WordNet

magnifier of the image of small objects; "the invention of the microscope led to the discovery of the cell"

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Development of a novel cryogenic microscope with numerical aperture of 0.9 and its application to photosynthesis research.

Shibata Y1, Katoh W2, Chiba T3, Namie K3, Ohnishi N4, Minagawa J4, Nakanishi H2, Noguchi T2, Fukumura H3.
Biochimica et biophysica acta.Biochim Biophys Acta.2014 Jun;1837(6):880-7. doi: 10.1016/j.bbabio.2014.03.006. Epub 2014 Mar 17.
A novel cryogenic optical-microscope system was developed in which the objective lens is set inside of the cryostat adiabatic vacuum space. Being isolated from the sample when it was cooled, the objective lens was maintained at room temperature during the cryogenic measurement. Therefore, the author
PMID 24650629

Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity.

Oda T1, Yanagisawa H, Yagi T, Kikkawa M.
The Journal of cell biology.J Cell Biol.2014 Mar 3;204(5):807-19. doi: 10.1083/jcb.201312014.
Cilia/flagella are conserved organelles that generate fluid flow in eukaryotes. The bending motion of flagella requires concerted activity of dynein motors. Although it has been reported that the central pair apparatus (CP) and radial spokes (RSs) are important for flagellar motility, the molecular
PMID 24590175

Palmer CM1, Löwe J2.
Ultramicroscopy.Ultramicroscopy.2014 Feb;137:20-9. doi: 10.1016/j.ultramic.2013.10.016. Epub 2013 Nov 13.
The use of slab-like flat specimens for electron cryo-tomography restricts the range of viewing angles that can be used. This leads to the "missing wedge" problem, which causes artefacts and anisotropic resolution in reconstructed tomograms. Cylindrical specimens provide a way to eliminate the probl
PMID 24275523