WordNet

of a compound having atoms arranged in a ring structure
recurring in cycles (同)cyclical
conforming to the Carnot cycle
forming a whorl or having parts arranged in a whorl; "cyclic petals"; "cyclic flowers"
marked by repeated cycles
a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs" (同)antibiotic drug
of or relating to antibiotic drugs

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1. 腸球菌における抗菌薬耐性の機構 mechanisms of antibiotic resistance in enterococci
2. βラクタム系抗生物質の長期注入投与 prolonged infusions of beta lactam antibiotics
3. 小児におけるメチシリン耐性黄色ブドウ球菌感染：侵襲性感染症の治療 methicillin resistant staphylococcus aureus in children treatment of invasive infections
4. 抗菌薬感受性試験の概要 overview of antibacterial susceptibility testing
5. 腸球菌感染症の治療 treatment of enterococcal infections

Cellular uptake and localization of polymyxins in renal tubular cells using rationally designed fluorescent probes.

Yun B1, Azad MA2, Nowell CJ3, Nation RL2, Thompson PE4, Roberts KD1, Velkov T5, Li J5.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Sep 21. pii: AAC.01216-15. [Epub ahead of print]
Polymyxins are cyclic lipopeptide antibiotics that serve as a last-line defence against Gram-negative 'superbugs'. However, the extensive accumulation of polymyxins in renal tubular cells can lead to nephrotoxicity which is the major dose-limiting factor in clinical use. In order to gain further ins
PMID 26392495

Real-World Treatment of Enterococcal Infections with Daptomycin: Insights from a Large European Registry (EU-CORE).

Lübbert C1, Rodloff AC2, Hamed K3.
Infectious diseases and therapy.Infect Dis Ther.2015 Sep;4(3):259-71. doi: 10.1007/s40121-015-0072-z. Epub 2015 Jul 14.
INTRODUCTION: Evolution of antibacterial resistance in pathogenic enterococcal strains poses a growing therapeutic challenge. Daptomycin, a cyclic lipopeptide, exhibits broad antibiotic activity against Gram-positive bacteria.METHODS: The European Cubicin(®) Outcomes Registry and Experience, a mult
PMID 26168986

Mutations associated with reduced surotomycin susceptibility in Clostridium difficile and Enterococcus species.

Adams HM1, Li X1, Mascio C2, Chesnel L2, Palmer KL3.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jul;59(7):4139-47. doi: 10.1128/AAC.00526-15. Epub 2015 May 4.
Clostridium difficile infection (CDI) is an urgent public health concern causing considerable clinical and economic burdens. CDI can be treated with antibiotics, but recurrence of the disease following successful treatment of the initial episode often occurs. Surotomycin is a rapidly bactericidal cy
PMID 25941217

Inhibition of Lipopolysaccharide Activity by a Bacterial Cyclic Lipopeptide Surfactin

Structure Determination of Glycinocins A to D, Further Evidence for the Cyclic Structure of the Amphomycin Antibiotics

Friulimicins. Novel Lipopeptide Antibiotics with Peptidoglycan Synthesis Inhibiting Activity from Actinoplanes friuliensis sp. nov. II. Isolation and Structural Characterization.:II. Isolation and Structural Characterization