WordNet

destroy the myelin sheath of; "the disease demyelinated the nerve fibers"
loss of the myelin covering of some nerve fibers resulting in their impaired function

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1. 成人における多発性硬化症の診断 diagnosis of multiple sclerosis in adults
2. 浸透圧性脱髄症候群と低ナトリウム血症の過度に急速な補正 osmotic demyelination syndrome and overly rapid correction of hyponatremia
3. 小児における中枢神経系の急性脱髄の鑑別診断 differential diagnosis of acute central nervous system demyelination in children
4. 慢性炎症性脱髄性多発神経炎：病因、臨床的特徴、および診断 chronic inflammatory demyelinating polyneuropathy etiology clinical features and diagnosis
5. 神経伝導検査の概要 overview of nerve conduction studies

Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia.

Hendrickx DA, Schuurman KG, van Draanen M, Hamann J, Huitinga I1.
Journal of neuroinflammation.J Neuroinflammation.2014 Mar 31;11:64. doi: 10.1186/1742-2094-11-64.
BACKGROUND: The pathological hallmark of multiple sclerosis (MS) is myelin phagocytosis. It remains unclear why microglia and macrophages demyelinate axons in MS, but previously found or yet-unknown changes in the myelin of MS patients could contribute to this process. We therefore studied whether m
PMID 24684721

Theiler's murine encephalomyelitis virus L* amino acid position 93 is important for virus persistence and virus-induced demyelination.

Stavrou S1, Baida G, Viktorova E, Ghadge G, Agol VI, Roos RP.
Journal of virology.J Virol.2010 Feb;84(3):1348-54. doi: 10.1128/JVI.01585-09. Epub 2009 Nov 18.
The DA strain and other members of the TO subgroup of Theiler's murine encephalomyelitis virus (TMEV) induce a persistent central nervous system infection associated with an inflammatory white matter demyelinating disease. TO subgroup strains synthesize an 18-kDa protein, L*, out of frame with the p
PMID 19923182

Brainstem 1H nuclear magnetic resonance (NMR) spectroscopy: marker of demyelination and repair in spinal cord.

Denic A1, Bieber A, Warrington A, Mishra PK, Macura S, Rodriguez M.
Annals of neurology.Ann Neurol.2009 Oct;66(4):559-64. doi: 10.1002/ana.21758.
Measuring in vivo spinal cord injury and repair remains elusive. Using magnetic resonance spectroscopy (MRS) we examined brainstem N-acetyl-aspartate (NAA) as a surrogate for spinal cord injury in two mouse strains with different reparative phenotypes following virus-induced demyelination. Swiss Jim
PMID 19816926

皆内康広
日本らい学会雑誌 57(3), 137-148, 1988
… leprae mainly enter the nerve trunks through distally running dermal nerves and primarily demyelinate sensory fibers centripetally during patients' lives. …
NAID 130003920731