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- 1. サラセミア症候群の分子病理 molecular pathology of the thalassemic syndromes
- 2. C型肝炎ウイルス感染に対する試験的治療 investigational therapies for hepatitis c virus infection
- 3. 成人における鉄欠乏性貧血の原因および診断 causes and diagnosis of iron deficiency anemia in the adult
English Journal
- Identification and functional characterization of an endoplasmic reticulum oxidoreductin 1-α gene in Litopenaeus vannamei.
- Zhang ZZ1, Yuan K1, Yue HT1, Yuan FH1, Bi HT1, Weng SP1, He JG2, Chen YH3.
- Developmental and comparative immunology.Dev Comp Immunol.2016 Apr;57:10-9. doi: 10.1016/j.dci.2015.11.013. Epub 2015 Nov 26.
- In the current study, full-length sequence of endoplasmic reticulum oxidoreductin 1-α (LvERO1-α) was cloned from Litopenaeus vannamei. Real-time RT-PCR results showed that LvERO1-α was highly expressed in hemocytes, gills, and intestines. White spot syndrome virus (WSSV) challenge was performed,
- PMID 26631649
- DBP-induced endoplasmic reticulum stress in male germ cells causes autophagy, which has a cytoprotective role against apoptosis in vitro and in vivo.
- Zhang G1, Liu K2, Ling X3, Wang Z4, Zou P5, Wang X6, Gao J7, Yin L8, Zhang X9, Liu J10, Ao L11, Cao J12.
- Toxicology letters.Toxicol Lett.2016 Mar 14;245:86-98. doi: 10.1016/j.toxlet.2016.01.016. Epub 2016 Jan 22.
- Recently, spermatogenic cell apoptosis was shown to play a key role in the induction of testicular atrophy by dibutyl phthalate (DBP), thus causing reproductive toxicology. However, the molecular events induced by DBP in apoptotic germ cells remain unclear. In the present study, the mouse spermatocy
- PMID 26804720
- PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage.
- Qu J1, Lu D2, Guo H1,3, Miao W1, Wu G1, Zhou M1.
- Clinical and experimental pharmacology & physiology.Clin Exp Pharmacol Physiol.2016 Mar;43(3):312-8. doi: 10.1111/1440-1681.12537.
- Glycolytic disorder has been demonstrated to be a major cause of osteoarthritis (OA) and chondrocyte dysfunction. The present work aimed to investigate the expression and role of the glycolytic regulator 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) in OA cartilage. It was found th
- PMID 26718307
Japanese Journal
- Methylglyoxal activates Gcn2 to phosphorylate eIF2α independently of the TOR pathway in Saccharomyces cerevisiae.
- Nomura Wataru,Maeta Kazuhiro,Kita Keiko,Izawa Shingo,Inoue Yoshiharu
- Applied microbiology and biotechnology 86(6), 1887-1894, 2010-05
- … Previously, we have reported that methylglyoxal attenuates the rate of overall protein synthesis in Saccharomyces cerevisiae through phosphorylation of the alpha subunit of translation initiation factor 2 (eIF2alpha) in a Gcn2-dependent manner. … Phosphorylation of eIF2alpha impedes the formation of a translation initiation complex, and subsequently, overall protein synthesis is reduced. …
- NAID 120002383972
- Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
- KOUMENIS C
- Mol Cell Biol 22, 7405-7416, 2002
- NAID 80015620484
- The amino acid sequence of the PKR-eIF2alpha phosphorylation homology domain of hepatitis C virus envelope 2 protein and response to interferon-alpha
- COCHRANE A
- J Infect Dis 182, 1515-1518, 2000
- NAID 30017493849
Related Links
- メーカー 商品コード 商品名 包装 価格 在庫 リスト GNT ジーンテックス GENETEX, Inc. GTX79090 Anti-eIF2alpha (phospho Ser51) 100μg \66,000 無 (未発注) 済 追加 データシート お問い合わせ 説明文 別名： phospho eIF2 alpha Ser51 ...
- Western blot analysis of extracts from PC12 cells, untreated or thapsigargin-treated (300 nM), using Phospho-eIF2alpha (Ser51) Antibody (upper) or eIF2alpha Antibody #9722 (lower). バックグラウンド Phosphorylation of the Int. J ...
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★リンクテーブル★
| リンク元 | 「真核生物翻訳開始因子2α」「eIF2α」 |
| 拡張検索 | 「eIF2alpha kinase」 |
「真核生物翻訳開始因子2α」
「eIF2α」
「eIF2alpha kinase」
- 関
- eIF-2alpha kinase