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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/17 12:37:06」(JST)

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Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein.

Hou YS1, Liu LY1, Chai JK1, Yu YH1, Duan HJ1, Hu Q1, Yin HN1, Wang YH1, Zhuang SB1, Fan J1, Chu WL1, Ma L1.
Molecular medicine reports.Mol Med Rep.2015 Aug;12(2):2521-8. doi: 10.3892/mmr.2015.3723. Epub 2015 May 4.
Mesenchymal stem cell (MSC)-based regenerative therapy is currently regarded as a novel approach with which to repair damaged tissues. However, the efficiency of MSC transplantation is limited due to the low survival rate of engrafted MSCs. Lipopolysaccharide (LPS) production is increased in numerou
PMID 25955291

Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway.

Qian Y1, Cao L, Guan T, Chen L, Xin H, Li Y, Zheng R, Yu D.
Pharmaceutical biology.Pharm Biol.2015 Aug;53(8):1124-32. doi: 10.3109/13880209.2014.962057. Epub 2015 Feb 26.
CONTEXT: Genistein, one of the isoflavones derived from soybean seeds, has been reported to exert multiple bioactivities. However, the mechanism of its action on the central nervous system is not fully understood.OBJECTIVE: To investigate the cytoprotection of genistein and its molecular mechanism a
PMID 25715966

Brain mitochondrial ATP-insensitive large conductance Ca(+2)-activated K(+) channel properties are altered in a rat model of amyloid-β neurotoxicity.

Jafari A1, Noursadeghi E2, Khodagholi F2, Saghiri R3, Sauve R4, Aliaghaei A5, Eliassi A6.
Experimental neurology.Exp Neurol.2015 Jul;269:8-16. doi: 10.1016/j.expneurol.2014.12.024. Epub 2015 Mar 28.
Mitochondrial dysfunction is a hallmark of amyloid-beta (Aβ)-induced neuronal toxicity in Alzheimer's disease (AD). However, the underlying mechanism of how Aβ affects mitochondrial function remains uncertain. Because mitochondrial potassium channels have been involved in several mitochondrial fun
PMID 25828534

Proceedings of the Japan Academy, Series B 91(4), 131-159, 2015
… After the identification of endogenous H2S in the mammalian brain two decades ago, studies of this molecule uncovered physiological roles in processes such as neuromodulation, vascular tone regulation, cytoprotection against oxidative stress, angiogenesis, anti-inflammation, and oxygen sensing. …
NAID 130005061418

Nrf2-mediated mucoprotective and anti-inflammatory actions of Artemisia extracts led to attenuate stress related mucosal damages

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Journal of Clinical Biochemistry and Nutrition 56(2), 132-142, 2015
… Antioxidant activities were evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) method and confocal microscopy on lipopolysaccharide-induced RGM1 cells, cytoprotection effects evaluated by detecting heme oxygenase-1 (HO-1), Nf-E2 related factor2 (Nrf2) and heat shock protein 70 (HSP70), and anti-inflammatory effects investigated by measuring inflammatory mediators. …
NAID 130004879379

Nitric Oxide Is an Important Regulator of Heme Oxygenase-1 Expression in the Lipopolysaccharide and Interferon-γ-Treated Murine Macrophage-Like Cell Line J774.1/JA-4

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Biological and Pharmaceutical Bulletin 38(1), 7-16, 2015
… The HO-1 products provide antioxidant cytoprotection in addition to having potent antiinflammatory and immunomodulatory functions. …
NAID 130004872231