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English Journal

Middle cerebral artery territory infarct due to Cryptococcus infectionstitle: An uncommon indication for cerebrospinal fluid analysis in stroke patients.

Cachia D1, Singh C2, Tetzlaff MT3, Penas-Prado M1.
Diagnostic cytopathology.Diagn Cytopathol.2015 Aug;43(8):632-4. doi: 10.1002/dc.23219. Epub 2014 Oct 28.
Cryptococcal meningitis is the most common manifestation of cryptococcosis and is caused by the encapsulated yeast organism Cryptococcus neoformans. It occurs most commonly in patients with impaired cell-mediated immunity such as in HIV infection; patients with hematological malignancies; patients p
PMID 25352313

Neurogenic pulmonary edema following Cryptococcal meningoencephalitis associated with HIV infection.

Kondo R1,2,3, Sugita Y1, Arakawa K4, Nakashima S1, Umeno Y1, Todoroki K1, Yoshida T3, Takase Y3, Kage M2,3, Oshima K1, Yano H1.
Neuropathology : official journal of the Japanese Society of Neuropathology.Neuropathology.2015 Aug;35(4):343-7. doi: 10.1111/neup.12193. Epub 2015 May 7.
Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema following a significant central nervous system insult. Only a few cases of NPE after Cryptococcal meningitis have been reported. We report a case of NPE following Cryptococcal meningoencephali
PMID 25955768

Fungal Inositol Pyrophosphate IP7 Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity.

Lev S1, Li C1, Desmarini D1, Saiardi A2, Fewings NL3, Schibeci SD3, Sharma R4, Sorrell TC, Djordjevic JT5.
mBio.MBio.2015 Jun 2;6(3):e00531-15. doi: 10.1128/mBio.00531-15.
Inositol pyrophosphates (PP-IPs) comprising inositol, phosphate, and pyrophosphate (PP) are essential for multiple functions in eukaryotes. Their role in fungal pathogens has never been addressed. Cryptococcus neoformans is a model pathogenic fungus causing life-threatening meningoencephalitis. We i
PMID 26037119

An Autopsy Case of Disseminated Cryptococcosis Manifesting as Acute Diarrhea in a Patient with Primary Biliary Cirrhosis

Hokari Satoshi,Tsukada Hiroki,Ito Kazuhisa,Shibuya Hiroyuki
Internal Medicine 49(16), 1793-1796, 2010
… An autopsy showed intracapillary cryptococci in the systemic organs, especially in the intestinal tract. …
NAID 130000299645

岸一馬,本間栄,黒崎敦子,中村茂樹,吉村邦彦
感染症学雑誌 78(4), 327-330, 2004
… According to these findings, a diagnosis of primary pulmonary cryptococcosis was made, although cryptococci were neither recognized in the specimen nor cultured from the bronchial lavaged fluid. …
NAID 130004331183

Histopathology of Deep-Seated Fungal Infections and Detailed Examination of Granulomatous Response Against Cryptococci in Patients with Acquired Immunodeficiency Syndrome