ダイニンATPアーゼ、ダイニン
- 関
- dynein
WordNet
- a unit of force equal to the force that imparts an acceleration of 1 cm/sec/sec to a mass of 1 gram
PrepTutorEJDIC
- ダイン(力の絶対単位;1グラムの物体に1秒につき1cm/秒の加速度を生じる力)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/08/26 10:48:53」(JST)
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Dynein ATPase |
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3.6.4.2 |
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Dynein ATPase (EC 3.6.4.2, dynein adenosine 5'-triphosphatase) is an enzyme with system name ATP phosphohydrolase (tubulin-translocating).[1][2][3] This enzyme catalyses the following chemical reaction
- ATP + H2O ADP + phosphate
This enzyme is a multisubunit protein complex associated with microtubules.
References
- ^ Summers, K.E. and Gibbons, I.R. (1971). "Adenosine triphosphate-induced sliding of tubules in trypsin-treated flagella of sea-urchin sperm". Proc. Natl. Acad. Sci. USA 68: 3092–3096. doi:10.1073/pnas.68.12.3092. PMID 5289252.
- ^ Gibbons, I.R. (1988). "Dynein ATPases as microtubule motors". J. Biol. Chem. 263: 15837–15840. PMID 2972702.
- ^ Gee, M. and Vallee, R. (1998). "The role of the dynein stalk in cytoplasmic and flagellar motility". Eur. Biophys. J. 27: 466–473. doi:10.1007/s002490050157. PMID 9760728.
See also
External links
- Dynein ATPase at the US National Library of Medicine Medical Subject Headings (MeSH)
UpToDate Contents
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English Journal
- Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains.
- Nicholas MP1, Berger F2, Rao L3, Brenner S3, Cho C4, Gennerich A5.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 May 4. pii: 201417422. [Epub ahead of print]
- Cytoplasmic dynein is a homodimeric microtubule (MT) motor protein responsible for most MT minus-end-directed motility. Dynein contains four AAA+ ATPases (AAA: ATPase associated with various cellular activities) per motor domain (AAA1-4). The main site of ATP hydrolysis, AAA1, is the only site consi
- PMID 25941405
- Dynein motors: How AAA+ ring opening and closing coordinates microtubule binding and linker movement.
- Schmidt H1.
- BioEssays : news and reviews in molecular, cellular and developmental biology.Bioessays.2015 May;37(5):532-43. doi: 10.1002/bies.201400215. Epub 2015 Mar 12.
- Dyneins are a family of motor proteins that move along the microtubule. Motility is generated in the motor domain, which consists of a ring of six AAA+ (ATPases associated with diverse cellular activities) domains, the linker and the microtubule-binding domain (MTBD). The cyclic ATP-hydrolysis in th
- PMID 25773057
- ATPases, ion exchangers and human sperm motility.
- Peralta-Arias RD1, Vívenes CY1, Camejo MI1, Piñero S1, Proverbio T1, Martínez E1, Marín R1, Proverbio F2.
- Reproduction (Cambridge, England).Reproduction.2015 May;149(5):475-84. doi: 10.1530/REP-14-0471.
- Human sperm has several mechanisms to control its ionic milieu, such as the Na,K-ATPase (NKA), the Ca-ATPase of the plasma membrane (PMCA), the Na(+)/Ca(2) (+)-exchanger (NCX) and the Na(+)/H(+)-exchanger (NHE). On the other hand, the dynein-ATPase is the intracellular motor for sperm motility. In t
- PMID 25820902
Japanese Journal
- クライオ電子線トモグラフィ法による真核生物鞭毛の立体構造解析
- 石川 尚
- 生物物理 52(4), 190-193, 2012-07-25
- … Flagella and cilia from various organisms share the common "9 + 2" structure in which nine microtubule doublets surround two singlet microtubules and are linked by dynein motor proteins. … However the mechanism to integrate the sliding motion of dynein into well-orchestrated bending was unknown. …
- NAID 10030494668
- 1M1636 微小管上のダイニン相互作用部位 : ATPase活性化、運動との関係性(分子モーター2,第49回日本生物物理学会年会)
- Uchimura Seiichi,Fujii Takashi,Takazaki Hiroko,Ayukawa Rie,Minoura Itsushi,Nishikawa Yosuke,Hachikubo You,Kon Takahide,Kurisu Genji,Sutoh Kazuo,Namba Keiichi,Muto Etsuko
- 生物物理 51(SUPPLEMENT_1), S65-S66, 2011-08-15
- NAID 110008903168
Related Links
- この中で唯一ダイニンのみが,AAA+ファミリーATPaseに属す. しかし,ダイニンは,形態の面でも機能の面でも他のAAA+ファミリーATPaseメンバーとは異なる特徴をいくつも持っている. ダイニン ...
- dynein /dy·ne·in/ (di´nēn) an ATP-splitting enzyme essential to the motility of cilia and flagella because of its interactions with microtubules. dy·nein (dī′nēn′, -nē-ĭn) n. An ATPase associated with motile structures, especially the ...
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- 英
- dynein ATPase
- 関
- ダイニン
[★]
- 同
- ATP hydrolase
- 関
- アデノシン三リン酸