D細胞。δ細胞
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- an object shaped like an equilateral triangle
- a low triangular area of alluvial deposits where a river divides before entering a larger body of water; "the Mississippi River delta"; "the Nile delta"
- the 4th letter of the Greek alphabet
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- デルタ(ギリシア語アルファベットの第4字Δ,δ;英語D,dに相当) / (河口の)三角州,デルタ / 三角形をしたもの
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/02/25 23:59:30」(JST)
[Wiki en表示]
Not to be confused with D battery.
Delta cell |
Control of stomach acid
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Details |
Identifiers |
Latin |
endocrinocytus D |
MeSH |
D+Cells |
Code |
TH H3.04.02.0.00027 |
Anatomical terminology
[edit on Wikidata]
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Delta cells (δ-cells or D cells) are somatostatin-producing cells. They can be found in the stomach, intestine and the pancreatic islets. In rodents, delta-cells are located in the periphery of the islets; in humans the islet architecture is generally less organized and delta-cells are frequently observed inside the islets as well. Viewed under an electron microscope, delta-cells can be identified as cells with smaller and slightly more compact granules than beta cells. D cells contain CCKBR (which respond to gastrin) and M3 receptors (which respond to Ach). Respectively, these receptors will increase somatostatin output and decrease somatostatin output from the D cells. VIP, vasoactive intestinal peptide, acts positively on D cells resulting in more somatostatin being released.
Clinical significance
A tumor of the delta cells is called a "somatostatinoma".
When a person is infected with H. pylori the lower region of the stomach, the antrum, is predominantly inflamed. This is where most of the D cells in the stomach are. The bacteria produce a cloud of ammonia around themselves using urease to protect them from the stomach acid; however, this reacts with the acid producing ammonium which is toxic to cells. This leads to many of the D cells dying and therefore a lower level of somatostatin being secreted. This results in higher levels of gastrin and stomach acid being secreted. This, combined with the damage from ammonium, leads to ulceration of the stomach wall.[1]
References
- ^ Liu, Y. (2005). Gastrin (G) cells and somatostatin (D) cells in patients with dyspeptic symptoms: Helicobacter pylori associated and non-associated gastritis. Journal of Clinical Pathology, 58(9), pp.927-931.
Physiology of the gastrointestinal system
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GI tract |
Upper |
Exocrine |
- Chief cells
- Parietal cells
- Gastric acid
- Intrinsic factor
- Foveolar cells
- Goblet cells
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Processes |
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Fluids |
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Lower |
Enteric nervous system |
- Submucous plexus
- Myenteric plexus
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Endocrine/paracrine |
- G cells
- D cells
- ECL cells
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enterogastrone: |
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- Enteroendocrine cells
- Enterochromaffin cell
- APUD cell
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Fluids |
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Processes |
- Segmentation contractions
- Migrating motor complex
- Borborygmus
- Defecation
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Either/both |
Processes |
- Peristalsis (Interstitial cell of Cajal
- Basal electrical rhythm)
- Gastrocolic reflex
- Digestion
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Accessory |
Fluids |
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Processes |
- Enterohepatic circulation
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Abdominopelvic |
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Cells in humans derived from endoderm
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Foregut |
Respiratory |
- Pneumocyte
- Club cell
- Goblet cell
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Digestive |
Stomach |
- Enteroendocrine cell
- G cell
- Delta cell
- Enterochromaffin-like cell
- Gastric chief cell
- Parietal cell
- Foveolar cell
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Intestine |
- Enteroendocrine cell
- Gastric inhibitory polypeptide
- S cell
- Delta cell
- Cholecystokinin
- Goblet cell
- Paneth cell
- Enterocyte
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Liver |
- Hepatocyte
- Hepatic stellate cell
- (Kupffer cell from mesoderm)
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Gallbladder |
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Exocrine pancreas |
- Centroacinar cell
- Pancreatic stellate cell
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Islets of Langerhans |
- alpha cell
- beta cell
- delta cell
- F cell(PP cell
- epsilon cell
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Pharyngeal pouch |
- Thyroid gland
- Parathyroid gland
- Parathyroid chief cell
- Oxyphil cell
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Hindgut/cloaca |
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UpToDate Contents
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English Journal
- Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors.
- Xin M1, Duan W1, Feng Y1, Hei YY1, Zhang H1, Shen Y1, Zhao HY1, Mao S1, Zhang SQ1.
- Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2018 Dec;33(1):651-656. doi: 10.1080/14756366.2018.1444608.
- PMID 29536777
- Proteomic analyses for profiling regulated proteins/enzymes by Fucus vesiculosus fucoidan in B16 melanoma cells: A combination of enzyme kinetics functional study.
- Wang ZJ1, Zheng L2, Yang JM3, Kang Y4, Park YD5.
- International journal of biological macromolecules.Int J Biol Macromol.2018 Jun;112:667-674. doi: 10.1016/j.ijbiomac.2018.02.011. Epub 2018 Feb 3.
- PMID 29408614
- Production and characterization of a novel Delta-like 1 functional unit as a tool for Notch pathway activation and generation of a specific antibody.
- Ferreira A1, Lamy M2, Margarida Rocha M1, Silva G1, Bandeiras TM3, Barbas A4.
- Protein expression and purification.Protein Expr Purif.2018 Jun;146:8-16. doi: 10.1016/j.pep.2018.01.008. Epub 2018 Jan 31.
- PMID 29366964
Japanese Journal
- Asymptomatic Reactive Hypoglycemia and Inflammatory Reaction in Patients with Coronary Artery Disease
- Sex-Specific Association of Serum 25-Hydroxyvitamin D<sub>3</sub> with Insulin Resistance in Chinese Han Patients with Newly Diagnosed Type 2 Diabetes Mellitus
- Journal of Nutritional Science and Vitaminology 64(3), 173-178, 2018-06-30
- NAID 130007413206
- Chemical compatibility of Sr<sub>2</sub>MgMoO<sub>6−δ</sub> with representative electrolyte materials and interlayer materials for solid oxide fuel cells
Related Links
- Delta cells (δ-cells or D cells) are somatostatin-producing cells. ... In rodents delta -cells are located in the periphery of the islets; in humans the islet architecture is generally less ... A tumor of the delta cells is called a "somatostatinoma".
★リンクテーブル★
[★]
- 関
- D cell、delta cell、pancreatic delta cell、somatostatin-secreting cell
[★]
- 関
- D cell、delta cell、pancreatic delta cell、somatostatin cell
[★]
膵δ細胞
- 関
- D cell、delta cell、somatostatin cell、somatostatin-secreting cell
[★]
δ、デルタ
[★]
細胞