decompensation

• n.

• 補償作用の喪失
• (医)(心臓の)代償不全

　

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1. (心臓の)代償不全

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/06/02 04:33:59」(JST)

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In medicine, decompensation is the functional deterioration of a previously working structure or system. Decompensation may occur due to fatigue, stress, illness, or old age. When a system is "compensated", it is able to function despite stressors or defects. Decompensation describes an inability to compensate for these deficiencies. It is a general term commonly used in medicine to describe a variety of situations.

Physiology

For example, cardiac decompensation may refer to the failure of the heart to maintain adequate blood circulation, after long-standing (previously compensated) vascular disease (see heart failure). Short-term treatment of cardiac decompensation can be achieved through administration of dobutamine, resulting in an increase in heart contractility via an inotropic effect.

Kidney failure can also occur following a slow degradation of kidney function due to an underlying untreated illness, the symptoms of the latter can then become much more severe due to the lack of efficient compensation by the kidney.

Psychology

In psychology, the term refers to the inability to maintain defense mechanisms in response to stress, resulting in personality disturbance or psychological imbalance.

References

• Joseph et al. (2009). "Acute Decompensated Heart Failure". Texas Heart Institute Journal. Retrieved 18 October 2012.  CS1 maint: Explicit use of et al. (link)

UpToDate Contents

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• 1. 心原性肺水腫の病態生理 pathophysiology of cardiogenic pulmonary edema
• 2. 急性非代償性心不全の治療：一般的な考慮事項 treatment of acute decompensated heart failure general considerations
• 3. 緩和ケアにおける疲労、脱力および無力症の概要 overview of fatigue weakness and asthenia in palliative care
• 4. 原発性胆汁性肝硬変における肝移植 liver transplantation in primary biliary cirrhosis
• 5. 先天性代謝異常：個々の障害の発見 inborn errors of metabolism identifying the specific disorder

English Journal

• Carnitine-acylcarnitine translocase deficiency: Two neonatal cases with common splicing mutation and in vitro bezafibrate response.

• Vatanavicharn N1, Yamada K2, Aoyama Y3, Fukao T4, Densupsoontorn N5, Jirapinyo P5, Sathienkijkanchai A6, Yamaguchi S2, Wasant P6.
• Brain & development.Brain Dev.2015 Aug;37(7):698-703. doi: 10.1016/j.braindev.2014.10.005. Epub 2014 Nov 1.
• BACKGROUND: Mitochondrial fatty acid oxidation (FAO) disorders are among the causes of acute encephalopathy- or myopathy-like illness. Carnitine-acylcarnitine translocase (CACT) deficiency is a rare FAO disorder, which represent an energy production insufficiency during prolonged fasting, febrile il
• PMID 25459972

• Prognostic significance of quantitative assessment of focal myocardial fibrosis in patients with heart failure with preserved ejection fraction.

• Kato S1, Saito N2, Kirigaya H2, Gyotoku D2, Iinuma N2, Kusakawa Y2, Iguchi K2, Nakachi T2, Fukui K2, Futaki M3, Iwasawa T3, Taguri M4, Kimura K5, Umemura S6.
• International journal of cardiology.Int J Cardiol.2015 Jul 15;191:314-9. doi: 10.1016/j.ijcard.2015.05.048. Epub 2015 May 9.
• BACKGROUND: The aim of this study was to investigate the prognostic value of myocardial focal fibrosis quantified by late gadolinium enhanced (LGE) magnetic resonance imaging (MRI) in patients with heart failure with preserved ejection fraction (HFpEF).METHODS: One-hundred eleven HFpEF patients (mea
• PMID 26005800

• Energy loss in the left ventricle obtained by vector flow mapping as a new quantitative measure of severity of aortic regurgitation: a combined experimental and clinical study.

• Stugaard M1, Koriyama H1, Katsuki K2, Masuda K1, Asanuma T1, Takeda Y2, Sakata Y2, Itatani K3, Nakatani S4.
• European heart journal cardiovascular Imaging.Eur Heart J Cardiovasc Imaging.2015 Jul;16(7):723-30. doi: 10.1093/ehjci/jev035. Epub 2015 Mar 9.
• AIMS: In aortic regurgitation (AR), energy loss (EL) produced by inefficient turbulent flow may be a burden to the heart predicting decompensation. We attempted to quantify EL in AR induced in an acute dog model and in patients with chronic AR using novel echocardiographic method vector flow mapping
• PMID 25762562

Japanese Journal

• 下顎前突症患者における術前矯正治療後の前歯歯軸傾斜

• 大久保 和美,須佐美 隆史,井口 隆人,岡安 麻里,髙橋 直子,上床 喜和子,内野 夏子,末永 英之,古賀 陽子,西條 英人,森 良之,髙戸 毅
• 日本顎変形症学会雑誌 24(1), 16-26, 2014
• … 骨格性下顎前突症患者における術前矯正治療による前歯歯軸のdecompensationの実態を把握すること，および術前矯正治療の有効性についてのエビデンスを得ることを目的とし，顎矯正手術直前の上下顎前歯歯軸と術前矯正治療中の歯軸変化について検討を行った。 …
• NAID 130003397166

• 中村賞受賞者 水疱性角膜症の瘢痕形成の検出と臨床的意義

• 森重 直行
• 山口医学 = Yamaguchi medical journal 62(2), 85-90, 2013-05
• … 角膜症の罹病期間が角膜実質の瘢痕性変化に影響することが明らかとなり,さらには水疱性角膜症の罹病期間が角膜内皮移植後の視力予後に影響することを見いだした.これらのことから,水疱性角膜症は病理組織学的にも臨床的にも罹病期間依存性進行性疾患であるということを提唱するに至った.The pathogenesis of bullous keratopathy is corneal endothelial decompensation, resulting that the clinical appearance of bullous keratopathy is corneal stromal …
• NAID 120005246410

• Eosinophilic Myocarditis due to Churg-Strauss Syndrome With Markedly Elevated Eosinophil Cationic Protein

• Hara Tomoya,Yamaguchi Koji,Iwase Takashi,Kadota Muneyuki,Bando Mika,Ogasawara Kozue,Bando Sachiko,Ise Takayuki,Niki Toshiyuki,Ueda Yuka,Tomita Noriko,Taketani Yoshio,Yamada Hirotsugu,Soeki Takeshi,Wakatsuki Tetsuzo,Sata Masataka
• International Heart Journal 54(1), 51-53, 2013
• … Chest X-rays showed cardiac decompensation and an electrocardiogram revealed a new ST-T change. …
• NAID 130003364440

Related Links

• Decompensation - Wikipedia, the free encyclopedia

In medicine, decompensation is the functional deterioration of a previously working structure or system. Decompensation may occur due to fatigue, stress, illness, or old age. When a system is "compensated", it is able to function despite ...

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★リンクテーブル★

リンク元	「代償不全」
拡張検索	「heart decompensation」

「代償不全」

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英

decompensation

関

僧帽弁閉鎖不全症

「heart decompensation」

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• 心代償不全

関

cardiac failure、congestive heart failure、heart failure