprazole 30 mg bid + amoxicillin 750 mg bid + ecabet sodium 2 g bid for 2 weeks. …
NAID 130000649845

Ecabet sodium induces neuronal nitric oxide synthase-derived nitric oxide synthesis and gastric adaptive relaxation in the human stomach

MATSUMOTO Yoshiaki,ITO Masanori,TSUGE Masataka,MATSUO Taiji,TANAKA Shinji,HARUMA Ken,CHAYAMA Kazuaki
Journal of gastroenterology 44(11), 1118-1124, 2009-11-01
NAID 10027213278