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English Journal
- Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression.
- Mallon S, Wakim BT, Roizman B.SourceThe Marjorie B. Kovler Viral Oncology Laboratories, University of Chicago, Chicago, IL 60637.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Dec 18;109(51):E3549-57. doi: 10.1073/pnas.1218783109. Epub 2012 Dec 5.
- Significance DNA introduced into cells by infection or transfection is immediately coated by repressive histones and repressors. Viruses have evolved mechanisms to derepress their genes. What we know of these events is based on ChIP analyses that help identify the proteins involved in these processe
- PMID 23223531
- Gonadotrophin-releasing hormone signalling downstream of calmodulin.
- Melamed P, Savulescu D, Lim S, Wijeweera A, Luo Z, Luo M, Pnueli L.SourceTechnion-Israel Institute of Technology, Haifa, Israel. phillippa.melamed@gmail.com
- Journal of neuroendocrinology.J Neuroendocrinol.2012 Dec;24(12):1463-75. doi: 10.1111/j.1365-2826.2012.02359.x.
- Gonadotrophin-releasing hormone (GnRH) regulates reproduction via binding a G-protein coupled receptor on the surface of the gonadotroph, through which it transmits signals, mostly via the mitogen-activated protein (MAPK) cascade, to increase synthesis of the gonadotrophin hormones: luteinising horm
- PMID 22775470
- IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.
- Upton JP, Wang L, Han D, Wang ES, Huskey NE, Lim L, Truitt M, McManus MT, Ruggero D, Goga A, Papa FR, Oakes SA.SourceDepartment of Pathology, University of California, San Francisco, San Francisco, CA 94143, USA.
- Science (New York, N.Y.).Science.2012 Nov 9;338(6108):818-22. doi: 10.1126/science.1226191. Epub 2012 Oct 4.
- The endoplasmic reticulum (ER) is the primary organelle for folding and maturation of secretory and transmembrane proteins. Inability to meet protein-folding demand leads to "ER stress," and activates IRE1α, an ER transmembrane kinase-endoribonuclease (RNase). IRE1α promotes adaptation through spl
- PMID 23042294
Japanese Journal
- Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice.
- Pandey Radha Raman,Tokuzawa Yoshimi,Yang Zhaolin,Hayashi Eri,Ichisaka Tomoko,Kajita Shimpei,Asano Yuka,Kunieda Tetsuo,Sachidanandam Ravi,Chuma Shinichiro,Yamanaka Shinya,Pillai Ramesh S
- Proceedings of the National Academy of Sciences of the United States of America 110(41), 16492-16497, 2013-10-08
- … Male mice carrying either a nonsense point mutation (reproductive mutant 23 or repro23 mice) or a targeted deletion in the Tdrd12 locus are infertile and derepress retrotransposons. …
- NAID 120005347109
- B cell–specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
- Honjo Tasuku,Nagaoka Hitoshi,Tran Thinh Huy,Nakata Mikiyo,Suzuki Keiichiro,Begum Nasim A,Shinkura Reiko,Fagarasan Sidonia
- Nature Immunology, 2009-12-06
- ゲノムに抗体の記憶を刻むAID蛋白質遺伝子（Aicda）の発現制御機構－何故非Bリンパ球にAIDが発現し、癌化が起こり得るのか－を解明しました. 京都大学プレスリリース. 2009-12-07. http://www.kyoto-u.ac.jp/ja/news_data/h/h1/news6/2009/091207_1.htmActivation-induced cyt …
- NAID 120001741673
- Identification and characterization of a second, inducible promoter of relA in Escherichia coli
- Nakagawa Akira,Oshima Taku,Mori Hirotada
- Genes & genetic systems 81(5), 299-310, 2006-10-25
- … Furthermore, the reduced activity of relAP2-lacZ in an hns mutant could be rescued by an rpoS mutation, which is sufficient to derepress the relAP2-lacZ activity. …
- NAID 10020145035
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