デスモラーゼ
- 関
- lyase
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/01 21:13:10」(JST)
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A desmolase enzyme is one that catalyzes the formation or destruction of carbon-carbon bonds within a molecule. These enzymes play a significant role in respiration and fermentation.[1] Desmolases are involved in steroidogenesis.[citation needed]
Examples of desmolases are:
- Cholesterol side-chain cleavage enzyme, also called 20,22-desmolase; converts cholesterol to pregnenolone.
- 17,20 Desmolase, also called CYP17A1 or 17α-hydroxylase; converts pregnenolone to 17-hydroxypregnenolone, progesterone to 17-hydroxyprogesterone, and corticosterone to aldosterone.
- Diacetyl desmolase is added to beer late in the brewing process to remove diacetyl flavor that may have accumulated during processing.[2]
References
- ^ Wallerstein, Leo (1939). "Enzyme Preparations from Microorganisms: Commercial Production and Industrial Application". Industrial & Engineering Chemistry 31 (10): 1218–1224. doi:10.1021/ie50358a012.
- ^ Gutcho, Marcia Halpern (1969). Alcoholic Malt Beverages, 1969. Food Processing Reviews #7. Park Ridge, New Jersey: Noyes Development Corporation. p. 221. ISBN 978-0-8155-0282-1.
UpToDate Contents
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English Journal
- Comparative characterization of two marine alginate lyases from Zobellia galactanivorans reveals distinct modes of action and exquisite adaptation to their natural substrate.
- Thomas F, Lundqvist LC, Jam M, Jeudy A, Barbeyron T, Sandström C, Michel G, Czjzek M.SourceWoods Hole Oceanographic Institution, United States;
- The Journal of biological chemistry.J Biol Chem.2013 Jun 19. [Epub ahead of print]
- Cell walls of brown algae are complex supramolecular assemblies containing various original, sulfated and carboxylated polysaccharides. Among these, the major marine polysaccharide component, alginate, represents an important biomass that is successfully turned over by heterotrophic marine bacteria.
- PMID 23782694
- Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children.
- Ziegler AG, Rewers M, Simell O, Simell T, Lempainen J, Steck A, Winkler C, Ilonen J, Veijola R, Knip M, Bonifacio E, Eisenbarth GS.SourceInstitute of Diabetes Research, Helmholtz Zentrum München, and Forschergruppe Diabetes, Klinikum rechts der Isar, Technische Universität München, Ingolstaedter Landstrase 1, Neuherberg, Germany 85764. anette-g.ziegler@helmholtz-muenchen.de
- JAMA : the journal of the American Medical Association.JAMA.2013 Jun 19;309(23):2473-9. doi: 10.1001/jama.2013.6285.
- IMPORTANCE: Type 1 diabetes usually has a preclinical phase identified by circulating islet autoantibodies, but the rate of progression to diabetes after seroconversion to islet autoantibodies is uncertain.OBJECTIVE: To determine the rate of progression to diabetes after islet autoantibody seroconve
- PMID 23780460
- Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens.
- Ridlon JM, Ikegawa S, Alves JM, Zhou B, Kobayashi A, Iida T, Mitamura K, Tanabe G, Serrano M, De Guzman A, Cooper P, Buck GA, Hylemon PB.SourceVirginia Commonwealth University, United States;
- Journal of lipid research.J Lipid Res.2013 Jun 15. [Epub ahead of print]
- Clostridium scindens ATCC 35704 is capable of converting primary bile acids to toxic secondary bile acids, as well as converting glucocorticoids to androgens by side-chain cleavage. The molecular structure of the side-chain cleavage product of cortisol produced by C. scindens was determined to be 11
- PMID 23772041
Japanese Journal
- 精上皮腫を合併した男性仮性半陰陽の1例 : 17,20-desmolase欠損症 : 第139回関西地方会
- 善本 哲郎,辻本 幸夫,霞 弘之,松田 孝之,武田 守弘,平 省三,島 博基
- 日本泌尿器科學會雜誌 84(8), 1521-1522, 1993-08-20
- NAID 110003087556
- 男児先天性副腎皮質過形成(Desmolase欠損症)の1例 : 第62回宮崎地方会
- 岩川 愛一郎,妹尾 康平,上村 哲司,田苗 綾子,佐藤 克子
- 日本泌尿器科學會雜誌 83(9), 1541-1542, 1992-09-20
- NAID 110003068367
- Structures of regulatory regions in the human cytochrome P-450scc (desmolase) gene.
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- Medical Dictionary desmolase des·mo·lase (děz'mə-lās', -lāz') n. Any of various enzymes that break or form carbon-to-carbon bonds in a molecule and that play a role in respiration and fermentation. The American Heritage® Stedman ...
Related Pictures
★リンクテーブル★
[★]
- 英
- desmolase
- 関
- コレステロールデスモラーゼ
[★]
17,20-リアーゼ欠損症。デスモラーゼ欠損症